ChemicalBook > Product Catalog >Biochemical Engineering >Nucleoside drugs >Deoxynucleotides and their analogs >2'-Deoxy-2'-fluorocytidine

2'-Deoxy-2'-fluorocytidine

2'-Deoxy-2'-fluorocytidine Structure
CAS No.
10212-20-1
Chemical Name:
2'-Deoxy-2'-fluorocytidine
Synonyms
2'-FC;2'-FdC;RO-8013;2'-F-dC;2'-FANA-C;NSC 529432;2’-F-2’-dC;2'-FLUORO-D-CYTIDINE;2'-F-2'-deoxyCytidine;2'-F-2'-deoxycytidine
CBNumber:
CB8670324
Molecular Formula:
C9H12FN3O4
Molecular Weight:
245.21
MOL File:
10212-20-1.mol
Modify Date:
2024/7/24 10:07:30

2'-Deoxy-2'-fluorocytidine Properties

Melting point 167 °C
Boiling point 500.1±60.0 °C(Predicted)
Density 1.82±0.1 g/cm3(Predicted)
refractive index 80 ° (C=1, MeOH)
storage temp. Keep in dark place,Sealed in dry,2-8°C
solubility Soluble in DMSO, Methanol.
pka 12.84±0.70(Predicted)
form Powder
color White to Off-white
Water Solubility Water: 5 mg/mL (20.39 mM; ultrasonic and warming and heat to 60°C)
InChI InChI=1S/C9H12FN3O4/c10-6-7(15)4(3-14)17-8(6)13-2-1-5(11)12-9(13)16/h1-2,4,6-8,14-15H,3H2,(H2,11,12,16)/t4-,6-,7-,8-/m1/s1
InChIKey NVZFZMCNALTPBY-XVFCMESISA-N
SMILES OC[C@H]1O[C@@H](N2C=CC(N)=NC2=O)[C@H](F)[C@@H]1O
CAS DataBase Reference 10212-20-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
HS Code  29389090

2'-Deoxy-2'-fluorocytidine price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemicals (India) D3614 2'-Deoxy-2'-fluorocytidine 10212-20-1 1G ₹4300 2022-05-26 Buy
Product number Packaging Price Buy
D3614 1G ₹4300 Buy

2'-Deoxy-2'-fluorocytidine Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

2'-Deoxy-2'-fluorocytidine is a potent inhibitor of the subgenomic hepatitis C virus replicon in Huh-7 cells. 2'-Deoxy-2'-fluorocytidine has been shown to inhibit Borna Disease virus replication and s pread.

in vitro

2'-Deoxy-2'-fluorocytidine has antiviral activities, showing 50% effective concentrations (EC50) of 61 nM and 31 nM against CCHFV and CCHFV/ZsG in Huh7 cells, respectively. And it shows a 50% cytotoxicity concentration (CC50) of >50.0 μM in Huh7 cells.

References

[1] Stephen R. Welch. “Identification of 2′-deoxy-2′-fluorocytidine as a potent inhibitor of Crimean-Congo hemorrhagic fever virus replication using a recombinant fluorescent reporter virus.” Antiviral research 147 (2017): Pages 91-99.

2'-Deoxy-2'-fluorocytidine Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 312)Suppliers
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A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
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TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
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Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
4-amino-1-[(2r,3r,4r,5r)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one 4-AMINO-1-((2R,3R,4R,5R)-3-FLUORO-4-HYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-2-YL)-1H-PYRIMIDIN-2-ONE 2'-FLUORO-D-CYTIDINE 2'-DEOXY-2'-FLUOROCYTIDINE 2'-FC 2'-FLUORO-2'-DEOXYCYTIDINE 2'-FdC 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)cytosine 1-(2-Fluoro-2-deoxy-β-D-arabinofuranosyl)cytosine RO-8013 2'-DEOXY-2'-FLUOROCYTIDINE(2'-FLUORO-2'- DEOXYCYTIDINE, 2'-FC) 2'-Deoxy-2'-fluoro-D-cytidine 2''-DEOXY-2''-FLUOROCYTIDINE,99+% 2'-Deoxy-2'-fluorocytidine Hydrate 2'-Deoxy-2'-fluorocytidine ,98% 2'-Fluoro-2'-deoxy-β-D-ribofuranosylcytosine FN-009 2'-Fluoro-2'-deoxy-cytidine Cytidine, 2'-deoxy-2'-fluoro- 2'-FANA-C NSC 529432 2'-Deoxy-2'-fluorocytidine  2'-Deoxy-2'-fluorocytidine≥ 99% (HPLC) Fludarabine Phosphate Impurity 18 2'-Fluoro-2'-deoxycytidine, >98.0%(T) 2'-Deoxy-2'-fluorocytidineHydrate> 2’-F-2’-dC 4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one USP/EP/BP 4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl... 2'-F-2'-deoxyCytidine Crimean-Congo hemorrhagic fever,2' Deoxy 2' fluorocytidine,Inhibitor,nucleoside analog,inhibit,Influenza Virus,2'Deoxy2'fluorocytidine,Antiviral,CCHFV 2'-Fluoro-2'-Deoxycytidine (FdC) 4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one 2'-Fluoro-2'-Deoxycytidine 2'-Deoxy-2"-fuorocytidine 2'-F-2'-deoxycytidine 2'-Deoxy-2'-fluorocytidine 2'-F-dC 10212-20-1 110212-20-1 C9H12FN3O4xH2O C9H12N3O4F C9H12FN3O4 Biochemistry Nucleosides and their analogs Nucleosides, Nucleotides & Related Reagents 10212-20-1 Nucleosides Modified(deoxy)nucleoside Nucleosides-2'-F Nucleosides