SNS-032
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- ₹9093 - ₹36707.58
- Product name: SNS-032
- CAS: 345627-80-7
- MF: C17H24N4O2S2
- MW: 380.53
- EINECS:
- MDL Number:MFCD09833875
- Synonyms:BMS-3870032 N-[5-[(5-tert-Butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide;N-[5-[(5-tert-Butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide SNS-032 (BMS-387032);N-[5-[(5-tert-butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamid;SNS-032, >=99%;N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide;BMS-387032;4-Piperidinecarboxamide, N-(5-(((5-(1,1-dimethylethyl)-2-oxazolyl)methyl)thio)-2-thiazolyl)-;N-(5-((5-Tert-Butyloxazol-2-yl)methylthio)thiazol-2-yl)piperidine-4-carboxamide
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberSML2218
- Product descriptionSNS-032 ≥98% (HPLC)
- Packaging5MG
- Price₹9093
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML2218
- Product descriptionSNS-032 ≥98% (HPLC)
- Packaging25MG
- Price₹36707.58
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML2218 | SNS-032 ≥98% (HPLC) | 5MG | ₹9093 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML2218 | SNS-032 ≥98% (HPLC) | 25MG | ₹36707.58 | 2022-06-14 | Buy |
Properties
Melting point :171-173 °C
Density :1.28±0.1 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :7.33±0.70(Predicted)
color :White to Off-White
Density :1.28±0.1 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :7.33±0.70(Predicted)
color :White to Off-White
Safety Information
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Description
Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. SNS-032 is an ATP-competitive inhibitor of Cdk9, 2, and 7 with IC50 values of 4, 38, and 62 nM, respectively. It is selective for these kinases and displays no additional activity against a panel of 190 kinases (IC50s = >1,000 nM). SNS-032 can block the cell cycle, inhibit transcription, and induce apoptosis in multiple myeloma RPMI-8226 cells with an IC90 value of 0.3 μM. This compound has been shown to induce apoptosis by inhibiting the transcription of the anti-apoptotic proteins, Mcl-1 and XIAP.Related product price
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Suppliers and manufacturers
career henan chemical co
![N-[5-[(5-tert-butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide](https://img.chemicalbook.com/ProductImageEN/2020-1/small/51bba257-99f7-4c18-849e-273c8fabf0e7.jpg)
CLEARSYNTH LABS LTD.
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ATK CHEMICAL COMPANY LIMITED
Chongqing Chemdad Co., Ltd
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ANHUI WITOP BIOTECH CO., LTD
Dideu Industries Group Limited
₹0.01 /1KG
N-[5-[(5-tert-butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide CAS:345627-80-7
N-[5-[(5-tert-butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide CAS:345627-80-7