Nicaraven
- CAS No.
- 79455-30-4
- Chemical Name:
- Nicaraven
- Synonyms
- AVS;NICARAVEN;Nicaraven, >98%;Nicaraven, 79455-30-4;1,2-bis(nicotinamido)propane;n,n'-propylenedinicotinamide;N,N'-Propylenebisnicotinamide;N,N'-Propylenebis(nicotinamide);N,N'-(Propane-1,2-diyl)dinicotinaMide;N,N'-(1-Methylethylene)bisnicotinamide
- CBNumber:
- CB8841557
- Molecular Formula:
- C15H16N4O2
- Molecular Weight:
- 284.31
- MOL File:
- 79455-30-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:39
| Melting point | 156-157° |
|---|---|
| Boiling point | 635.9±40.0 °C(Predicted) |
| Density | 1.213±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | DMF: 5 mg/ml; DMSO: 10 mg/ml; Ethanol: 2 mg/ml; PBS (pH 7.2): 2 mg/ml |
| form | A crystalline solid |
| pka | 12.93±0.46(Predicted) |
| color | White to off-white |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
| NFPA 704 |
|
Nicaraven Chemical Properties,Uses,Production
Description
Nicaraven is an antioxidant that exhibits hydroxyl radical scavenging activity in vitro. Nicaraven (1-3 mg/kg per min, i.v.) reduces occurrence of chronic cerebral vasospasms in a dose-dependent manner in a canine model of subarachnoid hemorrhage. In a canine model of warm hepatic ischemia and reperfusion injury, nicaraven (2 mg/kg per min, i.v.) reduces liver enzyme release and inhibits lipid peroxidation and neutrophil infiltration in the liver. Nicaraven (100 mg/kg per day, i.p.) also decreases plasma levels of the inflammatory cytokines Il-6 and Tnf-α and the urinary levels of 8-oxo-2''-deoxyguanosine, a marker of DNA oxidation, in a mouse model of radiation-induced injury.
Nicaraven Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 102)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29898 | 58 | Inquiry |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | CHINA | 21149 | 58 | Inquiry |
| InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418684 +8618949823763 | China | 25363 | 58 | Inquiry |
| Coresyn Pharmatech Co., Ltd. | +86-571-86626709 +86-18157142896 | China | 9991 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 | United States | 19973 | 58 | Inquiry |
| Hu Bei Jiutian Bio-medical Technology CO.,Ltd | 027-88013699 17354350817 | China | 7431 | 58 | Inquiry |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | China | 11681 | 58 | Inquiry |
79455-30-4(Nicaraven)Related Search:
Nicotinamide
N-Isopropylacrylamide
POLY(N-ISOPROPYL ACRYLAMIDE)
POLYAMINOPROPYL BIGUANIDE
Safinamide mesylate
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1of3
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n,n'-propylenedinicotinamide
NICARAVEN
1,2-bis(nicotinamido)propane
AVS
N,N'-(1-Methylethylene)bis(pyridine-3-carboxamide)
N,N'-(1-Methylethylene)bisnicotinamide
N,N'-Propylenebis(nicotinamide)
N,N'-Propylenebisnicotinamide
N,N'-(Propane-1,2-diyl)dinicotinaMide
3-Pyridinecarboxamide,N,N'-(1-methyl-1,2-ethanediyl)bis-
Nicaraven N,N'-Propylenedinicotinamide
Nicaraven, 79455-30-4
N-{1-[(pyridin-3-yl)formamido]propan-2-yl}pyridine-3-carboxamide
Nicaraven, >98%
N-N'-(1-Methyl-1,2-ethanediyl)bis-3-pyridinecarboxamide
Nicaraven/AVS, Antevas,1,2-Bis(nicotinamido)propane
79455-30-4
9455-30-4
Inhibitors