21-Hydroxy Eplerenone

21-Hydroxy Eplerenone Structure
CAS No.
334678-67-0
Chemical Name:
21-Hydroxy Eplerenone
Synonyms
21-Hydroxy Eplerenone;21-Hydroxyeplerenone (α, β mixture);9,11α-epoxy-17α,21-dihydroxy-3-oxo-pregn-4-ene-7α,21-dicarboxylic acid, γ-lactone, methyl ester;Pregn-4-ene-7,21-dicarboxylic acid, 9,11-epoxy-17,21-dihydroxy-3-oxo-, γ-lactone, methyl ester, (7α,11α,17α)-
CBNumber:
CB82706405
Molecular Formula:
C24H30O7
Molecular Weight:
430.5
MOL File:
334678-67-0.mol
Modify Date:
2023/5/18 11:31:16

21-Hydroxy Eplerenone Properties

Melting point >223°C (dec.)
Boiling point 617.8±55.0 °C(Predicted)
Density 1.37±0.1 g/cm3(Predicted)
storage temp. Refrigerator, under inert atmosphere
solubility Chloroform (Slightly), Methanol (Slightly)
pka 12.90±0.70(Predicted)
form Solid
color White

21-Hydroxy Eplerenone Chemical Properties,Uses,Production

Uses

21-Hydroxyeplerenone is a metabolite of Eplerenone (E588775), which is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure. 21-Hydroxyeplerenone is a metabolite of eplerenone in humans and dogs.

21-Hydroxy Eplerenone Preparation Products And Raw materials

Raw materials

Preparation Products

21-Hydroxy Eplerenone 21-Hydroxyeplerenone (α, β mixture) Pregn-4-ene-7,21-dicarboxylic acid, 9,11-epoxy-17,21-dihydroxy-3-oxo-, γ-lactone, methyl ester, (7α,11α,17α)- 9,11α-epoxy-17α,21-dihydroxy-3-oxo-pregn-4-ene-7α,21-dicarboxylic acid, γ-lactone, methyl ester 334678-67-0