Dasatinib
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- ₹3702.15 - ₹4546.5
- Product name: Dasatinib
- CAS: 302962-49-8
- MF: C22H26ClN7O2S
- MW: 488.01
- EINECS:801-607-0
- MDL Number:MFCD11046566
- Synonyms:N-(2-chloro-6-Methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-Methyl-4-pyriMidinyl]aMino]-1,3-thiazole-5-carboxaMide;sprycel Dasatinib;BMS-354825; SPRYCEL;25MG/100MG/1G;NCGC00181129;Dasatinib (Dasatinib Monohydrate) Tablet;Dasatinib (anhydrous);Dasatinib, 95+%
2 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 25MG
- 50MG
- ManufacturerSigma-Aldrich(India)
- Product numberCDS023389
- Product descriptionDasatinib
- Packaging25MG
- Price₹3702.15
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML2589
- Product descriptionDasatinib ≥98% (HPLC)
- Packaging50MG
- Price₹4546.5
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | CDS023389 | Dasatinib | 25MG | ₹3702.15 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | SML2589 | Dasatinib ≥98% (HPLC) | 50MG | ₹4546.5 | 2022-06-14 | Buy |
Properties
Melting point :275-286°C
Density :1.408±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 200 mg/ml).
pka :10.94±0.70(Predicted)
form :White powder.
color :White or off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
InChIKey :ZBNZXTGUTAYRHI-UHFFFAOYSA-N
SMILES :S1C(C(NC2=C(C)C=CC=C2Cl)=O)=CN=C1NC1C=C(N2CCN(CCO)CC2)N=C(C)N=1
CAS DataBase Reference :302962-49-8(CAS DataBase Reference)
Density :1.408±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 200 mg/ml).
pka :10.94±0.70(Predicted)
form :White powder.
color :White or off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
InChIKey :ZBNZXTGUTAYRHI-UHFFFAOYSA-N
SMILES :S1C(C(NC2=C(C)C=CC=C2Cl)=O)=CN=C1NC1C=C(N2CCN(CCO)CC2)N=C(C)N=1
CAS DataBase Reference :302962-49-8(CAS DataBase Reference)
Safety Information
Symbol(GHS): |
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Description
Dasatinib is a potent inhibitor of the non-receptor tyrosine kinases Abl and Src as well as other members of the Src family. It is effective at sub-nanomolar concentrations, inhibiting Src, Abl, and Lck with IC50 values of 0.05, 0.5, and 0.4 nM, respectively. At nanomolar concentrations, dasatinib also blocks the activity of several other receptor and non-receptor tyrosine kinases, plus drug resistant mutants. Because of these activities, dasatinib has potential therapeutic value in diseases that are characterized by elevated levels of these kinases, including some forms of cancer and fibrotic disease.Related product price
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