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DMT-2μ-O-Me-rG(ib) amidite

DMT-2μ-O-Me-rG(ib)  amidite Structure
CAS No.
251647-55-9
Chemical Name:
DMT-2μ-O-Me-rG(ib) amidite
Synonyms
DMT-2'-O-MOE-G(iBu)-CE;2’-MOE-dG(iBu) Amidite;DMT-2'-O-MOE-G(iBu)-CEP;DMT-2'-O-MOE-G(iBu)-CEP;DMT-2μ-O-Me-rG(ib) amidite;N2-iBu-5'-O-DMT-2'-O-MOE-G-CE;2'-O-MOE-ibu-G Phosphoramidite;2'-MOE-N-iBu Guanosine Amidite;2'-MOE-iBu-G CE Phosphoramidite;2'-MOE-iBu-G CE Phosphoramidite
CBNumber:
CB92092206
Molecular Formula:
C47H60N7O10P
Molecular Weight:
913.99
MOL File:
251647-55-9.mol
Modify Date:
2023/12/15 10:01:10

DMT-2μ-O-Me-rG(ib) amidite Properties

storage temp. 4°C, protect from light
solubility DMSO : 250 mg/mL (273.53 mM; Need ultrasonic)
form Powder
pka 9.16±0.20(Predicted)
color White to Off-white
InChIKey LADCDGNEBIQAAU-KEFUZROQNA-N

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

DMT-2μ-O-Me-rG(ib) amidite Chemical Properties,Uses,Production

Description

Nucleoside phosphoramidites are used in the synthesis of oligonucleotides. Using a chemical approach allows quick and inexpensive access to custom-made oligonucleotides of the desired sequence. Enzymatic synthesis proceeds in a 5’ to 3’ direction, however the chemical synthesis is usually performed in the opposite direction. 5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite, also known as DMT-2μ-O-Me-rG(ib) amidite, is a modified guanosine with a 2’-O-(2-methoxyethyl) group, these have been used in the synthesis of oligonucleotides as antisense drugs.

Uses

5''-O-DMT-N2-isobutyryl-2''-O-(2-methoxyethyl)-guanosine 3''-CE phosphoramidite (CAS# 251647-55-9) is a nucleotide, and a derivative of guanosine, and is used in the stereochemical sythesis of phosphorothioate oligonucleotides.

storage

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

DMT-2μ-O-Me-rG(ib) amidite Preparation Products And Raw materials

Raw materials

Preparation Products

DMT-2μ-O-Me-rG(ib) amidite Suppliers

Global( 119)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Innovassynth Technologies (I) Ltd. +91-2192260100 +91-7208872197 Maharashtra, India 118 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Allbiosyn Biotechnology Co.,Ltd. +8618666985712 China 286 58 Inquiry
Shanghai Daken Advanced Materials Co.,Ltd +86-371-66670886 China 16208 58 Inquiry
Shenzhen Nexconn Pharmatechs Ltd +86-755-89396905 +86-15013857715 China 10318 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
NewCan Biotech Limited +86-0571-86912261 +8613735419629 China 9980 58 Inquiry
Zhejiang Hengkang Pharmaceutical Co., Ltd. +86-576-83372028 +86-18868723926 China 119 58 Inquiry
Wuhu Nuowei chemistry Co., Ltd. +86-0553-2911116-802 +undefined17756524438 China 1640 58 Inquiry
DMT-2μ-O-Me-rG(ib) amidite 5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine 3'-CE phosphoramidite Guanosine, 5'-O-[bis(4-Methoxyphenyl)phenylMethyl]-2'-O-(2-Methoxyethyl)-N-(2-Methyl-1-oxopropyl)-, 3'-[2-cyanoethyl bis(1-Methylethyl)phosphoraMidite] 2'-MOE-G(iBu)-3'-phosphoramidite 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)guanosine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-O-methylguanosine-3'-(2-cyanoethyl diisopropylphosphoramidite) GUANOSINE, 5'-O-[BIS(4-METHOXYPHENYL)PHENYLMETHYL]-2'-O-(2-METHOXYETHYL)-N-(2-METHYL-1-OXOPROPYL)-, 3'-[2-CYANOETHYL BIS(1-METHYLETHYL)PHOSPHORAMIDITE] (9CI) 2'-O-MOE-ibu-G Phosphoramidite 5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite 2'-O-MOE-G(iBu)-CE Phosphoramidite DMT-2'-O-MOE-G(iBu)-CEP DMT-2'-O-MOE-G(iBu)-CE-Phosphoramidite N2-isobutyryl-5'-O-(4, 4'-dimethoxytrityl)-2'-O- methoxyethyl-guanosine-3'-cyanoethyl Phosphoramidite Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] 5’-O-(4,4’-Dimethoxy-trityl)-N2-iso-butyroyl-2’-O-(2-methoxyethyl)guanosine-3’-O-[(2-cyanoethyl)(N,N-diisopropyl)]-phosphoramidite 5'-O-DMT-N2-isobutyryl-2'-O-?methoxyethylguanosine 3'-CE phosphoramidite N2-isobutyryl-5'-O-DMT-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite 2'-O-MOE-rG(ibu) Phosphoramidite 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methoxyethyl-N2-isobutyryl- guanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite 5'-O-DMT-2’-MOE-N2-iBu-Guanosine-CE-Phosphoramidite DMT-2′O-MOE-rG(ib) Phosphoramidite 2’-MOE-G(iBu)-3’-phospho ramidite 5’-O-(4,4’-Dimethoxy-trityl)-N2-iso-butyroyl-2’-O-(2-methoxyethyl)guanosine-3’-O-[(2-cyanoethyl)(N,N-diisopropyl)]-phosphoramidite 5'-O-DMT-2'-MOE-N2-Isobutyryl-Guanosine-CE Phosphoramidite 5’-O-DMTr-N2-iBu-2’-O-MOE-guanosine-3’-CED phosphoramidite N2-iBu-5'-O-DMT-2'-O-MOE-G-CE 2'-MOE-iBu-G CE Phosphoramidite 5'-O-DMT-2'-O-MOE- N2-Isobutyryl- Guanosine -3’-Cyanoethyl Phosphoramidite DMT-2'-O-MOE-G(iBu)-CE-PhosphoramiditeN2-isobutyryl-5'-O-(4,4'-dimethoxytri-tyl)-2'-O-methoxyethyl-guanosine-3'-cya-noethyl Phosphoramidite 2'-MOE-N-iBu Guanosine Amidite DMT-2'-O-MOE-G(iBu)-CE [5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-N6-benzoyladenosin-3'-O-yl]-2-cyanoethyl-N,N-diisopropylphosphoramidite DMTr-2'-O-MOE-rG(iBu)-3'-CE-Phosphoramidite 2’-MOE-dG(iBu) Amidite Guanosine, 5-o-bis(4-methoxyphenyl)phenylmethyl-2-o-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)-, 3-2-cyanoethyl bis(1- 5’-O-(4, 4’-Dimethoxytrityl)-N2-isobutyryl-2’-O-(2-methoxyethyl)guanosine-3’-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite 5'-ODMT-2'-OMOE-N-iBu Guanosine-3'-OCEPA DMT-2'-O-MOE-G(iBu)-CE Phosphoramidite 2’-MOE-G(iBu)-3’-phosphoramidite 5'-O-DMT-2'-MOE-N2-Isobutyryl-Guanosine-CE Phosphoramidite 2'-MOE-iBu-G CE Phosphoramidite 2'-O-MOE-G(iBu)-CE-Phosphoramidite 5’-O-(4, 4’-Dimethoxytrityl)-N2-isobutyryl-2’-O-(2-methoxyethyl)guanosine-3’-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite [5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-N6-benzoyladenosin-3'-O-yl]-2-cyanoethyl-N,N-diisopropylphosphoramidite N2-iBu-2'-O-MOE-5'-O-DMT-G-3'-CE-Phosphoramidite N-(9-[(2R,4R,5R)-5-[(bis(4-methoxyphenyl)(phenyl)methoxy)methyl]-4-{[(bis(propan-2-yl)amino)(2-cyanoethoxy)phosphanyl]oxy}-3-(2-methoxyethoxy)oxolan-2-yl]-6-oxo-6,9-dihydro-5H-purin-2-yl)-2-methylpropanamide 2'-O-MOE-rG(ibu)Phosphoramidite DMT-2'-O-MOE-G(iBu)-CEP DMT-2'O-MOE-rG(ib) Phosphoramidite 251647-55-9 C47H60N7O10P RNA Amidites Sigma-Proligo 2-Methyl RNA STD Amidites Amidite