SR9009
|
- ₹15910
- Product name: SR9009
- CAS: 1379686-30-2
- MF: C20H24ClN3O4S
- MW: 437.94
- EINECS:1592732-453-0
- MDL Number:MFCD29472236
- Synonyms:SR9009;3-[[[(4-Chlorophenyl)methyl][(5-nitro-2-thienyl)methyl]amino]methyl]-1-pyrrolidinecarboxylic acid ethyl ester;ethyl-3-(((4-chlorobenzyl)((5-nitrothiophen-2-yl)methyl)amino)methyl)pyrrolidine-1-carboxylate;SR9009 sarms,whnohe_lucy(at)163.com;Ethyl 3-[[[(4-chlorophenyl)methyl][(5-nitro-2-thienyl)methyl]amino]methyl]-1-pyrrolidinecarboxylate;CS-2027;SR9009 Powder whnohe_carolineat163.com;Stenabolic (SR9009)
1 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product number554726
- Product descriptionREV-ERB Agonist II, SR9009 - Calbiochem The REV-ERB Agonist II, SR9009 controls the biological activity of REV-ERB. This small molecule/inhibitor is primarily used for Biochemicals applicati
- Packaging25MG
- Price₹15910
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 554726 | REV-ERB Agonist II, SR9009 - Calbiochem The REV-ERB Agonist II, SR9009 controls the biological activity of REV-ERB. This small molecule/inhibitor is primarily used for Biochemicals applicati | 25MG | ₹15910 | 2022-06-14 | Buy |
Properties
Melting point :79-81°C
Boiling point :547.2±45.0 °C(Predicted)
Density :1.327±0.06 g/cm3(Predicted)
storage temp. :-20°
solubility :Soluble in DMSO (greater than 25 mg/ml) or in Ethanol (up to 20 mg/ml).
form :solid
pka :6.12±0.50(Predicted)
color :Tan
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
InChI :InChI=1S/C20H24ClN3O4S/c1-2-28-20(25)23-10-9-16(13-23)12-22(11-15-3-5-17(21)6-4-15)14-18-7-8-19(29-18)24(26)27/h3-8,16H,2,9-14H2,1H3
InChIKey :MMJJNHOIVCGAAP-UHFFFAOYSA-N
SMILES :N1(C(OCC)=O)CCC(CN(CC2=CC=C(Cl)C=C2)CC2SC([N+]([O-])=O)=CC=2)C1
Boiling point :547.2±45.0 °C(Predicted)
Density :1.327±0.06 g/cm3(Predicted)
storage temp. :-20°
solubility :Soluble in DMSO (greater than 25 mg/ml) or in Ethanol (up to 20 mg/ml).
form :solid
pka :6.12±0.50(Predicted)
color :Tan
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
InChI :InChI=1S/C20H24ClN3O4S/c1-2-28-20(25)23-10-9-16(13-23)12-22(11-15-3-5-17(21)6-4-15)14-18-7-8-19(29-18)24(26)27/h3-8,16H,2,9-14H2,1H3
InChIKey :MMJJNHOIVCGAAP-UHFFFAOYSA-N
SMILES :N1(C(OCC)=O)CCC(CN(CC2=CC=C(Cl)C=C2)CC2SC([N+]([O-])=O)=CC=2)C1
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
REV-ERBα and REV-ERBβ nuclear receptors are transcriptional repressors that coordinate circadian rhythm and metabolic pathways in a heme-dependent manner. SR9009 is a REV-ERB agonist that increases the constitutive repression of genes regulated by REV-ERBα and REV-ERBβ with IC50 values of 670 and 800 nM, respectively. Through activation of REV-ERB, SR9009 has been shown to decrease circadian locomotor activity during the dark phase and to alter the expression pattern of core clock genes in the hypothalami of mice. The circadian pattern of expression of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also shown to be altered in mice exposed to SR9009, resulting in increased energy expenditure. Diet-induced obese mice treated with 100 mg/kg SR9009 (i.p. two times a day for 30 days) have been reported to display decreased fat mass and markedly improved dyslipidemia and hyperglycemia.More related product prices
N-((4,5-difluoro-1H-benzo[d]imidazol-2-yl)methyl)-9-(3-fluorophenyl)-2-morpholino-9H-purin-6-amine SR9011 SR-9243 1072959-67-1 SR 12813 SR17018 SR27897 SR 0987 N-[2-[3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-2-quinoxalinecarboxamide SR 1078 SRPK inhibitor SR8278 STRONTIUM 2-Chloro-N-(6-methoxy-4-quinolinyl)-5-nitrobenzamideRelated product price
- SR 12813
₹4319.18-16984.43 - N-[2-[3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-2-quinoxalinecarboxamide
₹29860 - SRPK inhibitor
₹11009.03-44339.2
Suppliers and manufacturers
Powerhouse Nutritions Private Limited
City Cat Overseas Chemicals Limited
Healthster Co.
Kapil Enterprises
A.J Chemicals
Changzhou Xuanming Pharmaceutical Technology Co., Ltd.
Zhejiang J&C Biological Technology Co.,Limited
