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Isoacteoside

Isoacteoside Structure
CAS No.
61303-13-7
Chemical Name:
Isoacteoside
Synonyms
Isoacteosid;Isokusaginin;ISOACTEOSIDE;ISOVERBASCOSIDE;Isoacteoside, >=98%;Isoacteoside,HPLC≥98%;Isoacteoside (Isoverbascoside);3,4-Dihydroxyphenethyl 3-O-α-L-rhamnopyranosyl-6-O-(3,4-dihydroxycinnamoyl)-β-D-glucopyranoside;[(2R,3R,4S,5R,6R)-5-(3,4-Dihydroxyphenyl)-6-ethoxy-Chemicalbook3,5-dihydroxy-4-[(2S,3R,4R,5R,6S)-3;2-(3,4-Dihydroxyphenyl)ethyl 3-O-α-L-rhamnopyranosyl-6-O-(3,4-dihydroxycinnamoyl)-β-D-glucopyranoside
CBNumber:
CB8450300
Molecular Formula:
C29H36O15
Molecular Weight:
624.59
MOL File:
61303-13-7.mol
Modify Date:
2024/7/2 8:55:34

Isoacteoside Properties

Melting point 220~230℃
Boiling point 942.9±65.0 °C(Predicted)
Density 1.60±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility DMSO : ≥ 48 mg/mL (76.85 mM)
form Powder
pka 9.32±0.10(Predicted)
color White to yellow

SAFETY

Risk and Safety Statements

HS Code  29389090

Isoacteoside Chemical Properties,Uses,Production

Description

Isoverbascoside is a phenylethanoid glycoside that has been found in C. trichotomum and has diverse biological activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals in a cell-free assay and inhibits hydrogen peroxide-induced lipid peroxidation in V79-4 cells when used at a concentration of 10 μg/ml. Isoverbascoside (7.5-30 μM) induces apoptosis and production of reactive oxygen species (ROS) in, and reduces viability of, OVCAR-3 cells. It inhibits tumor growth in an OVCAR-3 mouse xenograft model when administered at a dose of 30 mg/kg. Isoverbascoside (2.5 and 5 mg/kg) decreases brain amyloid deposition and increases exploratory behavior in rats when infused into the cerebral ventricles with amyloid-β (1-42) (Aβ42; ). It also decreases xylene-induced ear edema in mice and increases survival in a mouse model of LPS-induced endotoxic shock.

Uses

Isoacteoside is a possible food antioxidant.

Isoacteoside Preparation Products And Raw materials

Raw materials

Preparation Products

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Isokusaginin Isoacteoside, >=98% β-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl 3-O-(6-deoxy-α-L-mannopyranosyl)-, 6-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate] ISOVERBASCOSIDE ISOACTEOSIDE Isoacteosid [(2R,3R,4S,5R,6R)-5-(3,4-Dihydroxyphenyl)-6-ethoxy-3,5-dihydroxy-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]methyl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate 2-(3,4-Dihydroxyphenyl)ethyl 3-O-(α-L-rhamnopyranosyl)-6-O-[(E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]-β-D-glucopyranoside 2-(3,4-Dihydroxyphenyl)ethyl 3-O-(α-L-rhamnopyranosyl)-6-O-[(E)-3-(3,4-dihydroxyphenyl)acryloyl]-β-D-glucopyranoside 2-(3,4-Dihydroxyphenyl)ethyl 3-O-α-L-rhamnopyranosyl-6-O-(3,4-dihydroxycinnamoyl)-β-D-glucopyranoside 3,4-Dihydroxyphenethyl 3-O-α-L-rhamnopyranosyl-6-O-(3,4-dihydroxycinnamoyl)-β-D-glucopyranoside Isoacteoside,HPLC≥98% Isoacteoside (Isoverbascoside) [(2R,3R,4S,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-3,5-dihydroxy-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]methyl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate ((2R,3R,4S,5R,6R)-6-(3,4-Dihydroxyphenethoxy)-3,5-dihydroxy-4-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)methyl (E)-3-(3,4-dihydroxyphenyl)acrylate [(2R,3R,4S,5R,6R)-5-(3,4-Dihydroxyphenyl)-6-ethoxy-Chemicalbook3,5-dihydroxy-4-[(2S,3R,4R,5R,6S)-3 61303-13-7 chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract