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Fotemustine

Fotemustine Structure
CAS No.
92118-27-9
Chemical Name:
Fotemustine
Synonyms
S-10036;Muphoran;Ccris 6337;Fotemustin;FOTEMUSTINE;Fotemustina;Fotemustene;Fotemustinum;Mustophorane;Fotemustinum [latin]
CBNumber:
CB9666315
Molecular Formula:
C9H19ClN3O5P
Molecular Weight:
315.69
MOL File:
92118-27-9.mol
MSDS File:
SDS
Modify Date:
2023/5/4 17:34:43

Fotemustine Properties

Melting point 85°
Density 1.37±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility H2O: ≥1mg/mL
form powder
pka 9.47±0.46(Predicted)
color light yellow
CAS DataBase Reference 92118-27-9(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Warning
Hazard statements  H351
Precautionary statements  P281
Hazard Codes  Xn
Risk Statements  40
Safety Statements  36/37
WGK Germany  3

Fotemustine Chemical Properties,Uses,Production

Description

Fotemustine is a new nitrosourea reportedly effective in the treatment of disseminated malignant melanoma, with only mild hematological toxicity. Response rate is generally lower in patients with colonic, breast, head and neck cancer.

Uses

Fotemustine is used in patients malignant gliomas to improve the efficacy of radiotherapy. Used in the treatment of glioblastomas.

Fotemustine Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 70)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 24639 58 Inquiry
Dayang Chem (Hangzhou) Co.,Ltd. 571-88938639 +8617705817739 China 52861 58 Inquiry
Hefei TNJ Chemical Industry Co.,Ltd. 0551-65418684 +8618949823763 China 25363 58 Inquiry
PT CHEM GROUP LIMITED +86-85511178 +86-85511178 China 35426 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
1-(2-chloroethyl)-3-(1-diethoxyphosphorylethyl)-1-nitrosourea FOTEMUSTINE Fotemustin Muphoran S-10036 Phosphonic acid, P-[1-[[[(2-chloroethyl)nitrosoamino]carbonyl]amino]ethyl]-, diethyl ester [1-[[[(2-Chloroethyl)nitlx~amino]carbonyl]amino]ethyl]phosphonic acid diethyl ester [1-[[[(2-Chloroethyl)nitrosoamino]carbonyl]amino]ethyl]phosphonic acid diethyl ester (+-)-Diethyl (1-(3-(2-chloroethyl)-3-nitrosoureido)ethyl)phosphonate Ccris 6337 Diethyl-1-(3-(2-chloroethyl)-3-nitrosoureido)ethylphosphonate Fotemustina Fotemustina [spanish] Fotemustinum Fotemustinum [latin] Phosphonic acid, (1-((((2-chloroethyl)nitrosoamino)carbonyl)amino)ethyl)-, diethyl ester diethyl [(1S)-1-{[N-(2-chloroethyl)-N'-oxohydrazinecarbonyl]aMino}ethyl]phosphonate Mustophorane P-[1-[[[(2-Chloroethyl)nitrosoamino]carbonyl]amino]ethyl]-phosphonic acid diethyl ester Fotemustene Fotemustine USP/EP/BP 92118-27-9 C9H19ClN3O5P