Salinomycin
- CAS No.
- 53003-10-4
- Chemical Name:
- Salinomycin
- Synonyms
- SALINOMYCIN SODIUM;SALINOMYCIN SODIUM SALT;coxistac;Procoxacin;Salinomycin;SALINOMYCIN 90%;Antibiotic-61477;Salinomycin, >98%;SalinoMycin 12% 24%;SALINOMYCIN GRANULE
- CBNumber:
- CB9161784
- Molecular Formula:
- C42H70O11
- Molecular Weight:
- 751
- MOL File:
- 53003-10-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/24 13:33:21
| Melting point | 112.5-113.5 °C(lit.) |
|---|---|
| Boiling point | 839.2±65.0 °C(Predicted) |
| alpha | D25 -63° (c = 1 in ethanol) |
| Density | 1.18±0.1 g/cm3(Predicted) |
| Flash point | >110°(230°F) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | insoluble in H2O; ≥142.2 mg/mL in EtOH; ≥91.8 mg/mL in DMSO |
| pka | 6.4 (DMF) |
| form | White solid |
| color | White to light yellow |
| Water Solubility | Soluble in methanol. Insoluble in water |
| Merck | 13,8415 |
| Stability | Stable, but may be heat sensitive - keep cool. Incompatible with strong oxidizing agents. |
| LogP | 5.596 (est) |
| CAS DataBase Reference | 53003-10-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H300 | |||||||||
| Precautionary statements | P264-P270-P301+P310-P405-P501 | |||||||||
| Hazard Codes | T,Xi | |||||||||
| Risk Statements | 25-36/37/38 | |||||||||
| Safety Statements | 45-36-26 | |||||||||
| RIDADR | UN 3462 6.1/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | VO8620000 | |||||||||
| F | 10 | |||||||||
| HazardClass | 6.1(a) | |||||||||
| PackingGroup | II | |||||||||
| Toxicity | LD50 in mice (mg/kg): 18 i.p.; 50 orally (Miyazaki) | |||||||||
| NFPA 704 |
|
Salinomycin price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | S4526 | Salinomycin from Streptomyces albus, ≥98% (HPLC) | 53003-10-4 | 5MG | ₹21249.48 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S4526 | Salinomycin from Streptomyces albus, ≥98% (HPLC) | 53003-10-4 | 25MG | ₹64268.03 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S4526 | Salinomycin from Streptomyces albus, ≥98% (HPLC) | 53003-10-4 | 50MG | ₹119226.55 | 2022-06-14 | Buy |
Salinomycin Chemical Properties,Uses,Production
Description
Salinomycin was found in the culture mycelium of Streptomyces albus by Otake et al. of the University of Tokyo in 1973. Like other polyether ionophore antibiotics, it shows activity against gram-positive bacteria, fungi, and Coccidium. Salinomycin has been used as a feed additive to protect poultry against coccidial infections.
Chemical Properties
solid
Uses
Salinomycin is a polyether ionophore with broad spectrum Gram positive and anti-coccidial activity. Salinomycin has a high affinity for monovalent cations, particularly potassium. Salinomycin is used to control coccidia in animals and for growth promotion in ruminants. Recently, salinomycin has been shown to inhibit cancer stem cells and is >100 times more potent than taxol. While the mechanism of action is unknown, it was noted that among the 60,000 compounds screened, another monovalent ionophore, nigericin, and a chloride channel inhibitor, avermectin, were also active.
General Description
Chemical structure: polyether
Salinomycin Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 254)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Hebei Guanlang Biotechnology Co,.LTD | +86-19930503253; +8619930503252 | China | 5835 | 58 | Inquiry |
| shandong perfect biotechnology co.ltd | +86-53169958659; +8618596095638 | China | 294 | 58 | Inquiry |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618740459177 | China | 1142 | 58 | Inquiry |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21669 | 55 | Inquiry |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | China | 2141 | 58 | Inquiry |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | China | 6387 | 58 | Inquiry |
53003-10-4(Salinomycin)Related Search:
chevron_left
1of4
chevron_right
coxistac
SALINOMYCIN GRANULE
Salinomycin Premix 12%
SALINOMYCIN FROM STREPTOMYCES ALBUS
SALINOMYCIN 90%
SV sodium salt,2,5 salinomycin hydrate
(2R)-2-((5S)-6-{5-[(10S,12R)-2-((6S,5R)-5-Ethyl-5-hydroxy-6-methylperhydro-2H-pyran-2-yl)-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[4.1.5.3]pentadec-13-en-9-yl](1S,2S,3S,5R)-2-hydroxy-1,3-dimethyl-4-oxoheptyl}-5-methylperhydro-2H-pyran-2-yl)butanoic acid
Salinomycin
Antibiotic-61477
SalinoMycin(Procoxacin)
SalinoMycin 12% 24%
Procoxacin
Eustin, AHR 3096, K 364, 61477
Salinomycin Solution, 100ppm
Salinomycin, >98%
Salinomycin USP/EP/BP
SALINOMYCIN SODIUM PREMIX （10%, 12%, 45%）
99% purity Salinomycin
Salinomycin (10mM in DMSO)
(R)-2-((2R,5S,6R)-6-((2S,3S,4S,6R)-6-((2S,5S,7R,9S,10S,12R,15R)-2-((2R,5R,6S)-5-Ethyl-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[4.1.57.35]pentadec-13-en-9-yl)-3-hydroxy-4-methyl-5-oxooctan-2-yl)-5-methyltetrahydro-2H-pyran-2-yl)butanoic acid
(R)-2-((2R,5S,6R)-6-((2S,3S,4S,6R)-6-((2S,5S,7R,9S,10S,12R,15R)-2-((2R,5R,6S)-5-Ethyl-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[4.1.57.35]pentadec-13-en-9-yl)-3-hydroxy-4-methyl-5-oxooctan-2-yl)-5-methylt
SalinomycinQ: What is
Salinomycin Q: What is the CAS Number of
Salinomycin Q: What is the storage condition of
Salinomycin Q: What are the applications of
Salinomycin
SALINOMYCIN SODIUM
SALINOMYCIN SODIUM SALT
53003-10-4
C42H69NaO11
C42H69O11Na
C42H70O11
Antibiotics N-S
Antibiotics A to Z
Antibiotics
BioChemical
KOKCISAN
Antibacterial
Antibiotics
Antibiotics A to
Antibiotics N-SAntibiotics
Chemical Structure Class
L - ZAntibiotics
Mechanism of Action
Monovalent Ion Channels
Polyethers
Inhibitors
Interferes with Cell Membrane Permeability (Ionophores)Voltage-gated Ion Channels
IonophoresSpectrum of Activity
53003-10-4