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SR 12813

SR 12813 Structure
  • ₹4319.18 - ₹16984.43
  • Product name: SR 12813
  • CAS: 126411-39-0
  • MF: C24H42O7P2
  • MW: 504.53
  • EINECS:
  • MDL Number:MFCD00888473
  • Synonyms:[[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]ethenylidene]bis-phosphonicacidtetraethylester;SR-12813(GW 485801);SR-12813;SR12813;SR 12813;GW 485801;GW-485801;GW485801;GW 485801;GW485801;GW-485801;SR12813;SR 12813;Phosphonic acid, P,P'-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]ethenylidene]bis-, P,P,P',P'-tetraethyl ester
Price2 Properties Safety Information Description
2 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 1MG
  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberS4194
  • Product descriptionSR 12813 ≥98%, solid
  • Packaging5MG
  • Price₹16984.43
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberS4194
  • Product descriptionSR 12813 ≥98%, solid
  • Packaging1MG
  • Price₹4319.18
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) S4194 SR 12813 ≥98%, solid 5MG ₹16984.43 2022-06-14 Buy
Sigma-Aldrich(India) S4194 SR 12813 ≥98%, solid 1MG ₹4319.18 2022-06-14 Buy

Properties

Melting point :119-121℃
Boiling point :552.6±50.0 °C(Predicted)
Density :1.117±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO: ≥10 mg/mL
form :solid
pka :9.95±0.70(Predicted)
color :White to off-white
biological source :synthetic (organic)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

SR-12813 is a 1,1-bisphosphonate ester that exhibits hypocholesterolemic activity by enhancing the degradation of HMG-CoA reductase in various animal models. SR-12813 is also a high affinity ligand for human and rabbit pregnane X receptors (Kd = 41 nM; EC50 = 137 nM for hPXR in vitro) and can induce cytochrome P450 3A expression in human and rabbit hepatocytes.

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