ChemicalBook > Product Catalog >Organic Chemistry >Carboxylic acids and derivatives >Carboxylic acid esters and derivatives >Trifluoromethanesulfonic acid difluoromethyl ester

Trifluoromethanesulfonic acid difluoromethyl ester

CAS No.: 1885-46-7

Chemical Name:: Trifluoromethanesulfonic acid difluoromethyl ester

Synonyms: Difluoromethyl triflate;Difluoromethyl triflate 95%;Difluoromethyl trifluoromethanesulfonate;Difluoromethyl trifluoromethanesulfonate 95%;Trifluoromethanesulfonic acid difluoromethyl ester;Methanesulfonic acid, 1,1,1-trifluoro-, difluoromethyl ester

CBNumber:: CB82755645

Molecular Formula:: C2HF5O3S

Molecular Weight:: 200.08

MOL File:: 1885-46-7.mol

MSDS File:: SDS

Modify Date:: 2024/4/15 18:41:30

Request For Quotation

Trifluoromethanesulfonic acid difluoromethyl ester Properties

Boiling point	48.5-49 °C
Density	1.584 g/mL at 25 °C
Flash point	57℃
storage temp.	2-8°C
form	liquid
color	Clear, colourless

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS02,GHS05,GHS07
Signal word	Danger
Hazard statements	H226-H302-H314
Precautionary statements	P210-P233-P280-P301+P312-P303+P361+P353-P305+P351+P338
Hazard Codes	C,Xn
Risk Statements	22-34
Safety Statements	26-36/37/39-45
RIDADR	UN 2920 3(8) / PGII
WGK Germany	3
HS Code	2905190098

Trifluoromethanesulfonic acid difluoromethyl ester Chemical Properties,Uses,Production

Uses

Difluoromethyl triflate (TfO-CHF₂) can be used as a reagent:

In difluoromethylation reaction.
To prepare difluoromethoxylated heterocycles by reacting with hydroxylated N-based heterocycles.
To synthesize trifluoromethylated arenes by treating with diaryliodonium salts in the presence of copper and tetrabutylammonium difluorotriphenylsilicate (TBAT).

It allows for a simple method toward the preparation of difluoromethyl ethers and thioethers under basic conditions from alcohols and thiols. Difluoromethyl phenols can also be obtained in a single pot from boronic acids and C-H activation of arenes.

General Description

Difluoromethyl triflate (HCF₂OTf) is an easy to handle, air-stable and non-ozone-depleting liquid reagent for difluoromethylation. It can be prepared by reacting trifluoromethyltrimethylsilane (TMSCF₃) and triflic acid in the presence of titanium tetrachloride (TiCl₄).

Trifluoromethanesulfonic acid difluoromethyl ester Preparation Products And Raw materials

Raw materials

3,3-Difluoro-3H-diazirine (Trifluoromethyl)trimethylsilane Trifluoromethanesulfonic acid (Difluoromethyl)trimethylsilane

Preparation Products

1,4-Bis(trifluoromethyl)-benzene 4-(TRIFLUOROMETHYL)DIPHENYL ETHER Dibenzothiophene Trifluoromethane Trimethylfluorosilane

3-(Difluoromethoxy)pyridine

chevron_left

1of2

chevron_right

Trifluoromethanesulfonic acid difluoromethyl ester Suppliers

Global( 49)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	China	10978	58	Inquiry
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	China	10260	58	Inquiry
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	China	12997	58	Inquiry
Shanghai Gubang New Materail Technology Co. LTD	21-51317962 +8618721305404	CHINA	272	58	Inquiry
Labnetwork lnc.	+86-27-50766799 +8618062016861	China	19994	58	Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	China	49739	58	Inquiry
LEAPCHEM CO., LTD.	+86-852-30606658	China	43348	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	57511	58	Inquiry
Suzhou ARTK Medchem Co., Ltd.	+8618168183658	China	39009	58	Inquiry
Henan Aochuang Chemical Co.,Ltd.	+86-0371-63689365 +8618638391208	China	9425	58	Inquiry

Supplier	Advantage
Zibo Hangyu Biotechnology Development Co., Ltd	58
Shenzhen Nexconn Pharmatechs Ltd	58
Zhengzhou Alfa Chemical Co.,Ltd	58
Shanghai Gubang New Materail Technology Co. LTD	58
Labnetwork lnc.	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
LEAPCHEM CO., LTD.	58
Aladdin Scientific	58
Suzhou ARTK Medchem Co., Ltd.	58
Henan Aochuang Chemical Co.,Ltd.	58

1885-46-7(Trifluoromethanesulfonic acid difluoromethyl ester)Related Search:

Trifluoromethanesulfonic acid Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester PHENYL TRIFLUOROACETATE TRIFLUOROACETALDEHYDE ETHYL HEMIACETAL Lithium trifluoromethanesulfonate

Nickel(II) Trifluoromethanesulfonate Sodium trifluoroacetate PRASEODYMIUM (III) TRIFLUOROMETHANESULFONATE MAGNESIUM TRIFLUOROMETHANESULFONATE NEODYMIUM(III) TRIFLUOROMETHANESULFONATE

Potassium trifluoroacetate GALLIUM(III) TRIFLUOROMETHANESULFONATE ERBIUM (III) TRIFLUOROMETHANESULFONATE Potassium trifluoromethanesulfonate Methyl trifluoroacetate

TRIFLUOROACETALDEHYDE HYDRATE

chevron_left

1of4

chevron_right

Trifluoromethanesulfonic acid difluoromethyl ester Difluoromethyl triflate 95% Difluoromethyl triflate Difluoromethyl trifluoromethanesulfonate Difluoromethyl trifluoromethanesulfonate 95% Methanesulfonic acid, 1,1,1-trifluoro-, difluoromethyl ester 1885-46-7 C2HF5O3S