Diphenylpyraline Hydrochloride
- CAS No.
- 132-18-3
- Chemical Name:
- Diphenylpyraline Hydrochloride
- Synonyms
- Lergobine;Hy-stamin;DIPHENYLPYRALINE HCL;LABOTEST-BB LT00159897;Diphenylpyraline hydrochlorid;DIPHENYLPYRALINE HYDROCHLORIDE;4-diphenylmethoxy-1-methylpiperidine;4-(benzhydryloxy)-1-methylpiperidine;4-(Diphenyl Methoxy)-1-piperidine HCl;4-BENZHYDRYLOXY-1-METHYL PIPERIDINE HCL
- CBNumber:
- CB9356441
- Molecular Formula:
- C19H24ClNO
- Molecular Weight:
- 317.85
- MOL File:
- 132-18-3.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/5/18 11:31:12
| Melting point | 203-205 °C(lit.) |
|---|---|
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| form | Solid |
| color | White to Off-White |
| Merck | 13,3363 |
| Stability | Hygroscopic |
| EPA Substance Registry System | Diphenylpyraline hydrochloride (132-18-3) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
| Hazard Codes | Xn |
| Risk Statements | 20/21/22-36/37/38-22 |
| Safety Statements | 26-36 |
| RIDADR | 3249 |
| WGK Germany | 3 |
| RTECS | TM7823600 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| Toxicity | mouse,LD50,intramuscular,64300ug/kg (64.3mg/kg),Drugs in Japan Vol. 6, Pg. 333, 1982. |
Diphenylpyraline Hydrochloride price More Price(2)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 280550 | 4-Diphenylmethoxy-1-methylpiperidine hydrochloride 95% | 132-18-3 | 10G | ₹6137.78 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 280550 | 4-Diphenylmethoxy-1-methylpiperidine hydrochloride 95% | 132-18-3 | 10G | ₹6137.78 | 2022-06-14 | Buy |
Diphenylpyraline Hydrochloride Chemical Properties,Uses,Production
Description
Diphenylpyraline is an antihistamine drug with anticholinergic and sedative action. It is intended for symptomatic treatment of seasonal allergies and allergic reactions as well as an adjuvant drug in anaphylactic reaction therapy. Synonyms of this drug are arbid, timpil, histryl, hispril, and others.
Uses
Diphenylpyraline Hydrochloride is a salt of Diphenylpyraline (D492110), an H1 receptor antagonist (an antihistamine) and is commonly prescribed to treat allergic and vasomotor rhinitis. There is also some research being conducted on diphenylpyraline derivatives to determine their antimycobacterial and antifungal activity.
Definition
ChEBI: The hydrochloride salt of diphenylpyraline. A sedating antihistamine, it is used as the hydrochloride for the symptomatic relief of allergic conditions including rhinitis and hay fever, and in pruritic skin disorders.
General Description
Diphenylpyr alinehydrochloride, 4-(diphenylmethoxy)-1-methylpiperidinehydrochloride (Hispril, Diafen) is a white or slightly offwhitecrystalline powder that is soluble in water or alcohol.Diphenylpyraline is structurally related to diphenhydraminewith the aminoalkyl side chain incorporated in a piperidinering. It is a potent antihistaminic, and the usual dose is 2 mg3 or 4 times daily.
Diphenylpyraline Hydrochloride Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| VASUDHA PHARMA CHEM LIMITED | +91-91-4044763666 +91-9396659284 | Telangana, India | 102 | 58 | Inquiry |
| Saburi Life Sciences | +91-9052929666 +91-9177339666 | Hyderabad, India | 91 | 58 | Inquiry |
| Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| LEAP CHEM CO., LTD. | +86-852-30606658 | China | 24738 | 58 | Inquiry |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | China | 9338 | 55 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |