Nifedipine
Nifedipine
- CAS:
- 21829-25-4
- MF:
- C17H18N2O6
- MW:
- 346.33
Suppliers by country/region
- India(99)
- CHINA(288)
- United States(71)
- Germany(14)
- United Kingdom(22)
- Russia(1)
- Canada(7)
- Europe(2)
- France(3)
- South Korea(3)
- Japan(8)
- Belgium(3)
- Switzerland(10)
- Italy(8)
- Philippines(1)
- Israel(3)
- Slovenia(1)
- Hungary(1)
- Czech Republic(2)
- Venezuela(1)
- Singapore(1)
- Poland(1)
- Austria(1)
- Spain(4)
- Nigeria(1)
- Brazil(2)
- Malaysia(1)
- Mexico(1)
- Ireland(1)
- United Arab Emirates(1)
- Jordan(1)
Company Type
Properties
- Melting point:
- 171-175 °C
- Boiling point:
- 481.08°C (rough estimate)
- Density
- 1.2109 (rough estimate)
- refractive index
- 1.5486 (estimate)
- storage temp.
- 2-8°C
- solubility
- DMSO: soluble
- form
- powder
- pka
- pKa -0.9/>13(DMF,t undefined) (Uncertain)
- color
- yellow
- Water Solubility
- <0.1 g/100 mL at 19.5 ºC
- Merck
- 14,6528
- BCS Class
- 2
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions are not stable and must be used within one working day.
- InChIKey
- CYCWGQFQPAYBHG-UHFFFAOYSA-N
- CAS DataBase Reference
- 21829-25-4(CAS DataBase Reference)
- NIST Chemistry Reference
- Nifedipine(21829-25-4)
- EPA Substance Registry System
- Dimethyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate (21829-25-4)
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P301+P312+P330
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26-36
- WGK Germany
- 1
- RTECS
- US7975000
- HazardClass
- IRRITANT
- HS Code
- 29333990
- Hazardous Substances Data
- 21829-25-4(Hazardous Substances Data)
- Toxicity
- LD50 in mice, rats (mg/kg): 494, 1022 orally; 4.2, 15.5 i.v. (Vater)
Use
The prototype of this class, nifedipine, has potent peripheralvasodilatory properties. It inhibits the voltage-dependentcalcium channel in the vascular smooth muscle but has littleor no direct depressant effect on the SA or AV nodes, eventhough it inhibits calcium current in normal and isolated cardiactissues. Nifedipine is more effective in patients whoseanginal episodes are caused by coronary vasospasm and isused in the treatment of vasospastic angina as well as classicangina pectoris. Because of its strong vasodilatory properties,it is used in selected patients to treat hypertension.
99 India supplier list of "Nifedipine"
- Product Name:Nifedipine
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Mumbai,INDIA
- Product Name:Nifedipine
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Karnataka,INDIA
- Product Name:Nifedipine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Nifedipine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Nifedipine
- Products Intro:Purity: 99% | Package: Kg to Mtons
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:Nifedipine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Nifedipine 3,5-dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4- dihydropyridine-3,5-dicarboxylate
- Products Intro:Purity: 96% | Package: 25 mg, 50 mg , 100mg or 500 mg
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:NIFEDIPINE 10% ER PELLETS
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Hyderabad,INDIA
- Product Name:Nifedipine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Mumbai,INDIA
- Product Name:Nifedipine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA