Azasetron hydrochloride
Azasetron hydrochloride
- CAS:
- 123040-16-4
- MF:
- C17H21Cl2N3O3
- MW:
- 386.27
Suppliers by country/region
Company Type
Properties
- Melting point:
- 281° (dec); mp 305° (dec) (Kawakita)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Methanol (Slightly), Water (Slightly)
- form
- White solid.
- color
- White
Safety Information
- Symbol(GHS)
GHS08
- Signal word
- Warning
- Hazard statements
- H361
- Precautionary statements
- P201-P202-P281-P308+P313-P405-P501
- Toxicity
- LD50 in male, female rats (mg/kg): 135, 132 i.v. (Takagi)
Use
Nazasetron (azasetron) hydrochloride is the fourth in the class of highly potent 5- HT3 receptor antagonists to reach the market for prophylaxis of severe nausea and vomiting induced by cytotoxic chemotherapy and by total body X-radiation. In a study with 146 cancer patients suffering from emesis induced by cisplatin, nazasetron was reported to be markedly effective in 72% of subjects. Nazasetron is devoid of dopamine D2 receptor blocking activity and therefore is free of the extrapyrimidal side effects associated with other commonly used antiemetics such as metoclopramide and domperidone. Nazasetron has been reported to be potentially useful for the treatment of gastrointestinal motility dysfunction, such as gastric stasis, vomiting and irritable bowel syndrome.
3 India supplier list of "Azasetron hydrochloride"
- Product Name:Azasetron
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Tamil Nadu,INDIA
- Product Name:Azasetronhydrochloride
- Products Intro:Brand:sigma aldrich | Product Number:SML2491 | Purity:≥98%(HPLC)
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:Azasetron hydrochloride 98% (HPLC)
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.040772
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Azasetron hydrochloride
- Company Type: Reagent
- Country/Region: Mumbai,INDIA
- Product Name:Azasetronhydrochloride
- Products Intro:Brand:ajchemicals | Product Number:JDH-26434 | Purity:98+%
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:AzasetronHydrochloride
- Products Intro:Brand:clearsynth | Product Number:CS-T-48456
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:Semi-synthetic fatty acid glycerides
- Products Intro:Purity: 98% HPLC | Package: 5G;10G;25G;50G;100G;250G;1KG
- Company Type: Reagent
- Country/Region: CHINA
- Product Name:Azasetron hydrochloride
- Products Intro:Purity: 99% | Package: 1kg;7USD
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
$7.00/ 1kg
- Product Name:Azasetron HCl
- Company Type: Service provider
- Country/Region: CHINA
- Main Products: UDDA
- Product Name:Azasetron hydrochloride
- Products Intro:Purity: 0.98 | Package: 1kg，2kg，5kg，10kg，25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 2,7-ADA,2,4,6-Trichloroaniline,TRIMETHYLOXONIUM TETRAFLUOROBORATE,Zinc sulfide,5-HEXEN-1-OL