2,3-Naphthalenedicarboxylic Anhydride
- CAS No.
- 716-39-2
- Chemical Name:
- 2,3-Naphthalenedicarboxylic Anhydride
- Synonyms
- EA253;2,3-NAPHTHALI;2,3-NAPHTHALIC ANHYDRIDE;naphtho[2,3-c]furan-1,3-dione;benzo[f][2]benzofuran-1,3-dione;benzo[f]isobenzofuran-1,3-quinone;2,3-Napthalenedicarboxycanhydride;2,3-NAPHTHALENEDICARBOXYLIC ANHYDRIDE;2,3-NaphthalenedicarboxylicAnhydride>1,3-Dihydronaphtho[2,3-c]furan-1,3-dione
- CBNumber:
- CB9286597
- Molecular Formula:
- C12H6O3
- Molecular Weight:
- 198.17
- MOL File:
- 716-39-2.mol
- Modify Date:
- 2023/8/31 10:02:46
| Melting point | 246 °C |
|---|---|
| Boiling point | 275-280 °C(Press: 100 Torr) |
| Density | 1.449±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| form | Solid |
| color | Pale Beige |
| Stability | Moisture Sensitive |
| InChI | InChI=1S/C12H6O3/c13-11-9-5-7-3-1-2-4-8(7)6-10(9)12(14)15-11/h1-6H |
| InChIKey | IZJDCINIYIMFGX-UHFFFAOYSA-N |
| SMILES | O1C(=O)C2=CC3C(C=C2C1=O)=CC=CC=3 |
| EPA Substance Registry System | Naphtho[2,3-c]furan-1,3-dione (716-39-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| Safety Statements | 22-24/25 |
| HS Code | 2917.39.7000 |
2,3-Naphthalenedicarboxylic Anhydride price More Price(2)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemicals (India) | N0530 | 2,3-Naphthalenedicarboxylic Anhydride min. 95.0 % | 716-39-2 | 25G | ₹8600 | 2022-05-26 | Buy |
| TCI Chemicals (India) | N0530 | 2,3-Naphthalenedicarboxylic Anhydride min. 95.0 % | 716-39-2 | 250G | ₹13200 | 2022-05-26 | Buy |
2,3-Naphthalenedicarboxylic Anhydride Chemical Properties,Uses,Production
Description
A few years ago, the product was still synthesized from the corresponding diacid, but in recent years, it has been difficult to find the shadow of the diacid in the market, and the sales of this product have been repeatedly restricted, resulting in high prices.
Uses
2,3-Naphthalic anhydride is used as a reagent to synthesize analogues of Thalidomide (T338850), an inhibitor of tumour necrosis factor that was once abandoned because it caused birth defects, but is currently used as an inhibitor of angiogenesis in patients with multiple myeloma.
Preparation
Add anhydrous tetrahydrofuran (its mass ratio to maleic anhydride is 1.5:1), cat-1 (0.05 mole), maleic anhydride (1 mole), and o-phthalaldehyde (1.5 mole) to the reactor. After adding triethylamine (5 moles), adjust the temperature below -40°C. Silicon tetrachloride (4 moles) was added dropwise to the reaction system and the reaction was placed at -40 °C for 4 h. The mixture was heated to reflux for 20 h. After the end of the reaction, concentrating the solution to a certain concentration with diatomaceous earth filtration. A light yellow solid, namely 2,3-Naphthalenedicarboxylic Anhydride, is obtained by precipitation, filtration, recrystallization and drying. Its yield reaches 88%.
2,3-Naphthalenedicarboxylic Anhydride Preparation Products And Raw materials
Raw materials
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| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| VGS SYNTHESIS PRIVATE LIMITED | +91-9866975588 +91-9866975588 | Hyderabad, India | 1818 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Changzhou uniringchem Co., Ltd. | +undefined13585446801 | China | 68 | 58 | Inquiry |
| Sirichem (Zhangjiakou) Sci-Tech.Co.,Ltd. | +8615831567206 | China | 58 | 58 | Inquiry |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | China | 16209 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21669 | 55 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29898 | 58 | Inquiry |
716-39-2(2,3-Naphthalenedicarboxylic Anhydride)Related Search:
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