DifluoroiodoMethyl phenyl sulfone
- CAS No.
- 802919-90-0
- Chemical Name:
- DifluoroiodoMethyl phenyl sulfone
- Synonyms
- DifluoroiodoMethyl phenyl sulfone;(difluoroiodomethylsulfonyl)benzene;Benzene, [(difluoroiodomethyl)sulfonyl]-
- CBNumber:
- CB82709840
- Molecular Formula:
- C7H5F2IO2S
- Molecular Weight:
- 318.08
- MOL File:
- 802919-90-0.mol
- Modify Date:
- 2024/1/22 13:00:37
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Safety Statements | 24/25 |
| HS Code | 29309090 |
DifluoroiodoMethyl phenyl sulfone Chemical Properties,Uses,Production
Description
A visible light-catalysed direct and regioselective (phenylsulfonyl) difluoromethylation of imidazo[1,2-A]pyridines and benzo[d]-imidazo[2,1-b]thiazoles was carried out by DifluoroiodoMethyl phenyl sulfone under mild conditions. This synthetic methodology enables the introduction of a CF2SO2Ph group in an efficient and regioselective reaction through C-H bond functionalization with a broad substrate scope in good to excellent yields.
Uses
Iododifluoromethyl phenyl sulfone can be used for the difluoromethylation of alkenes and alkynes initiated by triethylborane/air or arenediazonium salt/titanium chloride in moderate to good yields.
Reactions
(1) Difluoromethylation of terminal alkenes and alkynes.
References
[1] GUO-JIE YIN; W. F; Mei Zhu. Visible-light mediated regioselective (phenylsulfonyl)difluoromethylation of fused imidazoles with iododifluoromethyl phenyl sulfone[J]. Heterocyclic Communications, 2017. DOI:10.1515/hc-2017-0101.
[2] YA LI. Radical (Phenylsulfonyl)difluoromethylation with Iododifluoromethyl Phenyl Sulfone[J]. The Journal of Organic Chemistry, 2007. DOI:10.1021/jo070618s.
DifluoroiodoMethyl phenyl sulfone Preparation Products And Raw materials
Raw materials
Preparation Products
DifluoroiodoMethyl phenyl sulfone Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
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| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
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| Shanghai Lingfu Pharmaceutical Research Co. LTD | 400-8675577 19945755304 | China | 9939 | 58 | Inquiry |
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