Bendamustine
![Bendamustine Structure](CAS/GIF/97832-05-8.gif)
- CAS No.
- 97832-05-8
- Chemical Name:
- Bendamustine
- Synonyms
- Bendamustine;Bendamustine USP/EP/BP;Phenol,5-iodo-7-methyl-;4-[5-[Bis(2-chloroethyl)amino]-1-methyl-benzimidazol-2-yl]butyric acid hydrochloride
- CBNumber:
- CB1947357
- Molecular Formula:
- C16H21Cl2N3O2.HCl
- Molecular Weight:
- 394.72
- MOL File:
- 97832-05-8.mol
- MSDS File:
- SDS
Bendamustine Chemical Properties,Uses,Production
Enzyme inhibitor
This nitrogen mustard and anticancer drug (FWfree-acid = 358.26 g/mol; CAS 16506-27-7), also known by its code name SDX-105, its trade names Treanda?, Treakisym?, Ribomustin?, and Levact?, as well as by its systematic name 4-[5-[bis (2-chloroethyl) amino]-1-methylbenzimidazol-2- yl]butanoic acid, is a relatively nonspecific DNA alkylating agent that causes intra- and inter-strand cross-links. Bendamustine is used in the treatment of chronic lymphocytic leukemia (CLL), Hodgkin’s disease, non- Hodgkin’s lymphoma, multiple myeloma and lung cancer. Pharmacokinetics: After intravenous infusion, >95% of the drug becomes protein-bound, mainly to albumin; however, only free bendamustine is active. Bendamustine is metabolized by liver cytochrome p450, and elimination (renal) is biphasic, with an initial half-life of 6–10 minutes and a terminal half-life of approximately 30 minutes.
Bendamustine Preparation Products And Raw materials
Raw materials
Preparation Products
Bendamustine Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
J S LABS | +91-7330612784 +91-7330612784 | Tamil Nadu, India | 160 | 58 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29894 | 58 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
SIMAGCHEM CORP | +86-13806087780 | China | 17367 | 58 | Inquiry |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 24330 | 58 | Inquiry |
AFINE CHEMICALS LIMITED | +86-0571-85134551 | China | 15395 | 58 | Inquiry |
sgtlifesciences pvt ltd | +8617013299288 | China | 12382 | 58 | Inquiry |
Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418684 +8618949823763 | China | 25363 | 58 | Inquiry |
Watson Biotechnology Co.,Ltd | +86-18186686046 +86-18186686046 | China | 5853 | 58 | Inquiry |
Nanjing XiZe Biotechnology CO., Ltd. | 025-66023220 0086-15250997978 | China | 7774 | 55 | Inquiry |
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