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N-[4-Cyano-3-(trifluoromethyl)phenyl]methacrylamide epoxide

N-[4-Cyano-3-(trifluoromethyl)phenyl]methacrylamide epoxide Structure
CAS No.
90357-51-0
Chemical Name:
N-[4-Cyano-3-(trifluoromethyl)phenyl]methacrylamide epoxide
Synonyms
N-[4-Cyano-3-(triflu;Bicalutamide Impurity 16;Bicalutamide Epoxide Impurity;Bicalutamide Oxirane Impurity;Bicalutamide intermediate (epoxy);N-[4-Cyano-3-(trifluoroMethyl)phenyl]MethacrylaMid;1,2-EPOXY-2-METHYL-N-[4-CYANO-3-(TRIFLUOROMETHYL)];N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane;Bicalutamide Impurity 3 (Bicalutamide Epoxide Impurity);N-[4-Cyano-3-(Trifluoromethyl)Phenyl]-2-Methyl-2-Oxirane
CBNumber:
CB9338843
Molecular Formula:
C12H9F3N2O2
Molecular Weight:
270.21
MOL File:
90357-51-0.mol
MSDS File:
SDS
Modify Date:
2023/6/8 17:06:38

N-[4-Cyano-3-(trifluoromethyl)phenyl]methacrylamide epoxide Properties

Melting point 151-152 °C
Boiling point 436.4±45.0 °C(Predicted)
Density 1.42±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka 12.08±0.70(Predicted)
color White to Off-White
CAS DataBase Reference 90357-51-0(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319
Precautionary statements  P501-P261-P270-P271-P264-P280-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330-P302+P352+P312-P304+P340+P312
Safety Statements  24/25
HS Code  29269090
NFPA 704
0
2 0

N-[4-Cyano-3-(trifluoromethyl)phenyl]methacrylamide epoxide price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemicals (India) C3607 N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide min. 95.0 % 90357-51-0 5G ₹2800 2022-05-26 Buy
TCI Chemicals (India) C3607 N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide min. 95.0 % 90357-51-0 25G ₹8000 2022-05-26 Buy
Product number Packaging Price Buy
C3607 5G ₹2800 Buy
C3607 25G ₹8000 Buy

N-[4-Cyano-3-(trifluoromethyl)phenyl]methacrylamide epoxide Chemical Properties,Uses,Production

Uses

N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide, is an intermediate in synthesis of more complex pharmaceutical compounds. It is used in the synthesis of potential impurities of Bicalutamide (B382000), which is an oral nonsteroidal, anti-androgen drug used for prostate cancer.

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N-[4-CYANO-3-(TRIFLUOROMETHYL)PHENYL]METHACRYLAMIDE EPOXIDE (INTERMEDIATE OF BICALUTAMIDE) 4’-Cyano-3’-trifluoromethyl-2,3-epoxy-2-methylpropioanilide N-[4-Cyano-3-(Trifluoromethyl)Phenyl]-2-Methyloxiranecarboxamide ( For Bicalutamide ) N-[4-Cyano-3-(trifluoroMethyl)phenyl]MethacrylaMid N-[4-Cyano-3-(triflu n-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide N-4-CYANO-3-(TRIFLUOROMETHYL)PHENYLMETHACRYLAMIDE EPOXIDE 1,2-EPOXY-2-METHYL-N-[4-CYANO-3-(TRIFLUOROMETHYL)] 1,2-Epoxy-2-methyl-N[4-cyano-3(trifluoromethyl)-phenyl] propanamide (Intermediate for Bicalutamide) 1,2-Epoxy-2-Methyl-N[4-Cyano-3(Trifluoromethyl)-Phenyl]Propanamide N-[4-CYANO-3-(TRIFLUOROMETHYL)PHENYL]-2-METHYL-2-OXIRANE CARBOXAMIDE N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-Oxiranecarboxamide N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyl-oxiranecarboxamine 1,2-Epoxy-2-methyl-N-(4-cyano-3-trifluoromethyl)-phenyl)propaneamide N-[4- Cyano-3-trifluoroMethy phenyl]-2-oxirane carboxaMide Bicalutamide Epoxide Impurity 2-Methyl-oxirane-2-carboxylic acid (4- cyano-3- trifluoromethylphenyl)-amide Bicalutamide Oxirane Impurity N-[4-Cyano-3-(trifluoromethyl)phenyl]-methacrylamide exoxide N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-oxiranecarboxamide Bicalutamide Impurity 16 Bicalutamide Impurity 3 (Bicalutamide Epoxide Impurity) N-[4-Cyano-3-(Trifluoromethyl)Phenyl]-2-Methyl-2-Oxirane 2-Oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl- Oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl- N-[4-Cyano-3-(Trifluoromethyl)Phenyl]-2-Methyl-2-Oxirane Car... Bicalutamide Impurity 14 (Bicalutamide Epoxide Impurity) Bicalutamide intermediate (epoxy) N-[4-Cyano-3-(trifluoromethyl)phenyl]methacrylamide epoxide N - [4-Cyano-3- (trifluoromethyl) phenyl] methylepoxy acrylamide N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane Bicalutamide intermediate (epoxy) 90357-51-0 Bicalutamide API intermediates Chemical intermediate for Bicalutamide