Bepridil hydrochloride
- CAS No.
- 74764-40-2
- Chemical Name:
- Bepridil hydrochloride
- Synonyms
- angopril;Unii-4W2p15D93m;Bepridil hydrochloride;UEECHQPWQHYEDE-UHFFFAOYSA-N;Bepridil hydrochloride salt;Bepridil hydrochloride hydrate;Bepridil hydrochloride USP/EP/BP;l)-,monohydrochloride,monohydrate;1-Isobutoxy-2-pyrrolidino-3-(N-benzylanilino)propane hydrochloride;N-Benzyl-N-(3-isobutoxy-2-pyrrolidin-1-yl-propyl)anilinehydrochloride
- CBNumber:
- CB9497924
- Molecular Formula:
- C24H37ClN2O2
- Molecular Weight:
- 421.01578
- MOL File:
- 74764-40-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/3/19 15:37:50
| Melting point | 91 ±2° |
|---|---|
| storage temp. | Desiccate at RT |
| solubility | Soluble in DMSO (up to 25 mg/ml) or ethanol (up to 25 mg/ml) |
| form | powder |
| color | white |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month. |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS08,GHS07 |
|---|---|
| Signal word | Danger |
| Hazard statements | H317-H332-H334 |
| Precautionary statements | P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P261-P271-P304+P340-P312-P261-P285-P304+P341-P342+P311-P501 |
| WGK Germany | 2 |
| RTECS | UY1162000 |
| Toxicity | LD50 in mice (mg/kg): 1955 orally, 23.5 i.v. (Mauvernay, 1978) |
Bepridil hydrochloride Chemical Properties,Uses,Production
Uses
antineoplastic, alkylating agent
Definition
ChEBI: The hydrochloride monohydrate of bepridril.
General Description
Bepridil hydrochloride,β-[(2-methylpropoxy)methyl]-N-phenyl-N-(phenylmethyl)-1-pyrrolidineethylamine hydrochloride (Vascor), is a secondgenerationalkylamine-type channel blocker, structurallyunrelated to the dihydropyridines. Its actions are less specificthan those of the three prototypical channel blockers,verapamil, diltiazem, and nifedipine. In addition to being aCa2+ channel blocker, it inhibits sodium flow into the hearttissue and lengthens cardiac repolarization, causing bradycardia.Caution should be used if it is given to a patient withhypokalemia. Bepridil hydrochloride is used for stableangina. The drug has a half-life of 33 hours and is highlybound to protein (99%).
Hazard
Moderately toxic by ingestion.
Bepridil hydrochloride Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | China | 9030 | 58 | Inquiry |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | China | 3136 | 58 | Inquiry |
| LEAPCHEM CO., LTD. | +86-852-30606658 | China | 43348 | 58 | Inquiry |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | China | 33350 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
| Wuhan Huangzhen Biochemical Co., Ltd | 13795480948 13795480948 | China | 4958 | 58 | Inquiry |
| Shanghai Aladdin Biochemical Technology Co.,Ltd. | +86-18521732826 | China | 48467 | 58 | Inquiry |
| RD International Technology Co., Limited | 18024082417 | China | 9274 | 58 | Inquiry |
| Nantong Hi-Future Biotechnology Co., Ltd | 18051384581 | China | 3058 | 58 | Inquiry |