Phenazine methosulfate
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Phenazine methosulfate 속성
- 녹는점
- 158-160 °C (dec.)(lit.)
- 밀도
- 1.3395 (rough estimate)
- 굴절률
- 1.6930 (estimate)
- 저장 조건
- -20°C
- 용해도
- H2O: 20 °C에서 0.2 g/mL, 투명, 진한 주황색
- 물리적 상태
- 결정성 분말
- 색상
- 진한 노란색에서 갈색 또는 카키색
- 수용성
- soluble in water (approximately 200 mg/ml).
- 감도
- Light Sensitive
- Merck
- 14,6109
- BRN
- 3898869
- 안정성
- 안정적인. 강한 산화제와 호환되지 않습니다.
- CAS 데이터베이스
- 299-11-6(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi,Xn,T | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38-68-46 | ||
| 안전지침서 | 26-36/37/39-53-45 | ||
| 유엔번호(UN No.) | 2811 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | SG1645000 | ||
| F 고인화성물질 | 8 | ||
| TSCA | Yes | ||
| HS 번호 | 29339900 |
Phenazine methosulfate C화학적 특성, 용도, 생산
개요
Phenazine is a free radical generator. It has been used as an electron transfer reactant in cell viability assays. Phenazine (10 μM) induces ssDNA break formation in the presence of the reducing agent NADPH in a cell-free plasmid cleavage assay when used at a concentration of 10 μM. It induces oxidative DNA damage in an alkaline comet assay and apoptosis in A375 melanoma cells when used at a concentration of 10 μM. Phenazine (20 nM) oxidizes cysteine-containing proteins in HepG2 cells.화학적 성질
orange to light brown crystals or powder용도
Phenazine Methosulfate is used in tyrosine transaminase test and for enzymic determination of ethanol in blood by the colorimetric micromethod. Used with ascorbic acid to determine nitric oxide reductase activity. Since the reduced PMS is easily oxidized by oxygen, it is used in assays as an electron carrier between enzymes and oxygen, cytochrome c, indophenols, or tetrazolium salts. The reduced PMS is used as an electron donor to reduce cytochrome c or in photosynthetic experiments. Usage of PMS for detection of specific dehydrogenases has been reported.정의
ChEBI: 5-methylphenazinium methyl sulfate is an azaheterocycle sulfate salt and a member of phenazines. It is used as an electron carrier in place of the flavine enzyme of Warburg in the hexosemonophosphate system and also in the preparation of succinic dehydrogenase. Green et al., J. Biol. Chem. 217, 551 (1955).주요 응용
Phenazine methosulfate is a compound used to determine nitric oxide reductase activity. Phenazine methosulfate has been used:as a component of succinate dehydrogenase enzyme substrate solution.
to induce superoxide radical generation in red blood cell suspensions and to study its influence on RBC deformability.
as a component of complex II histochemistry media.
Used in the discovery of potent bromophenazine antibacterial agents against Staphylococcus.
일반 설명
Phenazines are heterocyclic compounds produced as secondary metabolites by bacteria.Purification Methods
It forms yellow-brown prisms from EtOH (charcoal), or EtOH/Et2O. Its solubility in H2O at 20o is 10%. In the presence of aqueous KI it forms a semiquinone which crystallises as blue leaflets from EtOH. [Wieland & Roseen Chem Ber 48 1117 1913, Voriskova Collect Czech Chem Commun 12 607 1947, Bülow Chem Ber 57 1431 1924, Campbell et al. J Chem Soc 404 1938, Morley J Chem Soc 4008 1952, Beilstein 23 I 59, 23 II 234, 23 III/IV 1658, 23/8 V 395.]Phenazine methosulfate 준비 용품 및 원자재
원자재
니트로톨루엔
페나진
톨루엔
디에틸에테르
디메틸설페이트
Phenazine, 5,10-dihydro-5,10-bis(phenylmethyl)-
Phenazine, 5,10-dihydro-5-methyl-10-(phenylmethyl)-
5,10-디히드로-5-메틸페나진
2-니트로디페닐아민
5,10-디하이드로페나진
5,10-디메틸디히드로페나진
아닐린
O-클로로니트로벤젠
카테콜
O-페닐렌다이아민
O-플루오로니트로벤젠
준비 용품
Phenazine methosulfate 공급 업체
글로벌( 344)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Guanlang Biotechnology Co,.LTD | +8619930503252 |
daisy@crovellbio.com | China | 5828 | 58 |
| Anhui Zhongda Biotechnology Co., Ltd | +8615689548120 |
linda@zhongda-biotech.com | China | 204 | 58 |
| Shaanxi Franta Biotechnology Co., Ltd | +86-13082019107 +86-13082019107 |
admin@flanderff.com | China | 225 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29798 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 16914 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21668 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32760 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29894 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |