ChemicalBook > Product Catalog >API >Antineoplastic agents >Alkylating antineoplastic >Bendamustine hydrochloride
Bendamustine hydrochloride
- CAS No.
- 3543-75-7
- Chemical Name:
- Bendamustine hydrochloride
- Synonyms
- EP3101;Treanda;SDX 105;DD6304600;CYTOSTASAN;Ribomustin;ZIMET-33/93;Cytostasane;Bendamustina;CytostasanHCl
- CBNumber:
- CB0777896
- Molecular Formula:
- C16H22Cl3N3O2
- Molecular Weight:
- 394.72
- MOL File:
- 3543-75-7.mol
- Modify Date:
- 2024/6/3 14:46:32
| Melting point | 149-151°C |
|---|---|
| storage temp. | room temp |
| solubility | H2O: >30mg/mL |
| form | powder |
| color | off-white |
| Merck | 14,1034 |
| InChIKey | ZHSKUOZOLHMKEA-UHFFFAOYSA-N |
| CAS DataBase Reference | 3543-75-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS08 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Symbol(GHS) | GHS06,GHS08 |
|||||||||
| Signal word | Danger | |||||||||
| Signal word | Danger | |||||||||
| Hazard statements | H301-H341-H351-H361fd | |||||||||
| Hazard statements | H301-H341-H351-H361fd | |||||||||
| Precautionary statements | P201-P202-P264-P270-P280-P301+P310 | |||||||||
| Precautionary statements | P201-P202-P264-P270-P280-P301+P310 | |||||||||
| Hazard Codes | T,Xn | |||||||||
| Risk Statements | 60-61-22-40 | |||||||||
| Safety Statements | 36-37 | |||||||||
| RIDADR | UN 2811 6.1 / PGIII | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | DE1590000 | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29339900 | |||||||||
| Toxicity | LD50 (monohydrate) in mice, rats (mg/kg): 400-500, 200-300 orally; 80, 40 i.v. (Horn) | |||||||||
| NFPA 704 |
|
Bendamustine hydrochloride price More Price(2)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | B5437 | Bendamustine hydrochloride hydrate ≥98% (HPLC) | 3543-75-7 | 5MG | ₹15328.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | B5437 | Bendamustine hydrochloride hydrate ≥98% (HPLC) | 3543-75-7 | 25MG | ₹61258.68 | 2022-06-14 | Buy |
Bendamustine hydrochloride Chemical Properties,Uses,Production
Chemical Properties
Pale Brown Crystals
Uses
Bendamustine hydrochloride hydrate has been used as:
- a chemotherapy agent for chronic lymphocytic leukemia (CLL) samples to monitor spliced and unspliced gene expression
- an inhibitor to E3 ubiquitin-protein ligase RNF3 (HOIP) in?matrix-assisted laser desorption ionization time-of-flight mass spectrometry?(MALDI-TOF) assay
- a cytotoxic chemotherapeutic drug in high-throughput screening to test interaction with BAY87-2243
General Description
Bendamustine comprises 2-chloroethylamine alkylating group, a butyric acid side chain and a benzimidazole ring in its structure and is a nitrogen mustard. It is catabolized in the liver by the enzyme cytochrome P450 1A2 into γ hydroxyl-bendamustine and N-desmethyl-bendamustine.
Biological Activity
Cytostatic agent that displays activity in non-Hodgkin's lymphomas. Exhibits bifunctionality; combines DNA alkylating properties with those of purine analogs.
Bendamustine hydrochloride Preparation Products And Raw materials
Raw materials
Pentanoic acid, 5-[(2,4-dinitrophenyl)methylamino]-5-oxo-, methyl ester
Pentanoic acid, 5-[(2,4-dinitrophenyl)amino]-5-oxo-, methyl ester
isopropyl 4-(1-methyl-5-nitro-1H-benzo[d]imidazol-2-yl)butanoate
5-[Bis(2-chloroethyl)aMino]-1-Methyl-1H-benziMidazole-2-butanoic Acid Methyl Ester
1H-Benzimidazole-2-butanoic acid, 5-[bis(2-hydroxyethyl)amino]-1-methyl-, 1-methylethyl ester
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Global( 401)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| SGMR PHARMACEUTICALS PVT LTD | +91-9032001889 +91-9032001889 | Telangana, India | 83 | 58 | Inquiry |
| Dr. Reddy's Laboratories Ltd | +91-4049002900 +91-4049002900 | Hyderabad, India | 165 | 58 | Inquiry |
| Shree HariKrishna Pharmaceuticals | +91-9925611910 +91-9925611910 | Gujarat, India | 16 | 58 | Inquiry |
| Hetero Drugs Limited | +91-4023704923 +91-4023704923 | Telangana, India | 296 | 58 | Inquiry |
| Shilpa Medicare Limited (SML) | +91-8532238704 +91-9320649838 | Karnataka, India | 61 | 58 | Inquiry |
| Vannsh Life Sciences Pvt Ltd | +91-4023555246 +91-9642555246 | Hyderabad, India | 15 | 58 | Inquiry |
| Aavyan Labs | +91-9652399498 +91-9652399498 | Telangana, India | 60 | 58 | Inquiry |
| Salvavidas Pharmaceutical Pvt., Ltd. | +91-2612538898 +91-9327127459 | Gujarat, India | 34 | 58 | Inquiry |
| Basil Drugs AND Pharmaceuticals Pvt Ltd | +91-2249700250 +91-9619320820 | Mumbai, India | 108 | 58 | Inquiry |
| Rivashaa Agrotech Biopharma Pvt. Ltd. | +91-26463395 +91-7926462688 | Gujarat, India | 1615 | 58 | Inquiry |
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3543-75-7(Bendamustine hydrochloride)Related Search:
BroMo Prasugrel IMpurity
5-[(2-Chloroethyl)(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid 1-Methylethyl Ester
5-[(2-Chloroethyl)(2-hydroxyethyl)aMino]-1-Methyl-1H-benziMidazole-2-butanoic Acid
5-[bis-(2-Chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester
Aprepitant
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1-methyl-5-bis(2-chloroethyl)amino-2-benzimidazolinebutryricacihydrochlor
gamma(1-methyl-5-bis(beta-chloraethyl)aminobenzimidazoyl-2)buttersaeurehydro
BENDAMUSTINE HCL
CytostasanHCl
bendamustine hydrochloride
BENDAMUSTIN HYDROCHLORIDE
CYTOSTASAN
1-methyl-5-bis(2-chloroethyl)amino-2-benzimidazolinebutryric acid hydrochloride
4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid hydrochloride
1H-Benzimidazole-2-butanoicacid,5-[bis(2-chloroethyl)amino]-1-methyl-,hydrochloride
ZIMET-33/93
BendaMustine hydrochloride hydrate
4-(5-(Bis(2-chloroethyl)aMino)-1-Methyl-2,3-dihydro-1H-benzo[d]iMidazol-2-yl)butanoic acid hydrochloride
4-(6-(bis(2-chloroethyl)aMino)-1-Methyl-1H-benzo[d]iMidazol-2-yl)butanoic acid
BendaMustine Hydrochloride (SDX-105)
5-[Bis(2-chloroethyl)-amino]-1-methyl-1H-benzimidazole-2-butanoic Acid Hydrochloride
Ribomustin
Treanda
Bendamustinum
Bendamustinhydrochlorid
BendaMustin HCl
SDX 105
4-(5-(bis(2-chloroethyl)aMino)-1-Methyl-1H-benzo[d]iMidazol-2-yl)butanoic acid hydrochloride
BendaMustine HCl USP
Bendamustine HCl(SDX-105)
5-[bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid,hydrochloride (1:1)
SDX-105 (Cytostasane) HCl
1H-Benzimidazole-2-butanoic acid, 5-[bis(2-chloroethyl)amino]-1-methyl monohydrochloride
EP3101
bendamustine HCl API
Bendamustina
DD6304600
SDX-105 Ribomustin.
TREANDA;BENDAMUSTINUM;BENDAMUSTINA;DD6304600;SDX-105 RIBOMUSTIN.
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3543-75-7
C16H213N3O2HCl
C16H22Cl3N3O2
C16H21Cl2N3O2HClxH2O
C16H21Cl2N3O2ClHH2O
API
Amines
Heterocycles