Bortezomib
- ₹12940
- Product name: Bortezomib
- CAS: 179324-69-7
- MF: C19H25BN4O4
- MW: 384.24
- EINECS:605-854-3
- MDL Number:MFCD09056737
- Synonyms:Boronic acid, B-[(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]bu;MG-341 PS-341;BortezoMib Base;bortezoMib(other);MLM341;BortezoMib R;VELCADE(BORTEZOMIB);Boronic acid, B-[(1R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]-
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Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- ManufacturerSigma-Aldrich(India)
- Product number5.04314
- Product descriptionBortezomib - CAS 179324-69-7 - Calbiochem Bortezomib, CAS 179324-69-7, is a cell-permeable, selective, slowly reversible inhibitor of 20S proteasome β5 ChTL/chymotrypsin- over β1 CL/caspase- a
- Packaging5MG
- Price₹12940
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 5.04314 | Bortezomib - CAS 179324-69-7 - Calbiochem Bortezomib, CAS 179324-69-7, is a cell-permeable, selective, slowly reversible inhibitor of 20S proteasome β5 ChTL/chymotrypsin- over β1 CL/caspase- a | 5MG | ₹12940 | 2022-06-14 | Buy |
Properties
Melting point :122-124°C
Density :1.214
RTECS :ED7771666
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :Soluble in chloroform, dimethyl sulfoxide, ethanol and methanol.
form :solid
pka :9.66±0.43(Predicted)
color :White
Stability :Hygroscopic and Moisture Sensitive
CAS DataBase Reference :179324-69-7(CAS DataBase Reference)
Density :1.214
RTECS :ED7771666
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :Soluble in chloroform, dimethyl sulfoxide, ethanol and methanol.
form :solid
pka :9.66±0.43(Predicted)
color :White
Stability :Hygroscopic and Moisture Sensitive
CAS DataBase Reference :179324-69-7(CAS DataBase Reference)
Safety Information
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Description
Bortezomib, a modified dipeptidyl boronic acid, is a therapeutic proteasome inhibitors used for the treatment of cancers. It is indicated for the treatment of relapsed multiple myeloma and mantle cell lymphoma. It is capable of inhibiting the mammalian 26S proteasome, which is important in regulating the intracellular concentration of specific proteins to maintain homeostasis within cells. The disruption of 26S proteasome function disrupts normal cellular homeostasis, leading to cytotoxic effect on various kinds of cancer cells.Related product price
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