tridihexethyl iodide

tridihexethyl iodide  Structure
CAS No.
125-99-5
Chemical Name:
tridihexethyl iodide
Synonyms
Tridihexethl;Tridihexethyl;tridihexethyl iodide
CBNumber:
CB9883161
Molecular Formula:
C21H36NO.I
Molecular Weight:
445.421
MOL File:
125-99-5.mol
Modify Date:
2023/5/4 17:34:32

tridihexethyl iodide Properties

Melting point 179-184°

SAFETY

Risk and Safety Statements

Toxicity LD50 oral in rat: 1100mg/kg

tridihexethyl iodide Chemical Properties,Uses,Production

Originator

Pathilon,Burroughs-Wellcome,US,1955

Manufacturing Process

Acetophenone, paraformaldehyde and diethylamine are first reacted to give ω- diethylaminopropiophenone. That is reacted with cyclohexylmagnesium bromide to give 3-diethylamino-1-cyclohexyl-1-phenylpropanol-1. To 1,320 parts of methyl isobutyl ketone is added 570 parts of 3- diethylamino-1-cyclohexyl-1-phenylpropanol-1 (2 mols) and the mixture is stirred until solution is complete. Then 500 parts (3.2 molsor 60% excess) of ethyl iodide are added. After filtration, the filtrate is diluted with an additional 300 parts of methyl isobutyl ketone and the solution is then heated at the reflux temperature (108°C to 110°C) for 9 hours. After cooling to 0°C, the precipitated solid material is removed by filtration, washed with isopropyl acetate and dried. Approximately 777 parts of product is obtained or a yield of 88.6% based on as-is starting material or 92.5% based on real starting material.

Therapeutic Function

Anticholinergic

tridihexethyl iodide Preparation Products And Raw materials

Raw materials

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Preparation Products

tridihexethyl iodide Suppliers

Global( 2)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Lanospharma Laboratories Co.,Ltd 13440048448 China 6343 56 Inquiry
Shaanxi Dideu Medichem Co. Ltd 029-81124267 15229202216 China 10011 58 Inquiry
tridihexethyl iodide Tridihexethl Tridihexethyl 125-99-5 C21H36INO C21H36NOI