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Carbonic Anhydrase IX/XII Inhibitor II(U-104)

Carbonic Anhydrase IX/XII Inhibitor II(U-104) Structure
CAS No.
178606-66-1
Chemical Name:
Carbonic Anhydrase IX/XII Inhibitor II(U-104)
Synonyms
U-104;DNAJA4;MSTP104;PRO1472;CS-1653;MST-104 ;SLC-0111;NSC 213841;U-104, >98%;U104(SLC-0111)
CBNumber:
CB92630071
Molecular Formula:
C13H12FN3O3S
Molecular Weight:
309.32
MOL File:
178606-66-1.mol
MSDS File:
SDS
Modify Date:
2023/6/8 9:02:17

Carbonic Anhydrase IX/XII Inhibitor II(U-104) Properties

Melting point 242-243℃
Density 1.523±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. 2-8°C
solubility DMSO: >15mg/mL
form powder
pka 9.94±0.12(Predicted)
color white to beige

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H320-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36
Safety Statements  26
WGK Germany  3
NFPA 704
0
2 0

Carbonic Anhydrase IX/XII Inhibitor II(U-104) price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SML0374 U-104 ≥98% (HPLC) 178606-66-1 5MG ₹10846.65 2022-06-14 Buy
Sigma-Aldrich(India) SML0374 U-104 ≥98% (HPLC) 178606-66-1 25MG ₹43830.43 2022-06-14 Buy
Product number Packaging Price Buy
SML0374 5MG ₹10846.65 Buy
SML0374 25MG ₹43830.43 Buy

Carbonic Anhydrase IX/XII Inhibitor II(U-104) Chemical Properties,Uses,Production

Uses

U 104 targets hypoxia-induced carbonic anhydrase IX, which inhibits tumor growth and metastasis.

Biochem/physiol Actions

U-104 is an inhibitor of CA IX that binds only to CA IX under hypoxic conditions in vivo. The binding results in significant inhibition of tumor growth and metastasis formation in both spontaneous and experimental models of metastasis. U-104 reduces the medium acidity by inhibiting the catalytic activity of the CA IX. It binds specifically only to hypoxic cells expressing CA IX.

Carbonic Anhydrase IX/XII Inhibitor II(U-104) Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 130)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29897 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
SHANGHAI T&W PHARMACEUTICAL CO., LTD. +86-021-61551413 +8618813727289 China 5738 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 24607 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Coresyn Pharmatech Co., Ltd. +86-571-86626709 +86-18157142896 China 9991 58 Inquiry

Carbonic Anhydrase IX/XII Inhibitor II(U-104) Spectrum

NSC 213841 Carbonic Anhydrase IX/XII Inhibitor II(U-104) U-104 MST-104 4-[[[(4-Fluorophenyl)amino]carbonyl]amino]benzenesulfonamide U104/NSC 213841/MST104 U-104;NSC 213841;U 104 4-[[[(4-Fluorophenyl)aMino]carbonyl]aMino]-benzenesulfonaMide, NSC 213841 Benzenesulfonamide, 4-[[[(4-fluorophenyl)amino]carbonyl]amino]- 4-(3-(4-fluorophenyl)ureido)benzenesulfonamide Anti-DNAJA4 antibody produced in rabbit DNAJA4 MSTP104 PRO1472 CS-1653 arbonic Anhydrase IX/XII Inhibitor II(U-104) NSC-213841; MST-104;U104;U 104 4-[[[(4-Fluorophenyl)amino]carbonyl]amino]-benzesulfonamide 4-{[(4'-fluorophenyl)carbamoyl]amino}benzenesulfonamide U-104, >98% U-104 (NSC-213841) SLC-0111 U-104 >=98% (HPLC) 1-(4-Fluorophenyl)-3-(4-sulfamoylphenyl)urea Carbonic Anhydrase IX/XII Inhibitor II(U-104) USP/EP/BP U104(SLC-0111) LM2-4,U 104,CAIX,CAI,CAXII,U104,U-104,exosome,SLC-0111,SLC0111,Carbonate dehydratase,Carbonic Anhydrase,inhibit,SLC 0111,4T1,Inhibitor,CAII 4-{[(4'-fluorophenyl)carbamoyl]amino}benzenesulfonamide 178606-66-1 Inhibitors Inhibitor