Chinese english Japanese Germany Korea
ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >GPCR & G Protein >LPA Receptor Antagonist >KI16425

KI16425

KI16425 Structure
CAS No.
355025-24-0
Chemical Name:
KI16425
Synonyms
CS-88;KI-6425;Debio 0719;Ki16425, >=98%;KI16425 USP/EP/BP;KI-16425; KI 16425;Ki16425 (Debio 0719);Ki16425, 10 mM in DMSO;KI16425;KI-16425; KI 16425;Ki 16425, competitive, potent and reversible antagonist to LPA
CBNumber:
CB9497429
Molecular Formula:
C23H23ClN2O5S
Molecular Weight:
474.96
MOL File:
355025-24-0.mol
MSDS File:
SDS
Modify Date:
2025/1/27 9:38:02
Request For Quotation

KI16425 Properties

Melting point 59.5-60.5 °C
Boiling point 623.7±55.0 °C(Predicted)
Density 1.353
storage temp. -20°C
solubility DMSO: 16 mg/mL
form solid
pka 4.32±0.10(Predicted)
color white

SAFETY

Risk and Safety Statements

Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
HS Code  29349990

KI16425 price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SML0971 Ki 16425 ≥98% (HPLC) 355025-24-0 5MG ₹11571.93 2022-06-14 Buy
Sigma-Aldrich(India) SML0971 Ki 16425 ≥98% (HPLC) 355025-24-0 25MG ₹46731.53 2022-06-14 Buy
Product number Packaging Price Buy
SML0971 5MG ₹11571.93 Buy
SML0971 25MG ₹46731.53 Buy

KI16425 Chemical Properties,Uses,Production

Description

Lysophosphatidic acid (LPA) is a bioactive lipid mediator that signals through five distinct G protein-coupled receptors (LPA1-5). Ki16425 is a LPA receptor antagonist with selectivity for LPA1 and LPA3. It exhibits Ki values of 0.34, 6.5, and 0.93 μM for the human LPA1, LPA2, and LPA3 receptors, respectively, as determined by measuring inositol phosphate production in RH7777-transfected cells. Ki1642, at 10 μM, significantly blocks the response of a variety of cancer cell lines to LPA-induced cell migration.

Uses

Ki16425 is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3.

Biochem/physiol Actions

Ki 16425 possesses a short-lived inhibitory activity. It has been studied that Ki 16425 is effective in the inhibition of neuropathic pain‐like behaviors.

KI16425 Preparation Products And Raw materials

Raw materials

Preparation Products

KI16425 Suppliers

Global( 115)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6257 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6100 58 Inquiry
Capot Chemical Co.,Ltd. +86-（0）57185586718 +86-13336195806 China 29730 60 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 33024 60 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49732 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 32197 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30230 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 22854 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10473 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6391 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
A.J Chemicals 58
Capot Chemical Co.,Ltd. 60
ATK CHEMICAL COMPANY LIMITED 60
CONIER CHEM AND PHARMA LIMITED 58
TargetMol Chemicals Inc. 58
Career Henan Chemica Co 58
Dideu Industries Group Limited 58
Zhejiang J&C Biological Technology Co.,Limited 58
InvivoChem 58

KI16425 Spectrum

KI16425(355025-24-0)1HNMR

355025-24-0(KI16425)Related Search:

Tofacitinib citrate 42-(Dimethylphosphinate)rapamycin MG-132 PD 98059 LY 2157299
Olaparib 3,5-DIMETHYL-4-ISOXAZOLEMETHANAMINE KI16425 N-(4-ISOXAZOLYL)FORMAMIDE 4-ISOXAZOLAMINE
chevron_left

1of2

chevron_right
3-[[[4-[4-[[[1-(2-chlorophenyl)ethoxy]carbonyl]amino]-3-methyl-5-isoxazoly]phenyl]methyl]thio]-propanoic acid 3-[[[4-[4-[[[1-(2-Chlorophenyl)ethoxy]carbonyl]amino]-3-methyl-5-isoxazolyl]phenyl]methyl]thio]propanoic acid KI-6425 3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)-3-methylisoxazol-5-yl)benzylthio)propanoic acid Ki16425, >=98% KI16425;KI-16425; KI 16425 3-[[4-[4-[1-(2-chlorophenyl)ethoxycarbonylamino]-3-methyl-isoxazol-5-yl]phenyl]methylsulfanyl]propanoic acid 3-((4-(4-(((1-(2-Chlorophenyl)ethoxy)carbonyl)amino)-3-methylisoxazol-5-yl)benzyl)thio)propano CS-88 KI-16425; KI 16425 Ki 16425, 98%, competitive, potent and reversible antagonist to LPA Debio 0719 Propanoic acid, 3-[[[4-[4-[[[1-(2-chlorophenyl)ethoxy]carbonyl]amino]-3-methyl-5-isoxazolyl]phenyl]methyl]thio]- KI16425 USP/EP/BP Ki16425 (Debio 0719) Ki 16425, competitive, potent and reversible antagonist to LPA Ki16425, 10 mM in DMSO 355025-24-0 Inhibitors