Famoxadone
- CAS No.
- 131807-57-3
- Chemical Name:
- Famoxadone
- Synonyms
- JE 874;Famoxate;CCharisma;Famoxadon;IN-JE 874;DPX-JE 874;FAMOXADONE;FaMoxadone solutio;famoxadone solution;famoxadone (bsi, pa iso)
- CBNumber:
- CB8439206
- Molecular Formula:
- C22H18N2O4
- Molecular Weight:
- 374.39
- MOL File:
- 131807-57-3.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/17 16:57:19
| Melting point | 140.3～141.8℃ |
|---|---|
| Boiling point | 491.3±55.0 °C(Predicted) |
| Density | 1.327±0.06 g/cm3(Predicted) |
| vapor pressure | 6.4 x 10-7 Pa (20 °C) |
| Flash point | 2 °C |
| storage temp. | 0-6°C |
| solubility | DMSO: 100 mg/mL (267.10 mM) |
| pka | 0.63±0.40(Predicted) |
| form | Solid:particulate/powder |
| Water Solubility | 0.243 mg-1 (pH 5), 0.011 mg l-1 (pH 7) at 20 °C |
| color | White to yellow |
| LogP | 4.65-5.08 at 20℃ and pH4-7 |
| Surface tension | 73mN/m at 90μg/L and 20.4℃ |
| EPA Substance Registry System | Famoxadone (131807-57-3) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|---|---|
| Signal word | Danger |
| Hazard statements | H225-H302-H312-H319-H332 |
| Precautionary statements | P210-P280-P305+P351+P338 |
| Hazard Codes | Xn,N,F |
| Risk Statements | 48/22-50/53-36-20/21/22-11 |
| Safety Statements | 46-60-61-36-26-16-36/37 |
| RIDADR | UN1648 3/PG 2 |
| WGK Germany | 2 |
| Toxicity | LD50 in rats (mg/kg): >5000 orally; >2000 dermally (Joshi, Sternberg) |
Famoxadone price More Price(2)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 33495 | Famoxadone solution 100?μg/mL in acetonitrile, PESTANAL?, analytical standard | 131807-57-3 | 2ML | ₹8498.7 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 33495 | Famoxadone solution 100?μg/mL in acetonitrile, PESTANAL?, analytical standard | 131807-57-3 | 2ML | ₹8498.7 | 2022-06-14 | Buy |
Famoxadone Chemical Properties,Uses,Production
Description
Famoxadone is an oxazolidinedione fungicide. Although famoxadone is not a strobilurin derivative, it shares the same mechanism of action. Famoxadone provides control of a broad spectrum of fungi but is particularly effective against downy mildew (P. viticola), late and early blights (Phytophthora infestans and Alternaria solani), the Septoria complex, and barley net blotch at rates of 50 to 200 g ai/ha. Target crops include vines, potatoes/tomatoes, cereals, sugar beets, canola, and cucumber. It shows good protectant, translaminar and residual control, with excellent rainfastness and good crop safety. As was seen for trifloxystrobin, it is particularly effective against grape downy mildew when applied in mixture with cymoxanil. The cereal disease spectrum and level of disease control are improved when famoxadone is mixed with triazole fungicides such as flusilazole.
Chemical Properties
Brown Solid
Uses
Famoxadone is a known fungicide used in the protection of agricultural products against various fungal diseases and other biotic stresses such as pests.
Agricultural Uses
Fungicide: Tanos 50-DF is recommended for use as a preventative fungicide for control of late blight and early blight on potatoes and field tomatoes.
Trade name
DPX-JE874®; FAMOXATE®; MEDLEY®; TANOS-50DF®
Pharmacology
Famoxadone inhibits activity of ubiquinol : cytochrome c oxidoreductase at the Qo site of complex III, the same target protein as the strobilurins (34,35). However, studies show a difference in the potency of various strobilurins compared with famoxadone in single amino acid mutants of the cytochrome b protein, suggesting that this compound may interact differently with the target protein (38).
Metabolic pathway
Famoxadone undergoes extensive degradation and metabolism in aqueous and soil environments, in wheat plants, rats, goats and hens via common pathways. The primary reactions include the hydrolytic opening of the oxazolidinedione ring, aryl hydroxylation, cleavage of the phenoxyphenyl and the oxazolidinedione-aminophenyl linkages and conjugation. More than 25 degradation products have been identified.
Famoxadone Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Qingdao Trust Agri Chemical Co.,Ltd | +8613573296305 | China | 267 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21669 | 55 | Inquiry |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | China | 9337 | 55 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29897 | 58 | Inquiry |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | China | 2141 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
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