ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Cell Cycle >CDK inhibitors >SNS-032
SNS-032
![SNS-032 Structure](CAS/GIF/345627-80-7.gif)
- CAS No.
- 345627-80-7
- Chemical Name:
- SNS-032
- Synonyms
- CS-202;SNS-032;BMS-387032;BMS-3870032;SNS-032, >=99%;BMS-387032/SNS-032;SNS0032(BMS-387032);SNS-032, 98.5%, a selective CDK2 inhibitor;BMS-387032; SNS 032; SNS032; BMS 387032; BMS387032;1-diMethylethyl)-2-oxazolyl]Methyl]thio]-2-thiazolyl]-
- CBNumber:
- CB51518701
- Molecular Formula:
- C17H24N4O2S2
- Molecular Weight:
- 380.53
- MOL File:
- 345627-80-7.mol
- Modify Date:
- 2023/9/4 16:42:00
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
HS Code | 29349990 |
SNS-032 price More Price(2)
SNS-032 Chemical Properties,Uses,Production
Description
Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. SNS-032 is an ATP-competitive inhibitor of Cdk9, 2, and 7 with IC50 values of 4, 38, and 62 nM, respectively. It is selective for these kinases and displays no additional activity against a panel of 190 kinases (IC50s = >1,000 nM). SNS-032 can block the cell cycle, inhibit transcription, and induce apoptosis in multiple myeloma RPMI-8226 cells with an IC90 value of 0.3 μM. This compound has been shown to induce apoptosis by inhibiting the transcription of the anti-apoptotic proteins, Mcl-1 and XIAP.
Chemical Properties
Off-White Solid
Uses
SNS 032 is a selective inhibitor of Cyclin-dependent Kinase (CDK) 2,7, and 9.
SNS-032 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 162)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | China | 9337 | 55 | Inquiry |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32836 | 60 | Inquiry |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49392 | 58 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29825 | 58 | Inquiry |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | China | 23556 | 58 | Inquiry |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 24200 | 58 | Inquiry |
345627-80-7(SNS-032)Related Search:
3,3-Dimethyl-1-butyne
N-(3-Chlorophenyl)-N'-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-2-thiazolyl]urea methanesulfonate (1:1)
N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide hydrochloride
N-(3-Chlorophenyl)-N'-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-2-thiazolyl]urea
Y27632 (hydrochloride)
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BMS-3870032
N-[5-[(5-tert-Butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide
N-[5-[(5-tert-Butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide SNS-032 (BMS-387032)
N-[5-[(5-tert-butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamid
SNS-032, >=99%
N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide
BMS-387032
4-Piperidinecarboxamide, N-(5-(((5-(1,1-dimethylethyl)-2-oxazolyl)methyl)thio)-2-thiazolyl)-
N-(5-((5-Tert-Butyloxazol-2-yl)methylthio)thiazol-2-yl)piperidine-4-carboxamide
1-diMethylethyl)-2-oxazolyl]Methyl]thio]-2-thiazolyl]-
N-[5-[(5-tert-butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide
N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide(BMS-3870032)
BMS-3870032
SNS0032(BMS-387032)
SNS-032
BMS-387032; SNS 032; SNS032; BMS 387032; BMS387032
CS-202
SNS 032; SNS032; SNS-032; BMS387032; BMS 387032; BMS-387032
SNS-032, 98.5%, a selective CDK2 inhibitor
N-[5-[(5-tert-butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide USP/EP/BP
N-[5-[(5-tert-Butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thia...
BMS-387032/SNS-032
N-(5-(((4-(tert-butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide
345627-80-7
C17H24N4O2S2
Inhibitors
Specific and potent inhibitor of cyclin-dependent kinases (CDK) 2, 7 and 9.
Aromatics
Heterocycles
Intermediates & Fine Chemicals. Sulfur & Selenium Compounds
Pharmaceuticals
Inhibitor of cyclin-dependent kinases (CDK) 2, 7 and 9.