ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Neuronal Signaling >5-HT Receptor Inhibitor >Duloxetine hydrochloride
Duloxetine hydrochloride
- CAS No.
- 136434-34-9
- Chemical Name:
- Duloxetine hydrochloride
- Synonyms
- DULOXETINE HCL;Duloxetime;DuL;CS-488;LY-248686;LY-248686 HCl;S-Duloxetine HCl;oxetine HydrochL;(RS)Duloxetine HCl;Duloxetine Pellets
- CBNumber:
- CB7724192
- Molecular Formula:
- C18H20ClNOS
- Molecular Weight:
- 333.88
- MOL File:
- 136434-34-9.mol
- Modify Date:
- 2024/4/25 17:59:01
| Melting point | 118-122°C |
|---|---|
| Flash point | 9℃ |
| storage temp. | room temp |
| solubility | H2O: soluble5mg/mL (clear solution, warmed) |
| pka | pKa in DMF-water (66:34): 9.6(at 25℃) |
| form | powder |
| color | white to beige |
| optical activity | [α]/D +116 to +125°, c = 1 in methanol |
| Merck | 14,3465 |
| InChI | InChI=1/C18H19NOS.ClH/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16;/h2-10,13,17,19H,11-12H2,1H3;1H/t17-;/s3 |
| InChIKey | BFFSMCNJSOPUAY-VOPAOICTNA-N |
| SMILES | C1(=CC=CS1)[C@H](CCNC)OC1=CC=CC2=CC=CC=C12.Cl |&1:5,r| |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P301+P312+P330 | |||||||||
| Hazard Codes | Xi,Xn,T,F | |||||||||
| Risk Statements | 36/37/38-22-39/23/24/25-23/24/25-11 | |||||||||
| Safety Statements | 26-36/37-45-16-7 | |||||||||
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | XN0258000 | |||||||||
| HS Code | 29349990 | |||||||||
| NFPA 704 |
|
Duloxetine hydrochloride price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML0474 | (S)-Duloxetine hydrochloride ≥98% (HPLC) | 136434-34-9 | 10MG | ₹7674.93 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML0474 | (S)-Duloxetine hydrochloride ≥98% (HPLC) | 136434-34-9 | 50MG | ₹31262.6 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR1865 | Duloxetine Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material | 136434-34-9 | 500MG | ₹22743.33 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | D-044 | Duloxetine hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant? | 136434-34-9 | 1ML | ₹10041.5 | 2022-06-14 | Buy |
| TCI Chemicals (India) | D4223 | Duloxetine Hydrochloride | 136434-34-9 | 1G | ₹9100 | 2022-05-26 | Buy |
Duloxetine hydrochloride Chemical Properties,Uses,Production
Chemical Properties
White Crystalline Solid
Uses
Duloxetine Hydrochloride acts as an antidepressant and a dual serotonin and norepinephrine reuptake inhibitor (SNRI) (1,2). Exhibits linear pharmacokinetics in mice and is not associated in any drastic changes of blood pressure or heart rate (3).
Definition
ChEBI: A duloxetine hydrochloride in which the duloxetine moiety has S configuration.
General Description
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Duloxetine hydrochloride Preparation Products And Raw materials
Raw materials
Carbamic acid, N-methyl-N-[(3S)-3-(1-naphthalenyloxy)-3-(2-thienyl)propyl]-, ethyl ester
(S)-3-(MethylaMino)-1-(2-thienyl)-1-propanol
Duloxetine Related Compound F (10 mg) ((S)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propan-1-amine hydrochloride)
Duloxetine IMpurity A
(±)-Duloxetine
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Global( 718)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| ANWITA APIS | +919000311012 | Hyderabad, India | 198 | 58 | Inquiry |
| KARPSCHEM LABORATORIES | +91-7249203006 +91-7249203006 | Maharashtra, India | 786 | 58 | Inquiry |
| Styrax Pharma Pvt Ltd | +91-4048583333 +91-9848912103 | Telangana, India | 24 | 58 | Inquiry |
| Aurobindo Pharma Limited | +914066725000 | Telangana, India | 112 | 58 | Inquiry |
| Lupin Ltd | +91-8019896181 +91-8019896181 | Maharashtra, India | 93 | 58 | Inquiry |
| Chemeca Drugs Private Limited (Vegesna Laboratories Pvt Ltd) | +91-8924236065 +91-9951616502 | AndhraPradesh, India | 48 | 58 | Inquiry |
| R L Fine Chem Pvt. Ltd | +91-8042488999 +91-8042488999 | Karnataka, India | 74 | 58 | Inquiry |
| Alembic Pharmaceuticals Limited | +91-2652280880 +91-2652280550 | Gujarat, India | 115 | 58 | Inquiry |
| SOLISOM HEALTHCARE LLP | +918160916499 | Gujarat, India | 14 | 58 | Inquiry |
| Vivimed Labs Ltd | +914066086608 | Telangana, India | 61 | 58 | Inquiry |
136434-34-9(Duloxetine hydrochloride)Related Search:
LY-248686 HCl
(γS)-N-methyl-γ-(1-naphthalenyloxy)-2-thiophenepropanamine, hydrochloride (1:1)
(+)-N-Methyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine hydrochloride
LY-248686 hydrochloride
Duloxetine for system suitability
Duloxetine hydrochloride solution
(S)-N-Methyl-3-(1-naphthalenyloxy)-3-(2-thienyl) propanamine hydrochloride
Methanol（ Test Duloxetine HCl, 1.0 mg/mL as free base）
(S)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-aMine hydrochloride
N-Methyl-gaMa-(1-naphthalenyloxy)-2-thiophenepropa
(+)-(S)-N-Methyl-γ-(1-naphthyloxy)-2-thiophenepropylaMine Hydrochloride
(γS)-N-Methyl-γ-(1-naphthalenyloxy)-2-thiophenepropanaMine Hydrochloride
S-Duloxetine HCl
N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-aMine hydrochloride
(S)-N,N-DiMethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-aMine hydrochloride
(S)-Duloxetine hydrochloride(CyMbalta)
LY-248686
DULOXETINE HYDROCHLORIDE
N-methyl-gamma-(1-naphthalenyloxy)-2-thiophenepropanamine, hydrochloride
(+)-(S)-N-Methyl-g-(1-naphthyloxy)-2-thiophenepropylamine
(gS)-N-Methyl-g-(1-naphthalenyloxy)-2-thiophenepropanamine
(+)-(S)-N-Methyl-g-(1-naphthyloxy-d7)-2-thiophenepropylamine
(gS)-N-Methyl-g-(1-naphthalenyloxy-d7)-2-thiophenepropanamine
DULOXETINE: DULOXETINE HYDROCHLORIDE
N-Methyl-gama-(1-naphthalenyloxy)-2-thiophenepropanamine
(+)-(S)-N-Methyl--(1-naphthyloxy)-2-thiophenepropylamine
(S)-N-Methyl--(1-naphthalenyloxy)-2-thiophenepropanamine
(+)-(S)-N-Methyl--(1-naphthyloxy-d7)-2-thiophenepropylamine
(S)-N-Methyl--(1-naphthalenyloxy-d7)-2-thiophenepropanamine
(RS)Duloxetine HCl
(RS)-DULOXEINEHYDROCHLORIDE
Duloxetine HCl and intermediates
(+)-(S)-n-methyl-g-(1-naphthyloxy)-2-thiophenepropylamine, hydrochloride/duloxetinehcl
Duloxetine hydrochloride ,99%
(S)-DULOXETINE HYDROCHLORIDE
(+)-(S)-N-METHYL-3-(1-NAPHTHYLOXY)--3-(2-THIENYL)PROPANAMINE HYDROCHLORIDE
(S)-N-METHYL-3-(NAPHTHALEN-1-YLOXY)-3-(THIOPHEN-2-YL)PROPAN-1-AMINE HCL
(+)-(S)-N-Methyl-3-(1-naphthyloxy)-3-(2-thienyl)propanamine hydrochloride
CS-488
Duloxetine hydrochloride, ≥98.0%(HPLC)
(S)-DULOXETINE HYDROCHLORIDE;LY-248686 HYDROCHLORIDE
Duloxetine hydrochloride CRS
DuloxetineHydrochloride>
Duloxetine hydrochloridum
Duloxetine for system suitability CRS
oxetine HydrochL
(S)-(+)-N-Methyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine Hydrochloride
Duloxetine hydrochloride USP/EP/BP
Duloxetine Hydrochloride (1.0 mg/mL in Methanol)
methyl[(3S)-3-(naphthalen-1-yloxy)-3-(thiophen-2-
yl)propyl]amine hydrochloride
(+)-(S)-N-Methyl-γ-(1-naphthyloxy)-2-thiophenepropylamine
Duloxetine HCl (LY-248686 HCl)
Duloxetine HydrochlorideQ: What is
Duloxetine Hydrochloride Q: What is the CAS Number of
Duloxetine Hydrochloride Q: What are the applications of
Duloxetine Hydrochloride
Duloxetine for system suitability (Y0001454)
Duloxetine hydrochloride (Y0001453)
Duloxetine Hydrochloride (1229817)
Duloxetime
DULOXETINE HCL