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Trimethylacetic anhydride

CAS No.: 1538-75-6

Chemical Name:: Trimethylacetic anhydride

Synonyms: PIVALIC ANHYDRIDE;Bis(2,2-dimethylpropionic)anhydride;Pivalic anydride;Bis(pivalic)anhydride;Pivalic acid anhydride;2,2-Dimethylpropanoicanhydride;2,2-dimethylpropanoyl 2,2-dimethylpropanoate;Pivolic Anhydride;Dipivalic anhydride;PivalicAnhydride>

CBNumber:: CB9470666

Molecular Formula:: C10H18O3

Molecular Weight:: 186.25

MOL File:: 1538-75-6.mol

MSDS File:: SDS

Modify Date:: 2024/7/12 17:58:41

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Trimethylacetic anhydride Properties

Boiling point	193 °C(lit.)
Density	0.918 g/mL at 25 °C(lit.)
vapor pressure	62.1Pa at 25℃
refractive index	n20/D 1.409(lit.)
Flash point	135 °F
storage temp.	Inert atmosphere,Room Temperature
solubility	Miscible with acetonitrile.
form	Liquid
color	Clear colorless
Sensitive	Moisture Sensitive
BRN	386552
InChI	InChI=1S/C10H18O3/c1-9(2,3)7(11)13-8(12)10(4,5)6/h1-6H3
InChIKey	PGZVFRAEAAXREB-UHFFFAOYSA-N
SMILES	C(C)(C)(C)C(=O)OC(=O)C(C)(C)C
LogP	2.15
CAS DataBase Reference	1538-75-6(CAS DataBase Reference)
EPA Substance Registry System	Propanoic acid, 2,2-dimethyl-, anhydride (1538-75-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS05

Signal word

Danger

Hazard statements

H226-H314

Precautionary statements

P210-P233-P240-P280-P303+P361+P353-P305+P351+P338

Hazard Codes

Risk Statements

Safety Statements

26-36/37/39-45

RIDADR

UN 2920 8/PG 2

WGK Germany

9-13-21

TSCA

Yes

HazardClass

PackingGroup

HS Code

29159000

NFPA 704

	2
3		0

Trimethylacetic anhydride price More Price(5)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ALFA India	ALF-B22983-36	Trimethylacetic anhydride, 99%	1538-75-6	500g	₹34439	2022-05-26	Buy
ALFA India	ALF-B22983-22	Trimethylacetic anhydride, 99%	1538-75-6	100g	₹13046	2022-05-26	Buy
ALFA India	ALF-B22983-14	Trimethylacetic anhydride, 99%	1538-75-6	25g	₹4182	2022-05-26	Buy
TCI Chemicals (India)	P1414	Pivalic Anhydride min. 98.0 %	1538-75-6	25ML	₹4500	2022-05-26	Buy
TCI Chemicals (India)	P1414	Pivalic Anhydride min. 98.0 %	1538-75-6	250ML	₹22900	2022-05-26	Buy

Product number	Packaging	Price	Buy
ALF-B22983-36	500g	₹34439	Buy
ALF-B22983-22	100g	₹13046	Buy
ALF-B22983-14	25g	₹4182	Buy
P1414	25ML	₹4500	Buy
P1414	250ML	₹22900	Buy

Trimethylacetic anhydride Chemical Properties,Uses,Production

Description

Trimethylacetic anhydride is a pivalic acid derivative that is used in organic synthesis. The compound's reaction mechanism is believed to be the formation of an alkanoic acid, which reacts with a hydroxyl group to form an anhydride. Trimethyl acetic anhydride has been shown to have pharmacokinetic properties and can be used as a nonsteroidal anti-inflammatory drug. This compound has also been found to have a matrix effect on crystalline cellulose and is capable of forming nitrogen-containing carboxylic acids.

Chemical Properties

clear colourless liquid

Uses

Trimethylacetic anhydride was used:

in solid-phase oligonucleotide synthesis
in kinetic resolution of racemic 2-hydroxy-γ-butyrolactones with diphenylacetic acid
as acylation and esterification reagent for anilines
as acylation and esterification reagent for phenols

Trimethylacetic anhydride Preparation Products And Raw materials

Raw materials

Preparation Products

1-BOC-1,10-DIAMINODECANE CENTIFOLYL N-T-BOC-PYRROLE 1-BOC-1,12-DIAMINODODECANE N-(2-HYDROXYETHYL)-2,2-DIMETHYLPROPANAMIDE(WXC08449)

N-(pivaloyloxy)benzamide N-Boc-4-ethyl-DL-phenylalanine

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Trimethylacetic anhydride Suppliers

Global( 246)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
REDDY N REDDY PHARMACEUTICALS	+91-9848096759 +91-9848096759	Hyderabad, India	1989	58	Inquiry
JSK Chemicals	+919879767970	Gujarat, India	3756	58	Inquiry
Sri Neelima Laboratories	+91-7981733602 +91-9849736989	Telangana, India	205	58	Inquiry
TCI Chemicals (India) Pvt. Ltd.	1800 425 7889	New Delhi, India	6778	58	Inquiry
Alfa Aesar	1 800 209 7001	Maharashtra, India	6913	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
Reddy N Reddy Pharmaceuticals	+91 (40) 2307-5686 / +91 98480-96759 / +91 98481-96759	New Delhi, India	254	0	Inquiry
Handan Huajun chemicals Co.,Ltd	+86-0310-8166573 +8618630058311	China	29	58	Inquiry
Shaanxi Haibo Biotechnology Co., Ltd	+undefined18602966907	China	1000	58	Inquiry

Supplier	Advantage
REDDY N REDDY PHARMACEUTICALS	58
JSK Chemicals	58
Sri Neelima Laboratories	58
TCI Chemicals (India) Pvt. Ltd.	58
Alfa Aesar	58
CLEARSYNTH LABS LTD.	58
A.J Chemicals	58
Reddy N Reddy Pharmaceuticals	0
Handan Huajun chemicals Co.,Ltd	58
Shaanxi Haibo Biotechnology Co., Ltd	58

Trimethylacetic anhydride Spectrum

TRIMETHYLACETIC ANHYDRIDE(1538-75-6)MS TRIMETHYLACETIC ANHYDRIDE(1538-75-6)¹HNMR TRIMETHYLACETIC ANHYDRIDE(1538-75-6)¹³CNMR TRIMETHYLACETIC ANHYDRIDE(1538-75-6)IR1 TRIMETHYLACETIC ANHYDRIDE(1538-75-6)Raman

1538-75-6(Trimethylacetic anhydride)Related Search:

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Isobutyl isobutyrate ISOBUTYRIC ACID N-PROPYL ESTER VALERIC ANHYDRIDE Propionic anhydride Methyl trimethylacetate

Isobutyl acetate Isobutyl formate TRIMETHYLACETIC ANHYDRIDE

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2,2-DIMETHYLPROPIONIC ANHYDRIDE 2,2-Dimethylpropionic anhydride, Pivalic anhydride Bis(2,2-dimethylpropionic acid)anhydride Bis(pivalic acid)anhydride Dipivalic anhydride Trimethylacetic anhydride,99% Propanoic acid, 2,2-dimethyl-, anhydride Propanoicacid,2,2-dimethyl-,anhydride Trimethylacetic anhydride,2,2-Dimethylpropionic anhydride, Pivalic anhydride Trimethylacetic anhy TriMethylacetic anhydride, 99% 50ML 2,2-Dimethylpropionic Anhydride Trimethylacetic Anhydride PIVALIC ANHYDRIDE FOR SYNTHESIS Propanoic acid,2,2-dimethyl-, 1,1'-anhydride TriMethylacetic anhydride 99% Pivalic anhydride, >=98.0% (GC) TRIMETHYLACETIC ACID ANHYDRIDE TRIMETHYLACETIC ANHYDRIDE 1,1-Dimethylpropanoic anhydride 2,2-dimethyl-propanoicacianhydride BIS(TRIMETHYLACETIC) ANHYDRIDE 2,2-DIMETHYLPROPIONIC ACID ANHYDRIDE PivalicAnhydride> Adefovir Dipivoxil Impurity 15 (Pivalic Anhydride) Adefovir Impurity 36 Trimethylacetic Anhydride1538-75-6 Adefovir Dipivoxyl Impurity 18 TIANFU-CHEM -TRIMETHYLACETIC ANHYDRIDE Bis(2,2-dimethylpropionic)anhydride Bis(pivalic)anhydride Pivalic acid anhydride Pivalic anydride 2,2-Dimethylpropanoicanhydride PIVALIC ANHYDRIDE 2,2-dimethylpropanoyl 2,2-dimethylpropanoate Pivalic anhydride (7CI, 8CI) Pivolic Anhydride Pivalic anhydride,98% 1538-75-6 C10H18O3 CH33CCO2O Carbonyl Compounds Carboxylic Acid Anhydrides Building Blocks Organic Building Blocks Aliphatics, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals Aliphatics Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals