SCRIPTAID

SCRIPTAID 구조식 이미지
카스 번호:
287383-59-9
상품명:
SCRIPTAID
동의어(영문):
CS-1136;GCK 1026;Scriptide;Scriptaid (GCK1026);Scriptaid, Scriptide;GCK 1026; SCRIPTIDE; GCK1026; GCK-1026;6-(1,3-dioxobenzo[de]isoquinolin-2-yl)-N-hydroxyhexanamide;1H-Benz[de]isoquinoline-2(3H)-hexanamide, N-hydroxy-1,3-dioxo-;6-(1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)-N-hydroxyhexanaMide;Scriptide N-Hydroxy-1,3-dioxo-1H-benz[de]isoquinoline-2(3H)-hexanamide
CBNumber:
CB5504770
분자식:
C18H18N2O4
포뮬러 무게:
326.35
MOL 파일:
287383-59-9.mol
MSDS 파일:
SDS

SCRIPTAID 속성

녹는점
160-161 °C
밀도
1.338±0.06 g/cm3(Predicted)
저장 조건
-20°C
용해도
DMSO에 용해됩니다(최대 4mg/ml).
산도 계수 (pKa)
9.46±0.20(Predicted)
물리적 상태
노란색 고체.
색상
하얀색
감도
Light Sensitive
안정성
제공된 대로 구매일로부터 2년 동안 안정적입니다. DMSO의 솔루션은 -20°에서 최대 2개월 동안 보관할 수 있습니다.

안전

WGK 독일 3

SCRIPTAID C화학적 특성, 용도, 생산

개요

Scriptaid is a histone deacetylase inhibitor that has an optimal concentration of 6-8 μM in a cell-based assay, is less toxic than trichostatin A, and works in a wide variety of biological systems. It induces cell cycle arrest in colon cancer cells in culture and inhibits tumor growth in vitro and in vivo. Scriptaid also facilitates the cloning of inbred mouse strains produced by somatic cell nuclear transfer.

용도

Scriptaid has been used in post activation of oocytes and embryo culture.

일반 설명

Scriptaid is a histone deacetylase (HDAC) inhibitor, which enhances global acetylation of histones. It improves transcriptional activity and protein expression. Scriptaid inhibits tumor growth. It decreases telomerase activity and stimulates glioma cell apoptosis.

생물학적 활성

Novel histone deacetylase inhibitor. Produces > 100-fold increase in histone acetylation and displays relatively low toxicity.

SCRIPTAID 준비 용품 및 원자재

원자재

준비 용품


SCRIPTAID 공급 업체

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Hebei Mojin Biotechnology Co., Ltd
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ATK CHEMICAL COMPANY LIMITED
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career henan chemical co
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Zhejiang J&C Biological Technology Co.,Limited
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sales@sarms4muscle.com China 10522 58
InvivoChem
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Nantong HI-FUTURE Biology Co., Ltd.
+undefined18051384581
sales@chemhifuture.com China 3136 58
TargetMol Chemicals Inc.
+1-781-999-5354
support@targetmol.com United States 19973 58
ShenZhen Trendseen Biological Technology Co.,Ltd.
13417589054
trendseenbio@gmail.com China 11681 58
LEAPCHEM CO., LTD.
+86-852-30606658
market18@leapchem.com China 43348 58

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