SR 12813

CAS No.: 126411-39-0

Chemical Name:: SR 12813

Synonyms: 1ilh;GW485801;GW 485801;GW-485801;SR12813;SR 12813;SR-12813(GW 485801);SR-12813, PXR agonist;SR12813, 10 mM in DMSO;SR-12813;SR12813;SR 12813;GW 485801;GW-485801;GW485801;4-[2,2-bis(diethoxyphosphoryl)ethenyl]-2,6-ditert-butylphenol

CBNumber:: CB8497376

Molecular Formula:: C24H42O7P2

Molecular Weight:: 504.53

MOL File:: 126411-39-0.mol

Modify Date:: 2025/1/27 9:38:02

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SR 12813 Properties

Melting point	119-121℃
Boiling point	552.6±50.0 °C(Predicted)
Density	1.117±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO: ≥10 mg/mL
form	solid
pka	9.95±0.70(Predicted)
color	White to off-white
biological source	synthetic (organic)

SAFETY

Risk and Safety Statements

WGK Germany	3
HS Code	29319090

SR 12813 price More Price(2)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	S4194	SR 12813 ≥98%, solid	126411-39-0	1MG	₹4319.18	2022-06-14	Buy
Sigma-Aldrich(India)	S4194	SR 12813 ≥98%, solid	126411-39-0	5MG	₹16984.43	2022-06-14	Buy

Product number	Packaging	Price	Buy
S4194	1MG	₹4319.18	Buy
S4194	5MG	₹16984.43	Buy

SR 12813 Chemical Properties,Uses,Production

Uses

SR 12813 is a pregnane X receptor (PXR, NR 112) agonist.

Definition

ChEBI: An organic phosphonate that is the tetraethyl ester of [2-(3,5-di-tert-butyl-4-hydroxyphenyl)ethene-1,1-diyl]bis(phosphonic acid).

Biological Activity

Pregnane X receptor (PXR) agonist (EC 50 values are 200 and 700 nM for human and rabbit PXR respectively). Activates the farnesoid X receptor (FXR) at μ M concentrations. Displays hypocholesterolaemic activity via enchanced degradation of HMG-CoA reductase.

SR 12813 Preparation Products And Raw materials

Raw materials

Preparation Products

SR 12813 Suppliers

Global( 70)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6257	58	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	33024	60	Inquiry
InvivoChem	+1-708-310-1919 +1-13798911105	United States	6391	58	Inquiry
TargetMol Chemicals Inc.		United States	38642	58	Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	China	8467	58	Inquiry
Aladdin Scientific		United States	57505	58	Inquiry
DC Chemicals	021-58447131 13564518121	China	9409	58	Inquiry
https://hanhongsci.com/	021-54306202 18917919676	China	29998	58	Inquiry
Guangzhou Isun Pharmaceutical Co., Ltd	020-39119399 18927568969	China	4720	55	Inquiry
Yantai Shengkailun Chemical Technology Co., Ltd.	13356901049	China	9311	58	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
ATK CHEMICAL COMPANY LIMITED	60
InvivoChem	58
TargetMol Chemicals Inc.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Aladdin Scientific	58
DC Chemicals	58
https://hanhongsci.com/	58
Guangzhou Isun Pharmaceutical Co., Ltd	55
Yantai Shengkailun Chemical Technology Co., Ltd.	58

126411-39-0(SR 12813)Related Search:

Benzoic acid, 4,5-difluoro-2-[[[6-(1H-imidazol-1-yl)-3-pyridazinyl]carbonyl]amino]- N-[2-[2-(Dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydro-1,4-benzodioxin-2-carboxamide SR9009 SR-9243 SR9011

N-((4,5-difluoro-1H-benzo[d]imidazol-2-yl)methyl)-9-(3-fluorophenyl)-2-morpholino-9H-purin-6-amine TETRAETHYL METHYLENEDIPHOSPHONATE DIETHYL ALLYLPHOSPHONATE DIMETHYL VINYLPHOSPHONATE METHYLENEDIPHOSPHONIC ACID

TETRAMETHYL METHYLENEDIPHOSPHONATE SR 12813 Tetraethyl vinylidene phosphonate, min. 97 % DIETHYL VINYLPHOSPHONATE

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[[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]ethenylidene]bis-phosphonicacidtetraethylester SR-12813(GW 485801) SR-12813;SR12813;SR 12813;GW 485801;GW-485801;GW485801 GW 485801 GW485801 GW-485801 SR12813;SR 12813 Phosphonic acid, P,P'-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]ethenylidene]bis-, P,P,P',P'-tetraethyl ester GW-485801,GW485801,HMG-CoA Reductase (HMGCR),Autophagy,SR12813,inhibit,Inhibitor Tetraethyl (2-(3,5-di-tert-butyl-4-hydroxyphenyl)ethene-1,1-diyl)bis(phosphonate) SR-12813, PXR agonist SR12813, 10 mM in DMSO 1ilh 4-[2,2-bis(diethoxyphosphoryl)ethenyl]-2,6-ditert-butylphenol 126411-39-0 C24H42O7P2