Agomelatine
AGOMELATINE
- CAS:
- 138112-76-2
- MF:
- C15H17NO2
- MW:
- 243.3
Suppliers by country/region
Company Type
Properties
- Melting point:
- 107-109°C
- Boiling point:
- 478.8±28.0 °C(Predicted)
- Density
- 1.109±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: >50mg/mL
- pka
- 16.17±0.46(Predicted)
- form
- powder
- color
- white to off-white
- Merck
- 14,190
- InChI
- InChI=1S/C15H17NO2/c1-11(17)16-9-8-13-5-3-4-12-6-7-14(18-2)10-15(12)13/h3-7,10H,8-9H2,1-2H3,(H,16,17)
- InChIKey
- YJYPHIXNFHFHND-UHFFFAOYSA-N
- SMILES
- C(NCCC1=C2C(C=CC(OC)=C2)=CC=C1)(=O)C
Safety Information
- Symbol(GHS)
GHS09
- Signal word
- Warning
- Hazard statements
- H400
- Precautionary statements
- P273
- Hazard Codes
- N
- Risk Statements
- 50
- Safety Statements
- 61
- RIDADR
- UN 3077 9 / PGIII
- WGK Germany
- 3
- RTECS
- AC5956323
- HS Code
- 29241990
- Toxicity
- mouse,LD50,oral,> 1gm/kg (1000mg/kg),United States Patent Document. Vol. #5318994,
Use
Agomelatine is a melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression. Agomelatine (S20098) displayed pKi values of 6.4 and 6.2 at native (porcine) and cloned, human (h)5-hydroxytryptamine (5-HT)2C receptors, respectively.
57 India supplier list of "AGOMELATINE"
- Product Name:Agomelatine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Agomelatine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Agomelatine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
- Product Name:Agomelatine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Agomelatine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Agomelatine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
- Product Name:Agomelatine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Reagent
- Country/Region: Hyderabad,INDIA
- Product Name:Agomelatine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Agomelatine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:Agomelatine
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA