5-Fluorouracil
5-Fluorouracil
- CAS:
- 51-21-8
- MF:
- C4H3FN2O2
- MW:
- 130.08
Suppliers by country/region
- India(38)
- CHINA(410)
- United States(93)
- Germany(16)
- United Kingdom(34)
- Canada(6)
- Europe(5)
- France(4)
- Switzerland(5)
- Russia(1)
- Italy(1)
- Japan(7)
- Ukraine(1)
- Slovakia(1)
- Belgium(3)
- Israel(2)
- Slovenia(1)
- The Netherlands(1)
- Egypt(1)
- Brazil(4)
- Poland(1)
- Hungary(1)
- Australia(1)
- Czech Republic(1)
- Spain(1)
- Nepal(1)
Company Type
Properties
- Melting point:
- 282-286 °C (dec.) (lit.)
- Boiling point:
- 190-200°C/0.1mmHg
- Density
- 1.4593 (estimate)
- storage temp.
- 2-8°C
- solubility
- H2O: 10 mg/mL, clear
- form
- powder
- pka
- pKa 8.0±0.1 (H2O) (Uncertain);3.0±0.1(H2O) (Uncertain)
- color
- white
- PH
- 4.3-5.3 (10g/l, H2O, 20℃)
- Water Solubility
- 12.2 g/L 20 ºC
- Sensitive
- Air Sensitive
- Merck
- 14,4181
- BRN
- 127172
- Stability:
- Stable. Light sensitive. Combustible. Incompatible with strong oxidizing agents, strong bases.
- InChIKey
- GHASVSINZRGABV-UHFFFAOYSA-N
Safety Information
- Symbol(GHS)
GHS06,GHS08
- Signal word
- Danger
- Hazard statements
- H301-H351
- Precautionary statements
- P201-P202-P264-P270-P280-P301+P310
- Hazard Codes
- Xn,T,C,Xi
- Risk Statements
- 22-20/21/22-52-25
- Safety Statements
- 36-36/37-36/37/39-22-45-26
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- RTECS
- YR0350000
- F
- 10-23
- Hazard Note
- Irritant/Highly Toxic
- TSCA
- T
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29335995
- Toxicity
- LD50 orally in Rabbit: 230 mg/kg
Use
5-Fluorouracil is used as an antitumor agent in the treatment of anal, breast, colorectal, oesophageal, stomach, pancreatic and skin cancers. It finds application as a suicide inhibitor due to its irreversible inhibition of thymidylate synthase. It is also used in the treatment of actinic keratoses and bowen's disease. Further, it serves as a potent antineoplastic agent in clinical use. In addition to this, it acts as a DNA synthesis inhibitor.
38 India supplier list of "5-Fluorouracil"
- Product Name:5-Fluorouracil, 98%
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Trader
- Country/Region: INDIA
- Product Name:5-Fluorouracil
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Flucytosine EP Impurity A
- Products Intro:Purity: 98% | Package: 50 MG; 100 MG; 250 MG ; 2 GM
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:5-Fluorouracil
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:5-Fluoro Uracil
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Trader
- Country/Region: INDIA
- Product Name:5-Fluorouracil
- Products Intro:Brand:sigma aldrich | Product Number:03738 | Purity:analyticalstandard
- Company Type: Trader
- Country/Region: INDIA
- Product Name:Fluorouracil 99% (HPLC), powder
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.073063
- Company Type: Trader
- Country/Region: INDIA
- Product Name:5-Fluorouracil
- Company Type: Trader
- Country/Region: INDIA
- Product Name:5-Fluorouracil
- Company Type: Trader
- Country/Region: INDIA
- Product Name:5-Fluorouracil
- Company Type: Trader
- Country/Region: INDIA