5-Chlorovaleryl chloride
- CAS No.
- 1575-61-7
- Chemical Name:
- 5-Chlorovaleryl chloride
- Synonyms
- 5-CHLOROPENTANOYL CHLORIDE;5-Chlorvalerylchlorid;5-CHLOROVALEROYL CHLORIDE;orovaL;5-Chlorovaleryl;Apixaban Impurity 56;5-chloro aMyl chloride;5 - chlorine e chloride;5-chloro-valerylchlorid;5-chlorvaleryl chloride
- CBNumber:
- CB9348033
- Molecular Formula:
- C5H8Cl2O
- Molecular Weight:
- 155.02
- MOL File:
- 1575-61-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/1/18 17:03:10
| Boiling point | 38-39 °C0.15 mm Hg(lit.) |
|---|---|
| Density | 1.206 g/mL at 20 °C |
| refractive index |
n |
| Flash point | 195 °F |
| storage temp. | Store below +30°C. |
| solubility | Acetonitrile (Slightly), Chloroform (Sparingly) |
| form | Liquid |
| color | Clear colorless to slightly yellow |
| Specific Gravity | 1.200 |
| PH | <7 (H2O, 20℃) |
| explosive limit | 2.0-10.2%(V) |
| Water Solubility | reacts |
| Sensitive | Moisture Sensitive |
| BRN | 1745182 |
| Stability | Corrosive, Moisture Sensitive |
| InChIKey | SVNNWKWHLOJLOK-UHFFFAOYSA-N |
| CAS DataBase Reference | 1575-61-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H314 | |||||||||
| Precautionary statements | P270-P280-P301+P312-P303+P361+P353-P304+P340+P310-P305+P351+P338 | |||||||||
| Hazard Codes | C,T | |||||||||
| Risk Statements | 22-34-23-23/34 | |||||||||
| Safety Statements | 26-36/37/39-45 | |||||||||
| RIDADR | UN 3265 8/PG 2 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | YV9108000 | |||||||||
| F | 10-19-21 | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29159000 | |||||||||
| NFPA 704 |
|
5-Chlorovaleryl chloride price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 125245 | 5-Chlorovaleroyl chloride 96% | 1575-61-7 | 10G | ₹15826.15 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 125245 | 5-Chlorovaleroyl chloride 96% | 1575-61-7 | 50G | ₹29054.3 | 2022-06-14 | Buy |
| TCI Chemicals (India) | C1789 | 5-Chlorovaleryl Chloride min. 98.0 % | 1575-61-7 | 5G | ₹3300 | 2022-05-26 | Buy |
| TCI Chemicals (India) | C1789 | 5-Chlorovaleryl Chloride min. 98.0 % | 1575-61-7 | 25G | ₹8700 | 2022-05-26 | Buy |
| ALFA India | ALF-H56237-22 | 5-Chlorovaleroyl chloride, 98% | 1575-61-7 | 100g | ₹34512 | 2022-05-26 | Buy |
5-Chlorovaleryl chloride Chemical Properties,Uses,Production
Chemical Properties
clear colourless to slightly yellow liquid
Uses
5-Chlorovaleroyl chloride (5-CVC) has been used in the development and validation of a GC-FID method for the analysis of low level impurities present in 5-CVC. It has been used in the synthesis of anion-exchange resins by acylation of polystyrene/divinylbenzene and subsequent amination with trimethylamine. It is commonly used as alkylating agent in the synthesis of pharmaceutical intermediates and other specialty chemicals.
Application
5-Chlorovaleryl chloride is an important medicine and pesticide intermediate. It is pharmaceutically mainly for the manufacture of the medicine Cilostazole (Cilostazol) for anti-platelet aggregation, protection of vascular endothelial cells, and atherosclerosis.5-Chlorovaleryl Chloride is also for the production of paddy rice New-type wide-spectrum weedicide pyraclonil (Pyraclonil).
General Description
5-Chlorovaleroyl chloride is commonly used as alkylating agent in the synthesis of pharmaceutical intermediates and other specialty chemicals.
Synthesis
In the existing process, producing 5-Chlorovaleryl chloride using 1,4-dichlorobutane as raw material requires a three-step reaction. First, 1,4-dichlorobutane and sodium cyanide solution are combined to form 5-chlorovaleronitrile. Then, the prepared 5-chlorovaleronitrile is hydrolyzed in concentrated hydrochloric acid to form 5-chlorovaleric acid. Finally, 5-chlorovaleronitrile reacts with thionyl chloride to generate 5-chlorovaleryl chloride.
5-Chlorovaleryl chloride Preparation Products And Raw materials
Raw materials
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| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Dynarx Technology India Limited | +91-9960099480 +91-9960099480 | Bangalore, India | 71 | 58 | Inquiry |
| Anant Pharmaceuticals Pvt Ltd | +91-8550986868 +91-9485998001 | Haryana, India | 461 | 58 | Inquiry |
| SRIGEN LIFE SCIENCES PVT LTD | +919866542802 | Hyderabad, India | 60 | 58 | Inquiry |
| Svak Life Sciences | +91-9963463333 +91-9705383777 | Hyderabad, India | 101 | 58 | Inquiry |
| Paushak Limited | +91-2653007932 +91-9727736899 | Vadodara, India | 59 | 58 | Inquiry |
| Aether Industries Limited | +91-261-6603130 +91-2616603130 | Gujarat, India | 145 | 58 | Inquiry |
| Briti Scientific | +91-8790384772 +91-8179784772 | Telangana, India | 54 | 58 | Inquiry |
| Orgamine Chemicals(I) Pvt Ltd | +91-9820080281 +91-9820080281 | Maharashtra, India | 451 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
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