Bilirubin
- CAS No.
- 635-65-4
- Chemical Name:
- Bilirubin
- Synonyms
- Cholerythrin;BILIRUBIN MIXED ISOMERS;Biliyubin;Bilibubin;filirubin;BILIRUBIN;hemetoidin;HEMATOIDIN;1,19-dioxo-;BilirubinGr
- CBNumber:
- CB8693422
- Molecular Formula:
- C33H36N4O6
- Molecular Weight:
- 584.66
- MOL File:
- 635-65-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/12 17:17:06
| Melting point | 192 °C |
|---|---|
| Boiling point | 641.7°C (rough estimate) |
| Density | 1.2163 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| storage temp. | -20°C |
| solubility | aqueous acid: soluble |
| form | powder |
| pka | 4.62±0.10(Predicted) |
| color | orange |
| Water Solubility | practically insoluble |
| Sensitive | Light Sensitive |
| Merck | 14,1218 |
| BRN | 74376 |
| Stability | Stable. Refrigerate. |
| EPA Substance Registry System | Bilirubin (635-65-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 62-36/37/38-20/21/22 | |||||||||
| Safety Statements | 22-24/25-36-26 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | DU3038000 | |||||||||
| F | 8 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29339990 | |||||||||
| NFPA 704 |
|
Bilirubin price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | B4126 | Bilirubin ≥98% (EmM/453 = 60), powder | 635-65-4 | 1G | ₹14949.33 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | B4126 | Bilirubin ≥98% (EmM/453 = 60), powder | 635-65-4 | 5G | ₹53464.68 | 2022-06-14 | Buy |
| Sigma-Aldrich | 14370 | Bilirubin purum, ≥95.0% (UV) | 635-65-4 | 250MG | ₹5661.48 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 14370 | Bilirubin purum, ≥95.0% (UV) | 635-65-4 | 250MG | ₹5661.48 | 2022-06-14 | Buy |
| Sigma-Aldrich | 14370 | Bilirubin purum, ≥95.0% (UV) | 635-65-4 | 1G | ₹14624.58 | 2022-06-14 | Buy |
Bilirubin Chemical Properties,Uses,Production
Description
Bilirubin is a yellow breakdown product of heme catabolism, formed when heme is cleaved by heme oxygenase. This reaction produces carbon monoxide and biliverdin, which is rapidly reduced to bilirubin by biliverdin reductase. Bilirubin has key roles as a free radical scavenger with antioxidant and anti-inflammatory actions. Free and albumin-bound bilirubin can also scavenge nitric oxide (NO) and NO-related species. Unconjugated bilirubin is highly water-insoluble and must be conjugated with glucuronides to become water soluble and subsequently excreted by the liver and kidney.
Chemical Properties
Light Orange to Deep Redish-Brown Crystalline Solid
Uses
Bilirubin is widely utilized to monitor the liver function and their disease, such as hepatitis or cirrhosis; or the effects of medicines which are damage the liver. It acts as a pigment in certain algae to capture light energy. Its double bonds are isomerizes in the presence of light, which is employed in phototherapy of jaundiced newborns babies. It is used to detect the blocking in bile ducts.
Definition
Red coloring matter of bile. Also occurs in blood serum as decomposition product of hemoglobin.
General Description
Bilirubin, a heme catabolism end-product is produced by the reduction of its metabolic precursor biliverdin by the action of enzyme biliverdin reductase.
Purification Methods
An acyclic tetrapyrrole bile pigment with impurities which can be eliminated by successive Soxhlet extraction with diethyl ether and MeOH. It crystallises from CHCl3 as deep red-brown rhombs, plates or orange-red prisms from chlorobenzene (m 330o dec) and is dried to constant weight at 80o under vacuum. [Gray et al. J Chem Soc 2264, 2276 1961, Beilstein 26 III/IV 3268.]
Bilirubin Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| GLR Innovations | +91 9891111994 | New Delhi, India | 4542 | 58 | Inquiry |
| Dr. Silviu Pharmachem Pvt., Ltd. | +91-8390608382 +91-8390608382 | Mumbai, India | 248 | 58 | Inquiry |
| Loba Chemie Pvt Ltd | +91-22-6663 6663 | Mumbai, India | 498 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| 5 E Scientific | 91-22-28016026 | Maharashtra, India | 137 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Anand Agencies | 91-20-24454597 | Maharashtra, India | 2337 | 58 | Inquiry |
| Arun & Co. | 91-22-67723000 | Maharashtra, India | 15 | 58 | Inquiry |
| Kemona Impex | 08068441141Ext 577 | Mumbai, India | 221 | 58 | Inquiry |
| Kiran Lights Laboratories | 91-9987701501 | Maharashtra, India | 262 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| GLR Innovations | 58 |
| Dr. Silviu Pharmachem Pvt., Ltd. | 58 |
| Loba Chemie Pvt Ltd | 58 |
| Pharma Affiliates | 58 |
| 5 E Scientific | 58 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| Anand Agencies | 58 |
| Arun & Co. | 58 |
| Kemona Impex | 58 |
| Kiran Lights Laboratories | 58 |
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