Cefprozil manufacturers and suppliers in india

Cefprozil

Properties

Melting point:: 215-217°C (dec.)

Boiling point:: 803℃

Density: 1.53±0.1 g/cm3(Predicted)

RTECS: XI0339000

Flash point:: >110°(230°F)

storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

solubility: DMF: 0.3 mg/ml; DMSO: 2.5 mg/ml; PBS (pH 7.2): 1.25 mg/ml

form: Powder

pka: 2.92±0.50(Predicted)

Water Solubility: Soluble in DMSO at 10mg/ml. Insoluble in water.

BCS Class: 3

InChIKey: WDLWHQDACQUCJR-PBFPGSCMSA-N

SMILES: N12[C@@]([H])([C@H](NC([C@H](N)C3=CC=C(O)C=C3)=O)C1=O)SCC(C=CC)=C2C(O)=O

Safety Information

Use

Cefprozil (Cefzil) is an orally active second-generationcephalosporin that is similar in structure and antibacterialspectrum to cefadroxil. Oral absorption is excellent (oralbioavailability is about 95%) and is not affected by antacidsor histamine H2-antagonists. Cefprozil exhibits greater invitro activity against streptococci, Neisseria spp., and S. aureusthan does cefadroxil. It is also more active than thefirst-generation cephalosporins against members of theEnterobacteriaceae family, such as E. coli, Klebsiella spp., P. mirabilis, and Citrobacter spp. The plasma half-life of1.2 to 1.4 hours permits twice-a-day dosing for the treatmentof most community-acquired respiratory and urinary tractinfections caused by susceptible organisms.