N-(3-Chlorophenyl)-N'-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-2-thiazolyl]urea methanesulfonate (1:1)
![N-(3-Chlorophenyl)-N'-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-2-thiazolyl]urea methanesulfonate (1:1) Structure](/CAS/20180906/GIF/1146618-41-8.gif)
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- ₹6420 - ₹25920
- Product name: N-(3-Chlorophenyl)-N'-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-2-thiazolyl]urea methanesulfonate (1:1)
- CAS: 1146618-41-8
- MF: C19H19ClN6O4S3
- MW: 527.03996
- EINECS:
- MDL Number:MFCD16621142
- Synonyms:SNS-314 mesylate, >=98%;N-(3-Chlorophenyl)-N'-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-2-thiazolyl]urea methanesulfonate (1:1);SNS-314 Mesylate;M1-(3-chlorophenyl)-3-(5-(2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl)thiazol-2-yl)urea Mesylate;N-(3-Chlorophenyl)-N'-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-2-thiazolyl]urea methanesulfonate (1:1) SNS-314 Mesylate;1-(3-chlorophenyl)-3-(5-(2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl)thiazol-2-yl)urea methanesulfonate;N-(3-Chlorophenyl)-N'-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-2-thiazolyl]urea methanesulfonate;SNS-314 MESYLATE; SNS314; SNS 314
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberSML2194
- Product descriptionSNS-314 mesylate ≥98% (HPLC)
- Packaging5MG
- Price₹6420
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML2194
- Product descriptionSNS-314 mesylate ≥98% (HPLC)
- Packaging25MG
- Price₹25920
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML2194 | SNS-314 mesylate ≥98% (HPLC) | 5MG | ₹6420 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML2194 | SNS-314 mesylate ≥98% (HPLC) | 25MG | ₹25920 | 2022-06-14 | Buy |
Properties
storage temp. :-20°
solubility :Soluble in DMSO (up to at least 25 mg/ml).
form :solid
color :Off-white
Stability :Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
solubility :Soluble in DMSO (up to at least 25 mg/ml).
form :solid
color :Off-white
Stability :Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Safety Information
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Description
SNS-314 is a pan-Aurora kinase inhibitor (IC50s = 9, 31, and 3.4 nM for Aurora A, B, and C, respectively). In a panel of 219 kinases, SNS-314 also inhibits TRKB, TRKA, FLT4, FMS, DDR2, AXL, and C-RAF (IC50s = 5-100 nM). SNS-314 inhibits Aurora B phosphorylation of histone H3 in HCT116 human colorectal carcinoma cells in vitro (EC50 = <16 nM) and in a mouse xenograft model at a dose of 50 mg/kg. It also inhibits tumor growth in A2780 ovarian, A375 melanoma, H1299 lung, MDA-MB-231 breast, and PC3 prostate cancer mouse xenograft models when administered biweekly for six weeks at a dose of 170 mg/kg.Related product price
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₹3702.15-4546.5 - Aurora A Inhibitor I
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Suppliers and manufacturers
Dideu Industries Group Limited
![N-(3-Chlorophenyl)-N'-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-2-thiazolyl]urea methanesulfonate (1:1)](/ProductImageEN/2022-08/small/0d3fd41a-d276-4272-ae62-e5420bbbff32.jpg)
CLEARSYNTH LABS LTD.
ATK CHEMICAL COMPANY LIMITED
CONIER CHEM AND PHARMA LIMITED
TargetMol Chemicals Inc.
Career Henan Chemica Co
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
Aladdin Scientific
Amadis Chemical Company Limited
₹1.10 /1g
N-(3-Chlorophenyl)-N'-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-2-thiazolyl]urea methanesulfonate (1:1) CAS:1146618-41-8
N-(3-Chlorophenyl)-N'-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-2-thiazolyl]urea methanesulfonate (1:1) CAS:1146618-41-8