Piroxicam
Piroxicam
- CAS:
- 36322-90-4
- MF:
- C15H13N3O4S
- MW:
- 331.35
Suppliers by country/region
- India(122)
- China(257)
- Singapore(1)
- United States(67)
- United Kingdom(19)
- Russia(1)
- Canada(6)
- Germany(11)
- Europe(2)
- France(4)
- Austria(2)
- Japan(1)
- Switzerland(5)
- Italy(5)
- Slovenia(1)
- Philippines(1)
- Brazil(2)
- Poland(1)
- Spain(4)
- United Arab Emirates(1)
- Belgium(2)
- Uruguay(1)
- Jordan(1)
- Egypt(1)
- South Korea(1)
- Nigeria(1)
- Mexico(1)
- Malaysia(1)
- Iran(1)
Company Type
Properties
- Melting point:
- 198-200°C
- Density
- 1.3664 (rough estimate)
- refractive index
- 1.6320 (estimate)
- storage temp.
- 2-8°C
- solubility
- Practically insoluble in water, soluble in methylene chloride, slightly soluble in anhydrous ethanol. It shows polymorphism (5.9).
- pka
- 6.3 (2:1 dioxane-water)
- form
- Solid
- color
- White to Light yellow
- Water Solubility
- Soluble in water, ethanol, chloroform, ethyl acetate.
- λmax
- 358nm(H2O)(lit.)
- Merck
- 14,7506
- BCS Class
- 2
- InChIKey
- QYSPLQLAKJAUJT-UHFFFAOYSA-N
Safety Information
- Symbol(GHS)
GHS06,GHS08
- Signal word
- Danger
- Hazard statements
- H301-H373
- Precautionary statements
- P260-P264-P270-P301+P310-P314-P405
- Hazard Codes
- Xn,F,T
- Risk Statements
- 22-25
- Safety Statements
- 26-36
- RIDADR
- UN 2811
- WGK Germany
- 3
- RTECS
- DL0705000
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 29349990
- Toxicity
- LD50 orally in mice: 360 mg/kg (Wiseman)
Use
Piroxicam (Feldene) is the most widely used oxicam becauseof its once-daily dosing schedule. It is well absorbedafter oral administration and has a plasma half-life of 50hours, thus requiring a dose of only 20 to 30 mg oncedaily. It undergoes extensive hepatic metabolism, catalyzedby CYP2C9 to give 5-hydroxypiroxicam as its majormetabolite. Several piroxicam prodrugshave been synthesized via derivatization of the enol alcoholgroup (amipiroxicam, droxicam, and pivoxicam) to reducepiroxicam-induced GI irritation.
122 India supplier list of "Piroxicam"
- Product Name:Piroxicam
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Trader
- Country/Region: Maharashtra,INDIA
- Product Name:Piroxicam
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Piroxicam
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Piroxicam
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:Piroxicam
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Piroxicam
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Piroxicam
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Piroxicam
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Piroxicam 4-hydroxy-2-methyl-N-(pyridin-2-yl)-2H-benzo[e][1,2]thiazine-3- carboxamide 1,1-dioxide
- Products Intro:Purity: 96% | Package: 25 mg, 50 mg , 100mg or 500 mg
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Piroxicam
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA