ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Pyrimidines >Urine (urea) pyrimidine >6-Azauracil
6-Azauracil
- CAS No.
- 461-89-2
- Chemical Name:
- 6-Azauracil
- Synonyms
- 1,2,4-TRIAZINE-3,5(2H,4H)-DIONE;1,2,4-triazine-3,5-diol;Azauracil;AZU;6-AU;nsc3425;ipo3834;IPO 3834;NSC 3425;USAF cb-30
- CBNumber:
- CB9223189
- Molecular Formula:
- C3H3N3O2
- Molecular Weight:
- 113.07
- MOL File:
- 461-89-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/5/10 18:56:37
| Melting point | 274-275 °C(lit.) |
|---|---|
| Boiling point | 211.75°C (rough estimate) |
| Density | 1.5988 (rough estimate) |
| refractive index | 1.4264 (estimate) |
| storage temp. | Store below +30°C. |
| form | Fine Crystalline Powder |
| pka | 7.78±0.20(Predicted) |
| color | White to light yellow |
| Water Solubility | Partly soluble in water, ethanol, DMSO, and 1 M NH4OH (50 mg/ml). |
| BRN | 116472 |
| InChI | InChI=1S/C3H3N3O2/c7-2-1-4-6-3(8)5-2/h1H,(H2,5,6,7,8) |
| InChIKey | SSPYSWLZOPCOLO-UHFFFAOYSA-N |
| SMILES | N1=CC(=O)NC(=O)N1 |
| CAS DataBase Reference | 461-89-2(CAS DataBase Reference) |
| NIST Chemistry Reference | 1,2,4-Triazine-3,5(2H,4H)-dione(461-89-2) |
| EPA Substance Registry System | 1,2,4-Triazine-3,5(2H,4H)-dione (461-89-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H301-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P301+P310a-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi,T | |||||||||
| Risk Statements | 36/37/38-63-25 | |||||||||
| Safety Statements | 26-36-45-38-36/37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | XY7700000 | |||||||||
| F | 10-23 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29336980 | |||||||||
| NFPA 704 |
|
6-Azauracil price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | A1757 | 6-Azauracil ≥98% | 461-89-2 | 5G | ₹4589.8 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.41156 | 6-Azauracil for synthesis | 461-89-2 | 5G | ₹7040 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.41156 | 6-Azauracil for synthesis | 461-89-2 | 25G | ₹47110 | 2022-06-14 | Buy |
| TCI Chemicals (India) | A0558 | 6-Azauracil | 461-89-2 | 1G | ₹1800 | 2022-05-26 | Buy |
| TCI Chemicals (India) | A0558 | 6-Azauracil | 461-89-2 | 5G | ₹4300 | 2022-05-26 | Buy |
6-Azauracil Chemical Properties,Uses,Production
Chemical Properties
white to light yellow fine crystalline powder
Uses
6-Azauracil (6-AU) is used as a growth inhibitor of various microorganisms via depletion of intracellular GTP and UTP nucleotide pools. 6-Azauracil has been widely used in investigations on modulation of transcription, especially in yeast models.
Definition
ChEBI: 6-azauracil is a 1,2,4-triazine compound having oxo-substituents at the 3- and 5-positions. It has a role as an antimetabolite. It is a member of 1,2,4-triazines and a nucleobase analogue.
Safety Profile
Poison by intraperitoneal route. Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Mode of action
6-Azauracil is a growth inhibitor effective on a variety of microorganisms. It functions by depleting the intracellular GTP and UTP nucleotide supply. Mutations in transcriptional elongation machinery, as well as mutations in a variety of other pathways, exaggerate the growth defect of cells in the presence of 6 AU.
6-Azauracil Preparation Products And Raw materials
Global( 281)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| Reax Chemicals | 08048372701Ext 416 | Hyderabad, India | 4223 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Unipharm pharmaceutical industry Co., Ltd | 536-8266195 +8613953676784 | China | 1206 | 58 | Inquiry |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29888 | 58 | Inquiry |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | China | 2136 | 58 | Inquiry |
| Accela ChemBio Inc. | +1-858-6993322 | United States | 19479 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49392 | 58 | Inquiry |
461-89-2(6-Azauracil)Related Search:
Buprofezin
5-BROMO-6-AZAURACIL ,97%,5-BROMO-6-AZAURACIL
6-AZAURACIL RIBOSIDE,6-azauracil-beta-d-ribosid
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AZAURACIL, 5-(RG)
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4(6)-Azauracil
As-Triazine-3,5(2H,4H)-dione
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ipo3834
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nsc3425
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AZAURACIL, 6-
6-AZA-2,4-DIHYDROXYPYRIMIDINE
6-AZAURACIL
3,5-DIHYDROXY-1,2,4-TRIAZINE
2H,4H-AS-TRIAZINE-3,5-DIONE
1,2,4-TRIAZINE-3,5-DIONE
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6-AZAURACIL 99%
6-Azauracil,98%
6-AZAURAZIL
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S-TRIAZINE-3,5-DIONE
3,5-DIOXO-[1,2,4]TRIAZINE
1,2,4-Triazine-3,5(2H,4H)
1,2,4-Triazine-3,5(2H,4H)-dione, 3,5-Dihydroxy-1,2,4-triazine, 6-Aza-2,4-dihydroxypyrimidine
2,3,4,5-Tetrahydro-1,2,4-triazine-3,5-dione
6-Azauracil,99%
2H-1,2,4-triazine-3,5-dione
2H-1,2,4-triazine-3,5-quinone
as-Triazine-3,5(2H,4H)-dione (8CI)
WLN: T6NMVMVJ
6 - nitrogen iMpurity uracil
6-azauridine 6-Azauracil
6-Azauracil >
Azauracil
AZU
1,2,4-triazine-3,5-diol
1,2,4-TRIAZINE-3,5(2H,4H)-DIONE
6-AU
1,2,4-Triazine-3,5(2H,4H)-dione (9CI, ACI)
461-89-2
BioChemical
Biochemicals and Reagents
Nucleosides, Nucleotides, Oligonucleotides
Nucleoside Analogs
Biochemistry
Nucleobases and their analogs
Nucleosides, Nucleotides & Related Reagents
Nucleic acids
Pyridines, Pyrimidines, Purines and Pteredines