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Lysergic acid diethylamide

Lysergic acid diethylamide

CAS:
50-37-3
MF:
C20H25N3O
MW:
323.44

Properties

Melting point:
91-93?C
alpha 
D20 +17° (c = 0.5 in pyridine)
Boiling point:
461.9°C (rough estimate)
Density 
1.1021 (rough estimate)
refractive index 
1.6200 (estimate)
Flash point:
2℃
storage temp. 
−20°C
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
form 
Solid
pka
pKa 7.5 (Uncertain)
color 
Pale Brown to Brown
Stability:
Stable. Incompatible with strong oxidizing agents.

Safety Information

Symbol(GHS) 

GHS02,GHS07,GHS06
Signal word 
Danger
Hazard statements 
H225-H302+H312+H332-H319-H302+H312-H331
Precautionary statements 
P210-P261-P302+P352+P312-P304+P340+P312-P337+P313-P403+P235-P403+P233
Hazard Codes 
T+,T,F,Xn
Risk Statements 
26/27/28-40-36/38-23/25-36-20/21/22-11
Safety Statements 
22-28-36-45-33-24-16-7-36/37-26
RIDADR 
UN 2811 6.1/PG 1
WGK Germany 
3
RTECS 
KE4100000
Toxicity
LD50 in mice, rats, rabbits (mg/kg): 46, 16.5, 0.3 i.v.
DEA Controlled Substances
CSCN: 7310
CAS SCH: III
NARC: N
DEA Controlled Substances
CSCN: 7310
CAS SCH: III
NARC: N

Use

Lysergic acid diethylamide(LSD) is obtained by partial synthesis fromD-lysergic acid. It is also produced bymicrobial reaction of Claviceps paspali overthe hydroxylethylamide. It is a well-knownhallucinogen and a drug of abuse, listed asa controlled substance in the U.S. Code ofFederal Regulations (Title 21, Part 1308.11,1987). It is used as an antagonist to serotoninand in the study and treatment of mentaldisorders.

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DiethylamineEthylenediamineLysergic acid diethylamideLSD-D3
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