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ChemicalBook > Product Catalog >API >Blood System Drugs >Anticoagulant and Antiplatelet Drugs >Dabigatran Etexilate Mesylate

Dabigatran Etexilate Mesylate

Dabigatran Etexilate Mesylate Structure
CAS No.
872728-81-9
Chemical Name:
Dabigatran Etexilate Mesylate
Synonyms
Pradaxa;Pradaxa Mesylate;Dabigatran mesylate;Dabigatran Etexilate Mesylate API;Ethyl 3-(2-(((4-(N-((hexyloxy)carbonyl)carbamimidoyl)phenyl)amino)methyl)-1-methyl-N-(pyridin-;Hexyl 2-(4-(((5-((3-ethoxy-3-oxopropyl)(pyridin-2-yl)carbaMoyl)-1-Methyl-1H-benzo[d]iMidazol-2-yl)Methyl)aMino)benzylidene)hydrazinecarboxylate Methanesulfonate;(E)-hexyl 2-(4-((5-((3-ethoxy-3-oxopropyl)(pyridin-2-yl)carbaMoyl)-1-Methyl-1H-benzo[d]iMidazol-2-yl)MethylaMino)benzylidene)hydrazinecarboxylate Methanesulfonate;ethyl 3-(2-(((4-(N-((hexyloxy)carbonyl)carbamimidoyl)phenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate methanesulfonate;N-[[2-[[[4-[[[(Hexyloxy)carbonyl]amino]iminomethyl]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-beta-alanine ethyl ester monomethanesulfonat;Dabig
CBNumber:
CB92500679
Molecular Formula:
C35H45N7O8S
Molecular Weight:
723.85
MOL File:
872728-81-9.mol
MSDS File:
SDS
Modify Date:
2024/6/4 19:18:49
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Dabigatran Etexilate Mesylate Properties

Melting point >125°C
storage temp. Refrigerator
solubility DMSO (Slightly, Heated), Methanol (Slightly)
form Solid
color White to Pale Yellow

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07,GHS08
Signal word  Danger
Hazard statements  H413
NFPA 704
0
2 0

Dabigatran Etexilate Mesylate Chemical Properties,Uses,Production

Chemical Properties

Off-White to Pale Yellow Solid

Uses

Nonpeptide, direct thrombin inhibitor. Antithrombotic.

Clinical Use

Dabigatran Etexilate Mesylate is a direct thrombin inhibitor indicated to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation.

Definition

ChEBI: A methanesulfonate salt obtained by reaction of dabigatran etexilate with one equivalent of dabigatran etexilate. A prodrug for dabigatran, a thrombin inhibitor and anticoagulant which is used for the prevention of stroke and systemic embolism.

Side effects

The most common adverse reactions to Dabigatran Etexilate Mesylate (150 mg) were bleeding and gastrointestinal events (i.e. dyspepsia, nausea, epigastric pain, gastrointestinal bleeding, and diarrhoea). Very few patients experienced drug hypersensitivity (including urticaria, rash and pruritus), anaphylactic oedema, anaphylactic reactions and anaphylaxis.

Dabigatran Etexilate Mesylate Preparation Products And Raw materials

Raw materials

Dabigatran etexilate Methanesulfonic acid

Preparation Products

Dabigatran Etexilate Mesylate Suppliers

Global( 455)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
SGMR PHARMACEUTICALS PVT LTD +91-9032001889 +91-9032001889 Telangana, India 83 58 Inquiry
ALMELO PRIVATE LIMITED +91-9100991345 +91-8500807769 Telangana, India 114 58 Inquiry
Dr. Reddy's Laboratories Ltd +91-4049002900 +91-4049002900 Hyderabad, India 165 58 Inquiry
SEUTIC +91-8309787199 +91-8309787199 Hyderabad, India 124 58 Inquiry
Metrochem API Private Limited +91-4069069999 +91-4069069999 Telangana, India 78 58 Inquiry
SVK Laboratories Pvt Ltd +91-40-23095079 +91-9177729915 Telangana, India 89 58 Inquiry
Synaptics Labs Private Limited +91-8341963666 +91-8341963666 Hyderabad, India 84 58 Inquiry
Sekhment pharmaventures +91-9030088669 +91-9030088669 Mumbai, India 105 58 Inquiry
Apotex Pharmachem India Pvt Ltd +91-8022891034 +91-8022891000 Karnataka, India 109 58 Inquiry
Lupin Ltd +91-8019896181 +91-8019896181 Maharashtra, India 93 58 Inquiry
Supplier Advantage
SGMR PHARMACEUTICALS PVT LTD 58
ALMELO PRIVATE LIMITED 58
Dr. Reddy's Laboratories Ltd 58
SEUTIC 58
Metrochem API Private Limited 58
SVK Laboratories Pvt Ltd 58
Synaptics Labs Private Limited 58
Sekhment pharmaventures 58
Apotex Pharmachem India Pvt Ltd 58
Lupin Ltd 58

Dabigatran Etexilate Mesylate Spectrum

Dabigatran Etexilate Mesylate(872728-81-9)1HNMR

872728-81-9(Dabigatran Etexilate Mesylate)Related Search:

5-(2-Bromoethyl)-2,3-dihydrobenzofuran 3-(S)-(+)-(1-Carbamoyl-1,1-diphenylmethyl)pyrroloidine-L-(+)-tartarate Dabigatran Etexilate iMpurity 4 Dabigatran Etexilate iMpurity 3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester
N-(4-CYANO-PHENYL)-GLYCINE Chloroacetic anhydride 4-Aminobenzamidine dihydrochloride 3-[(3-AMINO-4-METHYLAMINO-BENZOYL)-PYRIDIN-2-YL-AMINO]-PROPIONIC ACID ETHYL ESTER HEXYL CHLOROFORMATE
N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-(2-pyridinyl)-beta-alanine ethyl ester hydrochloride Dabigatran Etexilate iMpurity D Dabigatran iMpurity E Des-(N-2-pyridyl-β-alanine Ethyl Ester) Dabigatran Etexilate 5-Ethyl Carboxylate (Dabigatran IMpurity) Dabigatran iMpurity F
Dabigatran etexilate Dabigatran
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Dabigatran etexilate mesylate (Z)-ethyl 3-(2-(((4-(N'-((hexyloxy)carbonyl)carbamimidoyl)phenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate methanesulfonate Dabigatran etexilate mesylate,Pradaxa Dabigatran etexilate Mesylate 872728-81-9 [[[(Hexyloxy)carbonyl]aMino]iMinoMethyl]phenyl]aMino]Methyl]-1-Methyl-1H-benziMidazol-5-yl]carbonyl]-N-2-pyridinyl-beta-alanineethylesterMonoMethanesulfonat N-[[2-[[[4-[[[(Hexyloxy)carbonyl]aMino]iMinoMethyl]phenyl]aMino]Methyl]-1-Methyl-1H-benziMidazol-5-y BIBR 1048MS N-[[2-[[[4-[[[(Hexyloxy)carbonyl]aMino]iMinoMethyl]phenyl]aMino]Methyl]-1-Methyl-1H-benziMidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine Ethyl Ester Methanesulfonate Dabigatran etexilate Methanesulfonate PRADAXA; BIBR 1048MS; DABIGATRAN ETEXILATE METHANESULFONATE ate MesyL atran EtexiL Dabig Dabigatran EtexiL Dabigatran Etexilate Mesylate USP/EP/BP Dabigatran Etexilate Mesylate Pellet Dabigatran Etexilate Mesylate- IH B-Alanine, N-[[2-[[[4-[[[(hexyloxy) carbonyl] amino] iminomethyl] phenyl] amino] methyl]-1-methyl-1H-benzimidazol-5-yl] carbonyl]-N-2-pyridinyl -,ethyl ester, methanesulfonate N-[[2-[[[4-[[[(Hexyloxy)carbonyl] amino]iminomethyl]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine ethyl ester methanesulfonate Dabigatran Etexilate MesylateQ: What is Dabigatran Etexilate Mesylate Q: What is the CAS Number of Dabigatran Etexilate Mesylate Q: What is the storage condition of Dabigatran Etexilate Mesylate Q: What are the applications of Dabigatran Etexilate Mesylate Dabigatran Mesylate Reference N-[[2-[[[4-[[[(Hexyloxy)carbonyl]amino]iminomethyl]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-beta-alanine ethyl ester monomethanesulfonat supplier in Chin CS-900 3-([2-[[(4-(N-n-hexyloxycarbonylcarbamimidoyl)-phenylamino)-methyl]]-1-methyl-1H-benzimidazole-5-carbonyl]-pyridin-2-yl-amino)ethyl propionate mesylate Ethyl 3-(2-(((4-(N-((hexyloxy)carbonyl)carbamimidoyl)phenyl)amino)methyl)-1-methyl-N-(pyridin- N-[[2-[[[4-[[[(Hexyloxy)carbonyl]amino]iminomethyl]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-beta-alanine ethyl ester monomethanesulfonat Pradaxa Hexyl 2-(4-(((5-((3-ethoxy-3-oxopropyl)(pyridin-2-yl)carbaMoyl)-1-Methyl-1H-benzo[d]iMidazol-2-yl)Methyl)aMino)benzylidene)hydrazinecarboxylate Methanesulfonate (E)-hexyl 2-(4-((5-((3-ethoxy-3-oxopropyl)(pyridin-2-yl)carbaMoyl)-1-Methyl-1H-benzo[d]iMidazol-2-yl)MethylaMino)benzylidene)hydrazinecarboxylate Methanesulfonate Pradaxa Mesylate Dabigatran Etexilate Mesylate API ethyl 3-(2-(((4-(N-((hexyloxy)carbonyl)carbamimidoyl)phenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate methanesulfonate Dabigatran mesylate Dabigatran etexilatemesi Pradaxa, Dabigatran etexilate mesylate 872728-81-9 C34H41N7O5CH4O3S C35H45N7O8S Aromatics Bases & Related Reagents Heterocycles Intermediates & Fine Chemicals Nucleotides Pharmaceuticals Dabigatran etexilate mesylate API 872728-81-9