네파조돈

네파조돈
네파조돈 구조식 이미지
카스 번호:
83366-66-9
한글명:
네파조돈
동의어(한글):
네파조돈
상품명:
Nefazodone
동의어(영문):
SERZONE;Dutonin;Nefadar;BMY-13754;NEFAZODONE;MJ-13754-1;MJ-13754-I;Nefazodone base;l)-5-ethyl-4-(2-phenoxyethyl)-;Nefazodone (base and/or unspecified salts)
CBNumber:
CB5144862
분자식:
C25H32ClN5O2
포뮬러 무게:
470.01
MOL 파일:
83366-66-9.mol

네파조돈 속성

녹는점
180-182°C
끓는 점
599.6±60.0 °C(Predicted)
밀도
1.23±0.1 g/cm3(Predicted)
저장 조건
2-8°C
용해도
DMSO: ~11mg/mL( 60 °C)
물리적 상태
고체
물리적 상태
단단한 모양
산도 계수 (pKa)
pKa 6.5 (Uncertain)
색상
하얀색
CAS 데이터베이스
83366-66-9(CAS DataBase Reference)
NIST
Nefazodone(83366-66-9)

안전

안전지침서 22-24/25
WGK 독일 3
유해 물질 데이터 83366-66-9(Hazardous Substances Data)

네파조돈 C화학적 특성, 용도, 생산

화학적 성질

Crystalline Solid

용도

A selective serotonin 5-HT2 receptor antagonist. An antidepressant

Biological Functions

Although nefazodone (Serzone) is structurally related to trazodone, it is less sedating. It does not block α1- adrenoreceptors, and its use is not associated with priapism. Nefazodone inhibits the neuronal reuptake of serotonin and blocks 5HT2A receptors. Its short half-life requires dosing twice a day. Nefazodone is not associated with weight gain or sexual dysfunction. It inhibits the cytochrome P450 3A4 isoenzyme that is responsible for 50% of known oxidative metabolism, and therefore, nefazodone can elevate levels of drugs dependent on this pathway for metabolism.

네파조돈 준비 용품 및 원자재

원자재

준비 용품


네파조돈 공급 업체

글로벌( 64)공급 업체
공급자 전화 이메일 국가 제품 수 이점
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32820 60
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29886 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873
sales@chemdad.com China 39894 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49374 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32038 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418684 +8618949823763
sales@tnjchem.com China 25356 58
Shaanxi Didu New Materials Co. Ltd
+86-89586680 +86-13289823923
1026@dideu.com China 8670 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207
sales@molcore.com China 49734 58
TargetMol Chemicals Inc.

support@targetmol.com United States 38463 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652
info@fdachem.com China 20288 58

Copyright 2019 © ChemicalBook. All rights reserved