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Bopindolol

Bopindolol Structure
CAS No.
62658-63-3
Chemical Name:
Bopindolol
Synonyms
Bopindolol;rac Bopindolol;Bopindolol USP/EP/BP;1-(tert-ButylaMino)-3-((2-Methyl-1H-indol-4-yl)oxy)propan-2-yl benzoate;2-[(1,1-Dimethylethyl)amino]-1-{[(2-methyl-1H-indol-4-yl)oxy]methyl}ethyl benzoate;1-[(1,1-DiMethylethyl)aMino]-3-[(2-Methyl-1H-indol-4-yl)oxy]-2-propanol 2-Benzoate;2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[(2-methyl-1H-indol-4-yl)oxy]-, 2-benzoate;2-PROPANOL, 1-[(1,1-DIMETHYLETHYL)AMINO]-3-[(2-METHYL-1H-INDOL-4-YL)OXY]-, BENZOATE (ESTER);(±)-1-[(1,1-DiMethylethyl)aMino]-3-[(2-Methyl-1H-indol-4-yl)oxy]-2-propanol Benzoate (Ester)
CBNumber:
CB8294403
Molecular Formula:
C23H28N2O3
Molecular Weight:
380.48
MOL File:
62658-63-3.mol
MSDS File:
SDS
Modify Date:
2023/5/4 17:34:40

Bopindolol Properties

Melting point 117-120°C
Boiling point 557.0±50.0 °C(Predicted)
Density 1.143±0.06 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
pka 17.59±0.30(Predicted)
form Solid
color White to Pale Beige

SAFETY

Risk and Safety Statements

Toxicity LD50 i.v. in mice: 17 mg/kg (Troxler, Seemann, 1977)

Bopindolol Chemical Properties,Uses,Production

Description

Bopindolol is a potent, long-acting, non-selective β-adrenergic blocker related to pindolol and useful in the treatment of hypertension. Unlike many other agents of this type, it appears to have negligible effects on serum lipoproteins.

Chemical Properties

Off-White to pale Yellow Solid

Uses

Bopindolol is an ester prodrug of Pindolol (P468000). Bopindolol is a long acting β-adrenoceptor blocking agent. Bopindolol displays antispasmogenic activity mediated by α1-adrenoceptors and 5-HT2 receptors.

Bopindolol Preparation Products And Raw materials

Global( 22)Suppliers
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CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 24200 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Angel Pharmatech, Ltd. 17317130613 China 3250 58 Inquiry
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TCI (Shanghai) Chemical Trading Co., Ltd. 021-021-61109150 China 31130 58 Inquiry
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Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 China 4658 58 Inquiry
A.T.CHEMICAL 0755-86655561 81899190 China 6594 51 Inquiry
AK Scientific, Inc. 650 494 8666 United States 6357 65 Inquiry
Bopindolol 2-PROPANOL, 1-[(1,1-DIMETHYLETHYL)AMINO]-3-[(2-METHYL-1H-INDOL-4-YL)OXY]-, BENZOATE (ESTER) 1-(tert-ButylaMino)-3-((2-Methyl-1H-indol-4-yl)oxy)propan-2-yl benzoate 2-[(1,1-Dimethylethyl)amino]-1-{[(2-methyl-1H-indol-4-yl)oxy]methyl}ethyl benzoate (±)-1-[(1,1-DiMethylethyl)aMino]-3-[(2-Methyl-1H-indol-4-yl)oxy]-2-propanol Benzoate (Ester) 1-[(1,1-DiMethylethyl)aMino]-3-[(2-Methyl-1H-indol-4-yl)oxy]-2-propanol 2-Benzoate rac Bopindolol 2-Propanol, 1-[(1,1-dimethylethyl)amino]-3-[(2-methyl-1H-indol-4-yl)oxy]-, 2-benzoate Bopindolol USP/EP/BP 62658-63-3 C23H28N2O3 Aromatics Heterocycles Indole Derivatives Inhibitors Intermediates & Fine Chemicals Pharmaceuticals