2-アセチルチアゾール 化学特性,用途語,生産方法
外観
無色～うすい黄色、液体
用途
有機合成原料。
化学的特性
2-Acetylthiazole is a colorless to pale yellow liquid with green onion, herbal, grassy, hazelnuts, roasted meat, caramel, corn, and butter odor. Natural products are found in beef broth. Slightly soluble with water, soluble in most organic solvents. It is used in foods as antioxidant, as appearance control agent, and as flavoring ingredient.
天然物の起源
2-Acetylthiazole is naturally found in raw asparagus, cooked asparagus, kohlrabi, cooked or boiled potatoes, turkey (roasted), raw chicken, boiled and cooked beef, grilled and roasted beef, pork liver, beer, Finnish whiskey, heated beans, other varieties of mushroom, rice bran, maize, and other natural sources.
使用
2-Acetylthiazole can be used as a flavoring agent in food industries. It may be used as a food additive in the preparation of ′fragrant′ rice. It also was used in the preparation of triazolothiazoles, chiral alcohols and in aldol condensation reactions.
製造方法
2-Acetylthiazole is formed by oxidation of the corresponding carbinol using dichromate.
一般的な説明
2-Acetylthiazole is a volatile flavoring substance generally formed by the Maillard reaction between an amino acid and carbonyl compounds. It is reported to occur in canned sweet corn products, cooked pine mushroom, cooked asparagus and roasted beef.
純化方法
Check NMR spectrum; if it is not too bad, distil it through an efficient column in a vacuum. The oxime sublimes at 140-145o, m 159o, and when crystallised from H2O has m 163-165.5o. [Erlenmeyer et al. Helv Chim Acta 31 1142 1948, Waisvisz et al. J Am Chem Soc 79 4524 1957, Menasseé et al. Helv Chim Acta 40 554 1957, Beilstein 27 IV 2617.]
2-アセチルチアゾール 上流と下流の製品情報
原材料
準備製品
1,2,5,6-Tetrathiocane
2,5-ジヒドロチオフェン
5-クロロチアゾール-2-エタノン
4,4,4-トリフルオロ-1-(1,3-チアゾール-2-イル)ブタン-1,3-ジオン
2-Thiazolemethanol, alpha-methyl-, (alphaS)- (9CI)
3-(ジメチルアミノ)-1-(1,3-チアゾール-2-イル)-2-プロペン-1-オン