Closantel
Closantel
- CAS:
- 57808-65-8
- MF:
- C22H14Cl2I2N2O2
- MW:
- 663.07
Suppliers by country/region
Company Type
Properties
- Melting point:
- 217.8°
- Boiling point:
- 590.5±50.0 °C(Predicted)
- Density
- 1.8759 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,2-8°C
- solubility
- DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2)(1:5): 0.16 mg/ml
- form
- Solid
- pka
- 5.99±0.48(Predicted)
- color
- White to off-white
Safety Information
- Symbol(GHS)
GHS06
- Signal word
- Danger
- Hazard statements
- H301-H413
- Precautionary statements
- P273-P301+P310+P330
- Hazard Codes
- Xn
- Risk Statements
- 22
- RIDADR
- 2811
- WGK Germany
- 3
- RTECS
- CV2444250
- HazardClass
- 6.1(b)
- PackingGroup
- III
- Toxicity
- A veterinary drug for the treatment of fluke and nematode infestations. In 1993, some was included in a batch of donated drugs sent to Lithuania. Attempts to match the product with the names of other medicines on accompanying literature resulted in its misidentification as a treatment for endometriosis. Eleven women lost their eyesight; though this has since returned, they were left with eye pain and are unable to work.
Use
Closantel is a kind of synthetic anti parasitic agent which is actively against liver fluke, bloodsucking nematodes and larval stages of some arthropods in sheep and cattle. Its mechanism of action is through decoupling the mitochondrial oxidative phosphorylation, thus inhibiting the production of ATP. Therefore, it inhibit their energy generation of the parasite, causing their death. It is mainly used for the treatment and prevention of several infections caused by many kinds of parasites such as Fasciola hepatica, Fasciola gigantica, Haemonchus concortus, Haemonchus placei, Bunostomum phlebotomum, Oesophagostomum radiatum and Strongyloides papillosus in cattle and sheep.
22 India supplier list of "Closantel"
- Product Name:Closantel
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Closantel
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Reagent
- Country/Region: Hyderabad,INDIA
- Product Name:Closantel
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Closantel
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:Closantel
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Closantel
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Tamil Nadu,INDIA
- Product Name:Closantel
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:CLOSANTEL BASE
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Hyderabad,INDIA
- Product Name:Closantel
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:Closantel
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA