Bromfenac Sodium
![Bromfenac Sodium Structure](CAS/GIF/120638-55-3.gif)
- CAS No.
- 120638-55-3
- Chemical Name:
- Bromfenac Sodium
- Synonyms
- Duract;Unii-8ecv571Y37;Bromfenac sodiu;Bromfenac sodium;Bromfenac ophthalmic;acetate hydrate(2:2:3);Bromfenac sodium hydrate;BroMfenac sodiuM 1.5H2O;Sodium bromfenate hydrate;Bromfenac ophthalmic solution
- CBNumber:
- CB82130312
- Molecular Formula:
- C15H11BrNNaO3
- Molecular Weight:
- 356.15
- MOL File:
- 120638-55-3.mol
- Modify Date:
- 2024/7/2 8:55:18
SAFETY
Risk and Safety Statements
Signal word | Danger |
---|---|
Hazard statements | H372-H300 |
Precautionary statements | P260-P264-P270-P314-P501-P264-P270-P301+P310-P321-P330-P405-P501 |
Bromfenac Sodium Chemical Properties,Uses,Production
Description
Duract was launched in the US as a potent, orally-active, long lasting peripheral analgesic with antiinflammatory properties. It is structurally similar to ketoprofen and diclofenac and can be prepared in three steps from 2-amino-4’-bromophenone using Gassman’s oxindole synthesis. Duract’s biological effects are a result of its ability to reduce prostaglandin production through inhibition of cyclooxygenase. As a 4-bromo derivative of Amfenac, this modification increased the duration of analgesic activity and antiinflammatory potency. It was also free of any CNS, cardiovascular or autonomic effects. In comparison, 5 mg of Duract was equipotent to 650 mg of ASA and 25 mg was slightly more potent than 400 mg of Ibuprofen.
Chemical Properties
Yellow Solid
Uses
Bromfenac is a non-steroidal anti-inflammatory agent.
Definition
ChEBI: The sesquihydrate of the sodium salt of bromfenac. It is used for the management of ocular pain and treatment of postoperative inflammation in patients who have undergone cataract extraction.
Bromfenac Sodium Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Anant Pharmaceuticals Pvt Ltd | +91-8550986868 +91-9485998001 | Haryana, India | 461 | 58 | Inquiry |
Flax Laboratories | +91-9867665132 +91-9867665132 | Maharashtra, India | 44 | 58 | Inquiry |
Vadivarhe Speciality Chemicals Limited | +91-9028832204 +91-9028832204 | Maharashtra, India | 38 | 58 | Inquiry |
Medilux Laboratories Pvt Ltd | +91-7292409991 +91-9819666688 | Madhya Pradesh, India | 102 | 58 | Inquiry |
Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
Vaqure Remedies | 08047313566 | Haryana, India | 2 | 58 | Inquiry |
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