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2'-O-MOE-A(Bz)-3'-phosphoramidite

CAS No.: 251647-53-7

Chemical Name:: 2'-O-MOE-A(Bz)-3'-phosphoramidite

Synonyms: DMT-2'-O-MOE-A(Bz)-CE;2’-MOE-dA(Bz) Amidite;2’-MOE-dA(Bz) Amidite;N6-Bz-5'-O-DMT-2'-O-MOE-A-CE;2'-O-MOE-Bz-A Phosphoramidite;2'-MOE-N-Bz Adenosine Amidite;2'-MOE-Bz-A CE Phosphoramidite;2'-MOE-Bz-A CE Phosphoramidite;2'-O-MOE-rA(Bz)Phosphoramidite;2'-O-MOE-rA(Bz) Phosphoramidite)

CBNumber:: CB83051689

Molecular Formula:: C50H58N7O9P

Molecular Weight:: 932.01

MOL File:: 251647-53-7.mol

Modify Date:: 2024/7/2 8:55:24

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2'-O-MOE-A(Bz)-3'-phosphoramidite Properties

pka	7.87±0.43(Predicted)
form	Solid
color	White to off-white
InChIKey	VPBYBQBHLYRLHG-VCCSSPGHNA-N

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P264-P270-P301+P312-P330-P501

2'-O-MOE-A(Bz)-3'-phosphoramidite Chemical Properties,Uses,Production

Description

2'-O-MOE-A(Bz)-3'-phosphoramidite, also known as DMT-2'-O-MOE-rA(Bz) phosphoramidite, inserts 2'-O-methoxyethyl-modified adenosine into oligonucleotide phosphoramidites for antisense RNA. Its 2'-MOE backbone bolsters duplex stability, nuclease resistance, and has low toxicity, contributing to effective, safe genetic manipulation. It is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).

Chemical Properties

The IUPAC name of 2'-O-MOE-A(Bz)-3'-phosphoramidite is (2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. It is white to off-white powder.

2'-O-MOE-A(Bz)-3'-phosphoramidite Preparation Products And Raw materials

Raw materials

Preparation Products

2'-O-MOE-A(Bz)-3'-phosphoramidite Suppliers

Global( 116)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Innovassynth Technologies (I) Ltd.	+91-2192260100 +91-7208872197	Maharashtra, India	118	58	Inquiry
Gagri Global IT Services Pvt. Ltd.	+91-40-27170174,	Telangana, India	1321	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
Zhejiang Hengkang Pharmaceutical Co., Ltd.	+86-576-83372028 +86-18868723926	China	119	58	Inquiry
Allbiosyn Biotechnology Co.,Ltd.	+8618666985712	China	286	58	Inquiry
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	China	16208	58	Inquiry
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	China	10318	58	Inquiry
BOC Sciences	+1-631-485-4226	United States	19553	58	Inquiry
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	China	30253	58	Inquiry
NewCan Biotech Limited	+86-0571-86912261 +8613735419629	China	9980	58	Inquiry

Supplier	Advantage
Innovassynth Technologies (I) Ltd.	58
Gagri Global IT Services Pvt. Ltd.	58
CLEARSYNTH LABS LTD.	58
Zhejiang Hengkang Pharmaceutical Co., Ltd.	58
Allbiosyn Biotechnology Co.,Ltd.	58
Shanghai Daken Advanced Materials Co.,Ltd	58
Shenzhen Nexconn Pharmatechs Ltd	58
BOC Sciences	58
Career Henan Chemica Co	58
NewCan Biotech Limited	58

251647-53-7(2'-O-MOE-A(Bz)-3'-phosphoramidite)Related Search:

2'-O-Methylcytidine DMT-2μ-O-Me-rG(ib) amidite 2’-O-Methyl-rA(N-Bz)phosphoramidite DMT-2′Fluoro-dU Phosphoramidite 2'-O-(2-Methoxyethyl)-5-methyluridine

N-blocked-5'-O-DMT-2'-O-Me CED cytosine phosphoramidite N4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite Dmt-2'-f-dc(ac) amidite 2'-O-Methyladenosine 2'-O-(2-Methoxyethyl)cytidine

2'-O-Methylguanosine 2'-O-(2-Methoxyethyl)uridine DMT-2'-O-MOE-rU Phosphoramidite 2'-O-MOE-ADENOSINE 2'-OMe-ibu-G Phosphoramidite

2'-O-(2-Methoxyethyl)guanosine

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2'-O-MOE-A(Bz)-3'-phosphoramidite N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)adenosine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] ADENOSINE, N-BENZOYL-5'-O-[BIS(4-METHOXYPHENYL)PHENYLMETHYL]-2'-O-(2-METHOXYETHYL)-, 3'-[2-CYANOETHYL BIS(1-METHYLETHYL)PHOSPHORAMIDITE] (9CI) 2'-O-MOE-Bz-A Phosphoramidite N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-CE phosphoramidite 2'-O-MOE-A(Bz)-CE Phosphoramidite 5'-O-[BIS(4-METHOXYPHENYL)PHENYLMETHYL]-2'-O-ME-A(BZ) PHOSPHORAMIDITE DMT-2'-O-MOE-A(Bz)-CE-Phosphoramidite N6-benzoyl-5'-O-(4, 4'-dimethoxytrityl)-2'-O-methoxyethyl-adenosine-3'-cyanoethyl Phosphoramidite Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] N6-Benzoyl-5’-O-(4,4’-dimethoxy-trityl)-2’-O-(2-methoxyethyl)adeno sine-3’-O-[(2-cyanoethyl)(N,N-diisopropyl)]-phosphorramidite 2'-O-MOE-rA(Bz) Phosphoramidite) 5'-O-DMT-N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine 3'-CE phosphoramidite Adenosine,N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methoxyethyl-N6-benzoyl-adenosine -3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite 5'-DMTr-2'-MOE-N6-Bz-3'-CEP-Adenosine 5'-DMTr-2'-MOE-N6Bz-3'-O-CEP-ADENOSINE DMT-2′O-MOE-rA(bz) Phosphoramidite 2’-O-MOE-A(Bz)-3’-phospho ramidite, N6-Benzoyl-5’-O-(4,4’-dimethoxy-trityl)-2’-O-(2-methoxyethyl)adeno sine-3’-O-[(2-cyanoethyl)(N,N-diisopropyl)]-phosphorramidite N6-Bz-5’-O-DMTr-2’-O-(2-methoxyethyl)-adenosine-3’-CED-phosphoramidite N6-Bz-5'-O-DMT-2'-O-MOE-A-CE 5'-O-DMT-2'-O-MOE-A(Bz)-CE Phosphoramidite 2'-MOE-Bz-A CE Phosphoramidite 5'-O-DMT-2'-O-MOE-N6-Benzoyl- Adenosine -3’-Cyanoethyl Phosphoramidite 2'-MOE-N-Bz Adenosine Amidite DMT-2'-O-MOE-A(Bz)-CE DMTr-2'-O-MOE-rA(Bz)-3'-CE-Phosphoramidite 2’-MOE-dA(Bz) Amidite N6-Benzoyl-2-o-methyladenosine 3-ce phosphoramidite N6-Benzoyl-5’-O-(4, 4’-dimethoxytrityl)-2’-O-(2-methoxyethyl)adenosine-3’-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite 5'-ODMT-2'-OMOE-N-Bz Adenosine-3'-OCEPA 2'-O-MOE-A(Bz)-3'-phosphoramidite DMT-2'-O-MOE-A(Bz)-CE Phosphoramidite 2'-MOE-Bz-A CE Phosphoramidite 2'-O-MOE-A(Bz)-CE-Phosphoramidite 2’-MOE-dA(Bz) Amidite N6-benzoyl-5'-O-(4, 4'-dimethoxytrityl)-2'-O-methoxyethyl-adenosine-3'-cyanoethyl Phosphoramidite (2R,3R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite N6-Bz-2'-O-MOE-5'-O-DMT-A-3'-CE-Phosphoramidite 2'-O-MOE-rA(Bz)Phosphoramidite 5'-O-[BIS(4-METHOXYPHENYL)PHENYLMETHYL]-2'-O-ME-A(BZ) PHOSPHORAMIDITE DMT-2'-O-MOE-rA(Bz) phosphoramidite 251647-53-7 C50H58N7O9P Amidite