Isotretinoin
Isotretinoin
- CAS:
- 4759-48-2
- MF:
- C20H28O2
- MW:
- 300.44
Suppliers by country/region
Company Type
Properties
- Melting point:
- 172-175 °C (lit.)
- Boiling point:
- 381.66°C (rough estimate)
- Density
- 1.0597 (rough estimate)
- refractive index
- 1.4800 (estimate)
- storage temp.
- -20°C
- solubility
- Practically insoluble in water, soluble in methylene chloride, slightly soluble in ethanol (96 per cent). It is sensitive to air, heat and light, especially in solution. Carry out all operations as rapidly as possible and avoid exposure to actinic light; use freshly prepared solutions.
- pka
- 4.76±0.33(Predicted)
- form
- Fine Crystalline Powder
- color
- Yellow-orange to orange
- Water Solubility
- insoluble
- λmax
- 354nm(EtOH)(lit.)
- Merck
- 14,5228
- Stability:
- Stable, but probably air and light sensitive. Combustible. Incompatible with strong oxidizing agents.
- InChIKey
- SHGAZHPCJJPHSC-YCNIQYBTSA-N
Safety Information
- Symbol(GHS)
GHS07,GHS08
- Signal word
- Danger
- Hazard statements
- H315-H319-H335-H360
- Precautionary statements
- P201-P302+P352-P305+P351+P338-P308+P313
- Hazard Codes
- T
- Risk Statements
- 61-36/37/38-20/21/22
- Safety Statements
- 53-26-36/37/39-45-37/39
- WGK Germany
- 3
- RTECS
- VH6440000
- TSCA
- Yes
- HS Code
- 29362100
- Toxicity
- LD50 (20 day) in mice, rats (mg/kg): 904, 901 i.p.; 3389, >4000 orally (Kamm)
Use
Isotretinoin can rapidly and strongly inhibit the cell proliferation and differentiation process of skin glands cells. It has a high effect on severe nodular cystic acne. This product has a high gastrointestinal absorption, but invalid for topical administration. It is used for treating severe acnes which cannot be treated by other drugs. It also has some effects on treating cystic acne, the party of acne, rosacea, ichthyosis, follicular keratosis and pityriasis red hair and other skin diseases.
55 India supplier list of "Isotretinoin"
- Product Name:Isotretinoin EP IMP H
- Products Intro:Purity: 90 % Above | Package: 25 mg, 100 mg, 250 mg, 500 mg and 1.0 gm
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Isotretinoin
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Isotretinoin
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Isotretinoin
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Trader
- Country/Region: INDIA
- Product Name:Isotretinoin
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Isotretinoin
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Isotretinoin
- Products Intro:Purity: 99% | Package: 1kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Isotretinoin
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Isotretinoin
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Isotretinoin
- Products Intro:Brand:sigma aldrich | Product Number:PHR1188 | Purity:PharmaceuticalSecondaryStandard;CertifiedReferenceMaterial
- Company Type: Trader
- Country/Region: INDIA