O-ACETYLSALICYLOYL CHLORIDE

- CAS No.
- 5538-51-2
- Chemical Name:
- O-ACETYLSALICYLOYL CHLORIDE
- Synonyms
- SKL1282;ASPIRIN CHLORIDE;AKOS BBS-00003925;2-(Chlorocarbonyl);O-ACETYLSALICYLOYL C;o-Acetylsalicychloride;Acetylsalicoyl chloride;O-Acetoxybenzoylchloride;ACETYLSALICYLOYL CHLORIDE;2-ACETOXYBENZOYL CHLORIDE
- CBNumber:
- CB9446371
- Molecular Formula:
- C9H7ClO3
- Molecular Weight:
- 198.6
- MOL File:
- 5538-51-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2025/1/27 9:38:02
Melting point | 45-49 °C (lit.) |
---|---|
Boiling point | 107-110 °C/0.1 mmHg (lit.) |
Density | 1.3219 (rough estimate) |
refractive index |
n |
Flash point | >230 °F |
storage temp. | Refrigerator |
solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
form | powder to lump |
color | White to Orange to Green |
Water Solubility | Soluble in toluene. Reacts with water. |
Sensitive | Moisture Sensitive |
BRN | 880372 |
Stability | Moisture Sensitive |
CAS DataBase Reference | 5538-51-2(CAS DataBase Reference) |
NIST Chemistry Reference | Acetylsalicyloyl chloride(5538-51-2) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS05 |
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Signal word | Danger | |||||||||
Hazard statements | H314 | |||||||||
Precautionary statements | P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363 | |||||||||
Hazard Codes | C,Xi | |||||||||
Risk Statements | 22-34-37-29 | |||||||||
Safety Statements | 26-36/37/39-45 | |||||||||
RIDADR | UN 3261 8/PG 2 | |||||||||
WGK Germany | 3 | |||||||||
F | 3-10-21 | |||||||||
Hazard Note | Irritant/Corrosive/Moisture Sensitive | |||||||||
HazardClass | 8 | |||||||||
PackingGroup | II | |||||||||
HS Code | 29163900 | |||||||||
NFPA 704 |
|
O-ACETYLSALICYLOYL CHLORIDE price More Price(6)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 165190 | O-Acetylsalicyloyl chloride 95% | 5538-51-2 | 5G | ₹1818.6 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 165190 | O-Acetylsalicyloyl chloride 95% | 5538-51-2 | 5G | ₹1818.6 | 2022-06-14 | Buy |
Sigma-Aldrich | 165190 | O-Acetylsalicyloyl chloride 95% | 5538-51-2 | 25G | ₹7902.25 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 165190 | O-Acetylsalicyloyl chloride 95% | 5538-51-2 | 25G | ₹7902.25 | 2022-06-14 | Buy |
TCI Chemicals (India) | A1917 | O-Acetylsalicyloyl Chloride | 5538-51-2 | 5G | ₹2100 | 2022-05-26 | Buy |
O-ACETYLSALICYLOYL CHLORIDE Chemical Properties,Uses,Production
Chemical Properties
yellow to light orange chunks
Uses
O-Acetylsalicyloyl chloride was used in the synthesis of enantiomerically pure bidentate heteroorganic ligands built on simple achiral skeletons and containing an aziridine moiety. It was used in the general synthesis of acetoxybenzamides. It was used in the chemical synthesis of 2,2,6,6-tetramethyl-1-piperidinyloxy(TEMPO)-aspirin conjugate via condensation reaction with 4-hydroxy-TEMPO. It was used as reagent in acylation of cyclobutenediones.
Purification Methods
Check first the IR to see if an OH frequency is present. If so, some free acid is present. Then reflux with acetyl chloride for 2-3hours and fractionate at high vacuum. The distillate should crystallise. It can be recrystallised from hexane or *C6H6 (m 60o, sintering at 52o). [Riegel & Wittcoff J Am Chem Soc 64 486 1942, Beilstein 10 H 86, 10 I 43, 10 II 55, 10 III 151, 10 IV 169.]
O-ACETYLSALICYLOYL CHLORIDE Preparation Products And Raw materials
Raw materials
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chevron_rightSupplier | Tel | Country | ProdList | Advantage | Inquiry |
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GOALSY PHARMA | +91-8247562464 +91-9885583385 | Hyderabad, India | 475 | 58 | Inquiry |
Retrosynth Finechem Pvt Ltd | +91-9227230203 +91-9227230203 | Gujarat, India | 26 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6257 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6768 | 58 | Inquiry |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | China | 5868 | 58 | Inquiry |
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | China | 29730 | 60 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49732 | 58 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29808 | 58 | Inquiry |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30231 | 58 | Inquiry |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | China | 34563 | 58 | Inquiry |
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